5′ Rapid Amplification of cDNA Ends and Illumina MiSeq Reveals B Cell Receptor Features in Healthy Adults, Adults With Chronic HIV-1 Infection, Cord Blood, and Humanized Mice

A Neutralizing Antibody Recognizing Primarily N -Linked Glycan Targets the Silent Face of the HIV Envelope

(2018) Tongqing Zhou et al.   IMMUNITY

The Individual and Population Genetics of Antibody Immunity

(2017) Corey T. Watson et al.   TRENDS IN IMMUNOLOGY

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

(2016) Mattia Bonsignori et al.   CELL

Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals

(2016) Amy E. Baxter et al.   Cell Host & Microbe

Antigenic landscape of the HIV-1 envelope and new immunological concepts defined by HIV-1 broadly neutralizing antibodies

(2016) Xueling Wu et al.   CURRENT OPINION IN IMMUNOLOGY

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

(2016) Daniel T. MacLeod et al.   IMMUNITY

Development of Broadly Neutralizing Antibodies and Their Mapping by Monomeric gp120 in Human Immunodeficiency Virus Type 1-Infected Humans and Simian-Human Immunodeficiency Virus SHIVSF162P3N-Infected Macaques

(2016) Manxue Jia et al.   JOURNAL OF VIROLOGY

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

(2016) J. G. Jardine et al.   SCIENCE

Clonify: unseeded antibody lineage assignment from next-generation sequencing data

(2016) Bryan Briney et al.   Scientific Reports

B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation

(2016) Jacob D. Galson et al.   Genome Medicine

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

(2015) Tongqing Zhou et al.   CELL

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

(2015) Xueling Wu et al.   CELL

BCR repertoire sequencing: different patterns of B-cell activation after two Meningococcal vaccines

(2015) Jacob D Galson et al.   IMMUNOLOGY AND CELL BIOLOGY

Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria

(2015) Jing Huang et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Reconstructing and mining the B cell repertoire with ImmunediveRsity

(2015) Bernardo Cortina-Ceballos et al.   mAbs

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

(2015) Jason Gorman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Timely and spatially regulated maturation of B and T cell repertoire during human fetal development

(2015) Erez Rechavi et al.   Science Translational Medicine

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

(2015) Jason Gorman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Practical guidelines for B-cell receptor repertoire sequencing analysis

(2015) Gur Yaari et al.   Genome Medicine

In-Depth Assessment of Within-Individual and Inter-Individual Variation in the B Cell Receptor Repertoire

(2015) Jacob D. Galson et al.   Frontiers in Immunology

Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies

(2014) Thomas B. Kepler et al.   Cell Host & Microbe

Levels of somatic hypermutations in B cell receptors increase during childhood

(2014) E. J. H. Schatorjé et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals

(2014) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

The HIV-1 gp120 CD4-Bound Conformation Is Preferentially Targeted by Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Sera from HIV-1-Infected Individuals

(2014) Maxime Veillette et al.   JOURNAL OF VIROLOGY

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

(2014) Nicole A. Doria-Rose et al.   NATURE

The promise and challenge of high-throughput sequencing of the antibody repertoire

(2014) George Georgiou et al.   NATURE BIOTECHNOLOGY

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

(2014) Brandon J DeKosky et al.   NATURE MEDICINE

An AAV Vector-Mediated Gene Delivery Approach Facilitates Reconstitution of Functional Human CD8+ T Cells in Mice

(2014) Jing Huang et al.   PLoS One

Characterizing immune repertoires by high throughput sequencing: strategies and applications

(2014) Jorg J.A. Calis et al.   TRENDS IN IMMUNOLOGY

Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding

(2014) Linling He et al.   Scientific Reports

The potential of the human immune system to develop broadly neutralizing HIV-1 antibodies

(2013) Yu Zhang et al.   AIDS

Complete Haplotype Sequence of the Human Immunoglobulin Heavy-Chain Variable, Diversity, and Joining Genes and Characterization of Allelic and Copy-Number Variation

(2013) Corey T. Watson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

(2013) Florian Klein et al.   CELL

Deep sequencing and Circos analyses of antibody libraries reveal antigen-driven selection of Ig VH genes during HIV-1 infection

(2013) Madelyne Xiao et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Characterization of Plasmablasts in the Blood of HIV-Infected Viremic Individuals: Evidence for Nonspecific Immune Activation

(2013) C. M. Buckner et al.   JOURNAL OF VIROLOGY

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts

(2013) J. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatic populations of PGT135–137 HIV-1-neutralizing antibodies identified by 454 pyrosequencing and bioinformatic

(2013) Jiang Zhu   Frontiers in Microbiology

IgM Repertoire Biodiversity is Reduced in HIV-1 Infection and Systemic Lupus Erythematosus

(2013) Li Yin et al.   Frontiers in Immunology

Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data

(2013) Gur Yaari et al.   Frontiers in Immunology

Characterization of human IgG repertoires in an acute HIV-1 infection

(2012) Weizao Chen et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies

(2012) Peter D. Kwong et al.   IMMUNITY

Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire

(2012) Bryan S. Briney et al.   IMMUNOLOGY

IgA Response in Preterm Neonates Shows Little Evidence of Antigen-Driven Selection

(2012) T. Rogosch et al.   JOURNAL OF IMMUNOLOGY

Origin, diversity, and maturation of human antiviral antibodies analyzed by high-throughput sequencing

(2012) Ponraj Prabakaran et al.   Frontiers in Microbiology

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

(2011) M. A. Berkowska et al.   BLOOD

Expressed antibody repertoires in human cord blood cells: 454 sequencing and IMGT/HighV-QUEST analysis of germline gene usage, junctional diversity, and somatic mutations

(2011) Ponraj Prabakaran et al.   IMMUNOGENETICS

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

Counting absolute numbers of molecules using unique molecular identifiers

(2011) Teemu Kivioja et al.   NATURE METHODS

Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease

(2011) Felix Breden et al.   PLoS One

High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans

(2011) Ramy Arnaout et al.   PLoS One

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation

(2011) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

(2011) X. Wu et al.   SCIENCE

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

(2011) R. Pejchal et al.   SCIENCE

Developmental Regulation of the Human Antibody Repertoirea

(2010) HARRY W. SCHROEDER et al.   Annals of the New York Academy of Sciences

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

(2010) Y.-C. Wu et al.   BLOOD

Reference values for B cell subpopulations from infancy to adulthood

(2010) H. Morbach et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

(2009) Johannes F. Scheid et al.   NATURE

HIV-1 and influenza antibodies: seeing antigens in new ways

(2009) Peter D Kwong et al.   NATURE IMMUNOLOGY

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

(2009) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic and functional heterogeneity of human memory B cells

(2008) Iñaki Sanz et al.   SEMINARS IN IMMUNOLOGY

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

(2007) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS