Follicular Dendritic Cells of Lymph Nodes as Human Immunodeficiency Virus/Simian Immunodeficiency Virus Reservoirs and Insights on Cervical Lymph Node

Functional Meningeal Lymphatics and Cerebrospinal Fluid Outflow

(2018) Rajnish S. Dave et al.   Journal of Neuroimmune Pharmacology

CTLA-4 + PD-1 − Memory CD4 + T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

(2017) Colleen S. McGary et al.   IMMUNITY

FDC:TFH Interactions within Cervical Lymph Nodes of SIV-Infected Rhesus Macaques

(2017) Rajnish S. Dave et al.   Journal of Neuroimmune Pharmacology

Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1

(2017) Shannon M. Miller et al.   JOURNAL OF VIROLOGY

CXCR5-Dependent Entry of CD8 T Cells into Rhesus Macaque B-Cell Follicles Achieved through T-Cell Engineering

(2017) Victor I. Ayala et al.   JOURNAL OF VIROLOGY

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models

(2017) Chaoran Yin et al.   MOLECULAR THERAPY

Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys

(2017) Nicolas Huot et al.   NATURE MEDICINE

Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection

(2017) Geetha H. Mylvaganam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germinal Center Lymphocyte Ratios and Successful HIV Vaccines

(2017) Paula Gonzalez-Figueroa et al.   TRENDS IN MOLECULAR MEDICINE

Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

(2017) Qiaoli Ma et al.   Nature Communications

The Lymph Node in HIV Pathogenesis

(2017) Yiannis Dimopoulos et al.   Current HIV/AIDS Reports

Divergent Expression of CXCR5 and CCR5 on CD4+ T Cells and the Paradoxical Accumulation of T Follicular Helper Cells during HIV Infection

(2017) John Zaunders et al.   Frontiers in Immunology

HIV-1 and SIV Predominantly Use CCR5 Expressed on a Precursor Population to Establish Infection in T Follicular Helper Cells

(2017) Yin Xu et al.   Frontiers in Immunology

Vascular, glial, and lymphatic immune gateways of the central nervous system

(2016) Britta Engelhardt et al.   ACTA NEUROPATHOLOGICA

Potential of Radiation-Induced Cellular Stress for Reactivation of Latent HIV-1 and Killing of Infected Cells

(2016) Sergey Iordanskiy et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

A Drug-Free Zone—Lymph Nodes as a Safe Haven for HIV

(2016) Anna Licht et al.   Cell Host & Microbe

HIV and Tfh Cells: Circulating New Ideas to Identify and Protect

(2016) Ann Chahroudi et al.   IMMUNITY

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

(2016) Colin Havenar-Daughton et al.   JOURNAL OF IMMUNOLOGY

Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8 + Cells In Vivo

(2016) Shengbin Li et al.   JOURNAL OF VIROLOGY

Lymphatic Dissemination of Simian Immunodeficiency Virus after Penile Inoculation

(2016) Zhong-Min Ma et al.   JOURNAL OF VIROLOGY

CRISPR-mediated Activation of Latent HIV-1 Expression

(2016) Prajit Limsirichai et al.   MOLECULAR THERAPY

Erratum: Corrigendum: Structural and functional features of central nervous system lymphatic vessels

(2016) Antoine Louveau et al.   NATURE

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

(2016) Yew Ann Leong et al.   NATURE IMMUNOLOGY

Impaired B cells survival upon production of inflammatory cytokines by HIV-1 exposed follicular dendritic cells

(2016) Farideh Sabri et al.   Retrovirology

Sustained virologic control in SIV+ macaques after antiretroviral and  4 7 antibody therapy

(2016) S. N. Byrareddy et al.   SCIENCE

T FH in HIV Latency and as Sources of Replication-Competent Virus

(2016) Brodie Miles et al.   TRENDS IN MICROBIOLOGY

Impact of Chronic HIV/SIV Infection on T Follicular Helper Cell Subsets and Germinal Center Homeostasis

(2016) Stéphanie Graff-Dubois et al.   Frontiers in Immunology

Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing

(2016) Rafal Kaminski et al.   Scientific Reports

Dendritic cell type-specific HIV-1 activation in effector T cells

(2015) Renée M. van der Sluis et al.   AIDS

HIV Reservoir Dynamics in the Face of Highly Active Antiretroviral Therapy

(2015) Cecilia T. Costiniuk et al.   AIDS PATIENT CARE AND STDS

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus–Infected Rhesus Macaques May Contribute to Accumulation of TFHin Chronic Infection

(2015) Ankita Chowdhury et al.   JOURNAL OF IMMUNOLOGY

Persistent Simian Immunodeficiency Virus Infection Drives Differentiation, Aberrant Accumulation, and Latent Infection of Germinal Center Follicular T Helper Cells

(2015) Huanbin Xu et al.   JOURNAL OF VIROLOGY

Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy

(2015) Suresh Pallikkuth et al.   JOURNAL OF VIROLOGY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

(2015) Yoshinori Fukazawa et al.   NATURE MEDICINE

Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques

(2015) Philip J Santangelo et al.   NATURE METHODS

Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption

(2015) Meghan K. Rothenberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quality and quantity of T FH cells are critical for broad antibody development in SHIV AD8 infection

