A Randomized, Controlled Dose-Finding Phase II Study of the M72/AS01 Candidate Tuberculosis Vaccine in Healthy PPD-Positive Adults

The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans

(2014) Kenneth Von Eschen et al.   Human vaccines & immunotherapeutics

A Phase IIa Trial of the New Tuberculosis Vaccine, MVA85A, in HIV- and/orMycobacterium tuberculosis–infected Adults

(2012) Thomas J. Scriba et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Importance of Adjuvant Formulation in the Development of a Tuberculosis Vaccine

(2012) S. L. Baldwin et al.   JOURNAL OF IMMUNOLOGY

The candidate tuberculosis vaccine Mtb72F/AS02 in PPD positive adults: A randomized controlled phase I/II study

(2012) François Spertini et al.   TUBERCULOSIS

Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial

(2012) Isabel Leroux-Roels et al.   VACCINE

Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go?

(2012) Tom H. M. Ottenhoff et al.   PLoS Pathogens

Recent clinical experience with vaccines using MPL- and QS-21-containing Adjuvant Systems

(2011) Nathalie Garçon et al.   Expert Review of Vaccines

Dose-Finding Study of the Novel Tuberculosis Vaccine, MVA85A, in Healthy BCG-Vaccinated Infants

(2011) Thomas J. Scriba et al.   JOURNAL OF INFECTIOUS DISEASES

A multistage tuberculosis vaccine that confers efficient protection before and after exposure

(2011) Claus Aagaard et al.   NATURE MEDICINE

BCG sub-strains induce variable protection against virulent pulmonary Mycobacterium tuberculosis infection, with the capacity to drive Th2 immunity

(2011) Andrew Keyser et al.   VACCINE

The Novel Tuberculosis Vaccine, AERAS-402, Induces Robust and Polyfunctional CD4+and CD8+T Cells in Adults

(2010) Brian Abel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

(2010) Benjamin M. N. Kagina et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evaluation of the Safety and Immunogenicity of Two Antigen Concentrations of the Mtb72F/AS02A Candidate Tuberculosis Vaccine in Purified Protein Derivative-Negative Adults

(2010) I. Leroux-Roels et al.   Clinical and Vaccine Immunology

Multifunctional CD4+ T cells correlate with active Mycobacterium tuberculosis infection

(2010) Nadia Caccamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

H5N1 Influenza Vaccine Formulated with AS03A Induces Strong Cross-Reactive and Polyfunctional CD4 T-Cell Responses

(2010) Philippe Moris et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Expanded Polyfunctional T Cell Response to Mycobacterial Antigens in TB Disease and Contraction Post-Treatment

(2010) James M. Young et al.   PLoS One

A Longitudinal Study of BCG Vaccination in Early Childhood: The Development of Innate and Adaptive Immune Responses

(2010) Yenny Djuardi et al.   PLoS One

Safety and Immunogenicity of a New Tuberculosis Vaccine, MVA85A, inMycobacterium tuberculosis–infected Individuals

(2009) Clare R. Sander et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The protective role of antibody responses duringMycobacterium tuberculosisinfection

(2009) F. Abebe et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The quest for biomarkers in tuberculosis

(2009) Shreemanta K. Parida et al.   DRUG DISCOVERY TODAY

Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells

(2009) Thomas J. Scriba et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Quality and Vaccine Efficacy of CD4+ T Cell Responses Directed to Dominant and Subdominant Epitopes in ESAT-6 from Mycobacterium tuberculosis

(2009) C. S. Aagaard et al.   JOURNAL OF IMMUNOLOGY

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

Distinct Differences in the Expansion and Phenotype of TB10.4 Specific CD8 and CD4 T Cells after Infection with Mycobacterium tuberculosis

(2009) Truc Thi Kim Thanh Hoang et al.   PLoS One

Protection and Polyfunctional T Cells Induced by Ag85B-TB10.4/IC31® against Mycobacterium tuberculosis Is Highly Dependent on the Antigen Dose

(2009) Claus Aagaard et al.   PLoS One

Complex cytokine profiles induced by BCG vaccination in UK infants

(2009) Maeve K. Lalor et al.   VACCINE

Persistence of the immune response induced by BCG vaccination

(2008) Rosemary E Weir et al.   BMC INFECTIOUS DISEASES

Mycobacterium tuberculosis-specific CD4+, IFNγ+, and TNFα+ multifunctional memory T cells coexpress GM-CSF

(2008) Henrik Mueller et al.   CYTOKINE

Standardization and optimization of multiparameter intracellular cytokine staining

(2008) Laurel Nomura et al.   CYTOMETRY PART A

Safety and Immunogenicity of a New Tuberculosis Vaccine, MVA85A, in Healthy Adults in South Africa

(2008) Tony Hawkridge et al.   JOURNAL OF INFECTIOUS DISEASES

Natural Variation in Immune Responses to Neonatal Mycobacterium bovis Bacillus Calmette-Guerin (BCG) Vaccination in a Cohort of Gambian Infants

(2008) Chris Finan et al.   PLoS One