Adjuvant-Associated Peripheral Blood mRNA Profiles and Kinetics Induced by the Adjuvanted Recombinant Protein Candidate Tuberculosis Vaccine M72/AS01 in Bacillus Calmette–Guérin-Vaccinated Adults

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

(2017) Dmitri Kazmin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of T-cell immune responses in clinical trials of the candidate RTS,S malaria vaccine

(2017) Philippe Moris et al.   Human Vaccines & Immunotherapeutics

Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

(2017) Robert A. van den Berg et al.   Frontiers in Immunology

Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity

(2017) Margherita Coccia et al.   npj Vaccines

Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression

(2016) Belinda Phipson et al.   Annals of Applied Statistics

A blood RNA signature for tuberculosis disease risk: a prospective cohort study

(2016) Daniel E Zak et al.   LANCET

A Randomized, Controlled Safety, and Immunogenicity Trial of the M72/AS01 Candidate Tuberculosis Vaccine in HIV-Positive Indian Adults

(2016) Nagalingeswaran Kumarasamy et al.   MEDICINE

Safety and immunogenicity of the M72/AS01 E candidate tuberculosis vaccine in adults with tuberculosis: A phase II randomised study

(2016) Paul Gillard et al.   TUBERCULOSIS

T-cell activation is an immune correlate of risk in BCG vaccinated infants

(2016) Helen A. Fletcher et al.   Nature Communications

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Profiling the host immune response to tuberculosis vaccines

(2015) Helen A. Fletcher   VACCINE

Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting

(2015) Adam Penn-Nicholson et al.   VACCINE

Safety and immunogenicity of the M72/AS01 candidate tuberculosis vaccine in HIV-infected adults on combination antiretroviral therapy

(2014) Eleonora G. Thacher et al.   AIDS

Processing of blood samples influences PBMC viability and outcome of cell-mediated immune responses in antiretroviral therapy-naïve HIV-1-infected patients

(2014) Patricia Bourguignon et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Enhancement of Adaptive Immunity by the Human Vaccine Adjuvant AS01 Depends on Activated Dendritic Cells

(2014) Arnaud M. Didierlaurent et al.   JOURNAL OF IMMUNOLOGY

In search of a new paradigm for protective immunity to TB

(2014) Cláudio Nunes-Alves et al.   NATURE REVIEWS MICROBIOLOGY

Safety and immunogenicity of the M72/AS01 candidate tuberculosis vaccine when given as a booster to BCG in Gambian infants: An open-label randomized controlled trial

(2014) Olubukola T. Idoko et al.   TUBERCULOSIS

Induction and Regulation of T-Cell Immunity by the Novel Tuberculosis Vaccine M72/AS01 in South African Adults

(2013) Cheryl L. Day et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials

(2013) Punam Mangtani et al.   CLINICAL INFECTIOUS DISEASES

Systems approaches to studying the immune response in tuberculosis

(2013) Matthew Paul Reddoch Berry et al.   CURRENT OPINION IN IMMUNOLOGY

Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

(2013) Gerlinde Obermoser et al.   IMMUNITY

A Randomized, Controlled Dose-Finding Phase II Study of the M72/AS01 Candidate Tuberculosis Vaccine in Healthy PPD-Positive Adults

(2013) Jaime Montoya et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Tuberculosis biomarkers discovery: developments, needs, and challenges

(2013) Robert S Wallis et al.   LANCET INFECTIOUS DISEASES

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

(2013) Shuzhao Li et al.   NATURE IMMUNOLOGY

Genome-Wide Characterization of Transcriptional Patterns in High and Low Antibody Responders to Rubella Vaccination

(2013) Iana H. Haralambieva et al.   PLoS One

Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers

(2013) Chloe I. Bloom et al.   PLoS One

Systems biological approaches to measure and understand vaccine immunity in humans

(2013) Shuzhao Li et al.   SEMINARS IN IMMUNOLOGY

High-Resolution Temporal Response Patterns to Influenza Vaccine Reveal a Distinct Human Plasma Cell Gene Signature

(2013) Alicia D. Henn et al.   Scientific Reports

High-Dimensional Gene Expression Profiling Studies in High and Low Responders to Primary Smallpox Vaccination

(2012) Iana H. Haralambieva et al.   JOURNAL OF INFECTIOUS DISEASES

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

(2012) Chloe I. Bloom et al.   PLoS One

Merck Ad5/HIV induces broad innate immune activation that predicts CD8+ T-cell responses but is attenuated by preexisting Ad5 immunity

(2012) D. E. Zak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial

(2012) Isabel Leroux-Roels et al.   VACCINE

Recent clinical experience with vaccines using MPL- and QS-21-containing Adjuvant Systems

(2011) Nathalie Garçon et al.   Expert Review of Vaccines

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

Vaccine-induced anti-tuberculosis protective immunity in mice correlates with the magnitude and quality of multifunctional CD4 T cells

(2011) Steven C. Derrick et al.   VACCINE

Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

(2010) Benjamin M. N. Kagina et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human gene expression profiles of susceptibility and resistance in tuberculosis

(2010) J Maertzdorf et al.   GENES AND IMMUNITY

Expression of Genes Associated with Immunoproteasome Processing of Major Histocompatibility Complex Peptides Is Indicative of Protection with Adjuvanted RTS,S Malaria Vaccine

(2010) Maryanne T. Vahey et al.   JOURNAL OF INFECTIOUS DISEASES

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Spectrum of latent tuberculosis — existing tests cannot resolve the underlying phenotypes

(2010) Madhukar Pai   NATURE REVIEWS MICROBIOLOGY

LTBI: latent tuberculosis infection or lasting immune responses to M. tuberculosis? A TBNET consensus statement

(2009) U. Mack et al.   EUROPEAN RESPIRATORY JOURNAL

Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection

(2009) Kent E. Kester et al.   JOURNAL OF INFECTIOUS DISEASES

Eliminating latent tuberculosis

(2009) Douglas B. Young et al.   TRENDS IN MICROBIOLOGY

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Quality Assessment for Short Oligonucleotide Microarray Data

(2008) Julia Brettschneider et al.   TECHNOMETRICS