(2015) Takuya Yamamoto et al.   Science Translational Medicine

Revisiting the Mechanisms of CNS Immune Privilege

(2015) Antoine Louveau et al.   TRENDS IN IMMUNOLOGY

Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection

(2015) Brodie Miles et al.   Nature Communications

Dynamic models of viral replication and latency

(2015) Pejman Mohammadi et al.   Current Opinion in HIV and AIDS

CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs

(2015) Yonggang Zhang et al.   Scientific Reports

Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes

(2015) Balthasar A. Heesters et al.   PLoS Pathogens

Commentary: Structural and functional features of central nervous system lymphatic vessels

(2015) James J. Bradstreet et al.   Frontiers in Neuroscience

Monocytes Mediate HIV Neuropathogenesis: Mechanisms that Contribute to HIV Associated Neurocognitive Disorders

(2014) Dionna Williams et al.   CURRENT HIV RESEARCH

Immune cell trafficking from the brain maintains CNS immune tolerance

(2014) Mohammad G. Mohammad et al.   JOURNAL OF CLINICAL INVESTIGATION

HIV Type 1 (HIV-1) Proviral Reservoirs Decay Continuously Under Sustained Virologic Control in HIV-1–Infected Children Who Received Early Treatment

(2014) Katherine Luzuriaga et al.   JOURNAL OF INFECTIOUS DISEASES

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

(2014) Courtney V. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV cure research: Advances and prospects

(2014) Caroline P. Passaes et al.   VIROLOGY

Follicular dendritic cells: origin, function, and different disease-associated patterns

(2013) Sherif A. Rezk et al.   HUMAN PATHOLOGY

Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Antigen Binding and Activation

(2013) Balthasar A. Heesters et al.   IMMUNITY

Effect of morphine and SIV on dendritic cell trafficking into the central nervous system of rhesus macaques

(2013) Rebecca Hollenbach et al.   JOURNAL OF NEUROVIROLOGY

Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer

(2013) Lijun Yang et al.   Journal of Translational Medicine

Contribution of Follicular Dendritic Cells to Persistent HIV Viremia

(2013) J. Zhang et al.   JOURNAL OF VIROLOGY

Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques

(2013) Y. Xu et al.   JOURNAL OF VIROLOGY

Acute SIV Infection in Sooty Mangabey Monkeys Is Characterized by Rapid Virus Clearance from Lymph Nodes and Absence of Productive Infection in Germinal Centers

(2013) Amanda J. Martinot et al.   PLoS One

Follicular dendritic cells: origin, phenotype, and function in health and disease

(2013) Adriano Aguzzi et al.   TRENDS IN IMMUNOLOGY

CD4 T follicular helper cell dynamics during SIV infection

(2012) Constantinos Petrovas et al.   JOURNAL OF CLINICAL INVESTIGATION

Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood–brain barrier through paracellular transmigration and ERK activation

(2012) Divya Sagar et al.   Journal of Neuroinflammation

Follicular dendritic cells in health and disease

(2012) Mohey Eldin M. El Shikh et al.   Frontiers in Immunology

HIV Replication in CD4+ T Lymphocytes in the Presence and Absence of Follicular Dendritic Cells: Inhibition of Replication Mediated by  -1-Antitrypsin through Altered I B  Ubiquitination

(2011) X. Zhou et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of Dendritic Cell Trafficking Across the Blood–brain Barrier

(2011) Divya Sagar et al.   Journal of Neuroimmune Pharmacology

Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation

(2010) K. Allers et al.   BLOOD

Characterizing follicular dendritic cells: A progress report

(2010) Adriano Aguzzi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

History of viral suppression on combination antiretroviral therapy as a predictor of virological failure after a treatment change

(2010) J Reekie et al.   HIV MEDICINE

 4 1 Integrin Mediates the Recruitment of Immature Dendritic Cells across the Blood-Brain Barrier during Experimental Autoimmune Encephalomyelitis

(2010) P. Jain et al.   JOURNAL OF IMMUNOLOGY

Intracerebral Dendritic Cells Critically Modulate Encephalitogenic versus Regulatory Immune Responses in the CNS

(2009) A. L. Zozulya et al.   JOURNAL OF NEUROSCIENCE

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Recreational drug use and T lymphocyte subpopulations in HIV-uninfected and HIV-infected men

(2008) Chun Chao et al.   DRUG AND ALCOHOL DEPENDENCE

Factors associated with viral rebound among highly treatment-experienced HIV-positive patients who have achieved viral suppression

(2008) CJ Smith et al.   HIV MEDICINE

Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE

(2008) Marloes van Zwam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Follicular Dendritic Cells and Human Immunodeficiency Virus Type 1 Transcription in CD4+ T Cells

(2008) T. C. Thacker et al.   JOURNAL OF VIROLOGY

Characterization of the Follicular Dendritic Cell Reservoir of Human Immunodeficiency Virus Type 1

(2008) B. F. Keele et al.   JOURNAL OF VIROLOGY

Cerebrospinal Fluid Dendritic Cells Infiltrate the Brain Parenchyma and Target the Cervical Lymph Nodes under Neuroinflammatory Conditions

(2008) Eric Hatterer et al.   PLoS One

Follicular dendritic cell networks of primary follicles and germinal centers: Phenotype and function

(2008) Christopher D.C. Allen et al.   SEMINARS IN IMMUNOLOGY