Exhaustion of the CD8+ T Cell Compartment in Patients with Mutations in Phosphoinositide 3-Kinase Delta
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Exhaustion of the CD8+ T Cell Compartment in Patients with Mutations in Phosphoinositide 3-Kinase Delta
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-03-07
DOI
10.3389/fimmu.2018.00446
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mutations in the adaptor-binding domain and associated linker region of p110δ cause Activated PI3K-δ Syndrome 1 (APDS1)
- (2017) Lucie Heurtier et al. HAEMATOLOGICA
- Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
- (2017) Tanya I. Coulter et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Clinical Trial of the Anti-PD-L1 Antibody BMS-936559 in HIV-1 Infected Participants on Suppressive Antiretroviral Therapy
- (2017) Cynthia L. Gay et al. JOURNAL OF INFECTIOUS DISEASES
- Mutations in the adaptor-binding domain and associated linker region of p110δ cause Activated PI3K-δ Syndrome 1 (APDS1)
- (2017) Lucie Heurtier et al. HAEMATOLOGICA
- Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
- (2016) Brandon M. Hall et al. Aging-US
- Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study
- (2016) Elodie Elkaim et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Phosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8+T Cell Responses during Acute Viral and Intracellular Bacterial Infections
- (2016) Donald T. Gracias et al. JOURNAL OF IMMUNOLOGY
- Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial
- (2016) F Stephen Hodi et al. LANCET ONCOLOGY
- Ensembl 2017
- (2016) Bronwen L. Aken et al. NUCLEIC ACIDS RESEARCH
- Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
- (2016) K. E. Pauken et al. SCIENCE
- Convergence of Innate and Adaptive Immunity during Human Aging
- (2016) Branca I. Pereira et al. Frontiers in Immunology
- PI3Kδ Regulates the Magnitude of CD8+T Cell Responses after Challenge withListeria monocytogenes
- (2015) Verity Q. Pearce et al. JOURNAL OF IMMUNOLOGY
- Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
- (2015) James Larkin et al. NEW ENGLAND JOURNAL OF MEDICINE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Heterozygous splice mutation inPIK3R1causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K
- (2014) Carrie L. Lucas et al. JOURNAL OF EXPERIMENTAL MEDICINE
- T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion
- (2013) Daniel T Utzschneider et al. NATURE IMMUNOLOGY
- Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency
- (2013) Carrie L Lucas et al. NATURE IMMUNOLOGY
- A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection
- (2013) David Gardiner et al. PLoS One
- Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
- (2013) M. J. Fuller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphoinositide 3-Kinase Gene Mutation Predisposes to Respiratory Infection and Airway Damage
- (2013) I. Angulo et al. SCIENCE
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- Inhibitory Receptors on Lymphocytes: Insights from Infections
- (2012) P. M. Odorizzi et al. JOURNAL OF IMMUNOLOGY
- Progressive Loss of Memory T Cell Potential and Commitment to Exhaustion during Chronic Viral Infection
- (2012) J. M. Angelosanto et al. JOURNAL OF VIROLOGY
- CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction
- (2012) Yoav Peretz et al. PLoS Pathogens
- Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection
- (2011) T. Yamamoto et al. BLOOD
- Chronic Virus Infection Enforces Demethylation of the Locus that Encodes PD-1 in Antigen-Specific CD8+ T Cells
- (2011) Ben Youngblood et al. IMMUNITY
- Four faces of cellular senescence
- (2011) Francis Rodier et al. JOURNAL OF CELL BIOLOGY
- T cell exhaustion
- (2011) E John Wherry NATURE IMMUNOLOGY
- Apoptosis and aging: increased resistance to apoptosis enhances the aging process
- (2010) Antero Salminen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Features of responding T cells in cancer and chronic infection
- (2010) Peter S Kim et al. CURRENT OPINION IN IMMUNOLOGY
- The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function
- (2010) Bijan Raziorrouh et al. HEPATOLOGY
- The PD-1 pathway in tolerance and autoimmunity
- (2010) Loise M. Francisco et al. IMMUNOLOGICAL REVIEWS
- Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci
- (2010) Anthony P. Popkie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates
- (2010) Julie R. Brahmer et al. JOURNAL OF CLINICAL ONCOLOGY
- The emerging mechanisms of isoform-specific PI3K signalling
- (2010) Bart Vanhaesebroeck et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The PI3K Isoforms p110 and p110 Are Essential for Pre-B Cell Receptor Signaling and B Cell Development
- (2010) F. Ramadani et al. Science Signaling
- PI3 Kinase Signals BCR-Dependent Mature B Cell Survival
- (2009) Lakshmi Srinivasan et al. CELL
- Differential Association of Programmed Death-1 and CD57 with Ex Vivo Survival of CD8+ T Cells in HIV Infection
- (2009) C. Petrovas et al. JOURNAL OF IMMUNOLOGY
- Chronic Antigen Stimulation Alone Is Sufficient to Drive CD8+ T Cell Exhaustion
- (2009) C. M. Bucks et al. JOURNAL OF IMMUNOLOGY
- Enhancing SIV-specific immunity in vivo by PD-1 blockade
- (2008) Vijayakumar Velu et al. NATURE
- Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
- (2008) Shawn D Blackburn et al. NATURE IMMUNOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started