Clinical Trial of the Anti-PD-L1 Antibody BMS-936559 in HIV-1 Infected Participants on Suppressive Antiretroviral Therapy

Programed death-1/programed death-ligand 1 expression in lymph nodes of HIV infected patients

(2016) Amanda L. Gill et al.   AIDS

Prevalence of testosterone deficiency in HIV-infected men under antiretroviral therapy

(2016) Ana Rita Gomes et al.   BMC INFECTIOUS DISEASES

Immune-related adverse events with immune checkpoint blockade: a comprehensive review

(2016) J.M. Michot et al.   EUROPEAN JOURNAL OF CANCER

Novel Assays for Measurement of Total Cell-Associated HIV-1 DNA and RNA

(2016) Feiyu Hong et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Immune Checkpoint Inhibitors: Review and Management of Endocrine Adverse Events

(2016) Elisa González-Rodríguez et al.   ONCOLOGIST

Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection

(2016) Matthias Hoffmann et al.   PLoS Pathogens

Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports

(2016) Noha Abdel-Wahab et al.   PLoS One

Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development

(2015) Meina Liang et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Immune Checkpoint Inhibitors: New Insights and Current Place in Cancer Therapy

(2015) Ninh M. La-Beck et al.   PHARMACOTHERAPY

Improved Single-Copy Assays for Quantification of Persistent HIV-1 Viremia in Patients on Suppressive Antiretroviral Therapy

(2014) A. R. Cillo et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Enhancing Virus-Specific Immunity In Vivo by Combining Therapeutic Vaccination and PD-L1 Blockade in Chronic Hepadnaviral Infection

(2014) Jia Liu et al.   PLoS Pathogens

A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection

(2013) David Gardiner et al.   PLoS One

Human immune deficiency virus (HIV) infection and the hypothalamic pituitary adrenal axis

(2013) Minu M. George et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques

(2012) Ravi Dyavar Shetty et al.   JOURNAL OF CLINICAL INVESTIGATION

In Vivo Blockade of the PD-1 Receptor Suppresses HIV-1 Viral Loads and Improves CD4+ T Cell Levels in Humanized Mice

(2012) B. E. Palmer et al.   JOURNAL OF IMMUNOLOGY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

(2011) Damalie Nakanjako et al.   BMC INFECTIOUS DISEASES

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Immune Exhaustion Occurs Concomitantly With Immune Activation and Decrease in Regulatory T Cells in Viremic Chronically HIV-1–Infected Patients

(2010) Meenakshi Sachdeva et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands

(2009) Angela Meier et al.   AIDS

PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: Restricted expression of type I interferon receptor by CCR5-expressing leukocytes

(2008) Adriano Boasso et al.   CLINICAL IMMUNOLOGY

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

(2008) S. Palmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA