Sparking Fire Under the Skin? Answers From the Association of Complement Genes With Pemphigus Foliaceus

Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering

(2017) Kenji Yoshida et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Cytokine and Chemokines Alterations in the Endemic Form of Pemphigus Foliaceus (Fogo Selvagem)

(2017) Rodolfo Pessato Timóteo et al.   Frontiers in Immunology

A 3′UTR polymorphism marks differential KLRG1 mRNA levels through disruption of a miR-584-5p binding site and associates with pemphigus foliaceus susceptibility

(2016) Gabriel A. Cipolla et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Structure-Function Relationships of Complement Receptor Type 2 (CR2; CD21)

(2016) Jonathan Paul Hannan   CURRENT PROTEIN & PEPTIDE SCIENCE

The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond

(2016) József Dobó et al.   IMMUNOLOGICAL REVIEWS

Complement in disease: a defence system turning offensive

(2016) Daniel Ricklin et al.   Nature Reviews Nephrology

Geographic variations in epidemiology of two autoimmune bullous diseases: pemphigus and bullous pemphigoid

(2015) Erkan Alpsoy et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Pemphigus is associated withKIR3DL2expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo

(2015) Danillo G. Augusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential gene expression levels might explain association of LAIR2 polymorphisms with pemphigus

(2015) Carolina Maciel Camargo et al.   HUMAN GENETICS

Update on fogo selvagem, an endemic form of pemphigus foliaceus

(2015) Valeria Aoki et al.   JOURNAL OF DERMATOLOGY

Monitoring and Cell-Specific Deletion of C5aR1 Using a Novel Floxed GFP-C5aR1 Reporter Knock-in Mouse

(2015) Christian M. Karsten et al.   JOURNAL OF IMMUNOLOGY

IgE Anti-LJM11 Sand Fly Salivary Antigen May Herald the Onset of Fogo Selvagem in Endemic Brazilian Regions

(2015) Ye Qian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Large-Scale Electron Microscopy Maps of Patient Skin and Mucosa Provide Insight into Pathogenesis of Blistering Diseases

(2015) Ena Sokol et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Lectin Pathway of Complement and Rheumatic Heart Disease

(2015) Marcia Holsbach Beltrame et al.   Frontiers in Pediatrics

Complement component C3 mediates Th1/Th17 polarization in human T-cell activation and cutaneous GVHD

(2014) Q Ma et al.   BONE MARROW TRANSPLANTATION

Genome-wide gene expression profiling reveals unsuspected molecular alterations in pemphigus foliaceus

(2014) Danielle Malheiros et al.   IMMUNOLOGY

Involvement of the Apoptotic Mechanism in Pemphigus Foliaceus Autoimmune Injury of the Skin

(2014) N. Li et al.   JOURNAL OF IMMUNOLOGY

No Evidence of Apoptotic Cells in Pemphigus Acantholysis

(2014) Ineke C. Janse et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

An Updated Analysis with 85,939 Samples Confirms the Association Between CR1 rs6656401 Polymorphism and Alzheimer’s Disease

(2014) Ning Shen et al.   MOLECULAR NEUROBIOLOGY

MASP-1 Induces a Unique Cytokine Pattern in Endothelial Cells: A Novel Link between Complement System and Neutrophil Granulocytes

(2014) Péter K. Jani et al.   PLoS One

Both qualitative and quantitative genetic variation of MHC class II molecules may influence susceptibility to autoimmune diseases: The case of endemic pemphigus foliaceus

(2013) Bruno Zagonel Piovezan et al.   HUMAN IMMUNOLOGY

S100A8-S100A9 Protein Complex Mediates Psoriasis by Regulating the Expression of Complement Factor C3

(2013) Helia B. Schonthaler et al.   IMMUNITY

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Lectin pathway of complement activation and relation with clinical complications in critically ill children

(2013) Catherine Ingels et al.   PEDIATRIC RESEARCH

Polymorphisms in the MASP1 Gene Are Associated with Serum Levels of MASP-1, MASP-3, and MAp44

(2013) Christian Gytz Ammitzbøll et al.   PLoS One

Ultrastructure of acantholysis in pemphigus foliaceus re-examined from the current perspective

(2012) G. van der Wier et al.   BRITISH JOURNAL OF DERMATOLOGY

Clinical and immunological profile of umbilical involvement in pemphigus vulgaris and pemphigus foliaceus

(2012) J. V. Oliveira Júnior et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseases

(2012) Christian M. Karsten et al.   IMMUNOBIOLOGY

Cutting Edge: Brazilian Pemphigus Foliaceus Anti-Desmoglein 1 Autoantibodies Cross-React with Sand Fly Salivary LJM11 Antigen

(2012) Y. Qian et al.   JOURNAL OF IMMUNOLOGY

Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function

(2012) S. E. Degn et al.   JOURNAL OF IMMUNOLOGY

IgG Autoantibody Response against Keratinocyte Cadherins in Endemic Pemphigus Foliaceus (Fogo Selvagem)

(2012) Gustavo Flores et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Activating KIR and HLA Bw4 Ligands Are Associated to Decreased Susceptibility to Pemphigus Foliaceus, an Autoimmune Blistering Skin Disease

(2012) Danillo G. Augusto et al.   PLoS One

The Epidermal Growth Factor-like Domain of CD93 Is a Potent Angiogenic Factor

(2012) Yuan-Chung Kao et al.   PLoS One

Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis

(2012) Krzysztof Kiryluk et al.   PLoS Genetics

Mannan-binding lectin and ficolin deposition in skin lesions of pemphigus

(2011) Iara Jose de Messias-Reason et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Pemphigus autoimmunity: Hypotheses and realities

(2011) Sergei A. Grando   AUTOIMMUNITY

Membrane attack by complement: the assembly and biology of terminal complement complexes

(2011) Cosmin A. Tegla et al.   IMMUNOLOGIC RESEARCH

Desmoglein as a Target in Skin Disease and Beyond

(2011) Masayuki Amagai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Polymorphisms in the 2q33 and 3q21 chromosome regions including T-cell coreceptor and ligand genes may influence susceptibility to pemphigus foliaceus

(2010) Ricardo Dalla-Costa et al.   HUMAN IMMUNOLOGY

IgE, IgM, and IgG4 Anti-Desmoglein 1 Autoantibody Profile in Endemic Pemphigus Foliaceus (Fogo Selvagem)

(2010) Ye Qian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Geoepidemiologic considerations of auto-immune pemphigus

(2009) N. Meyer et al.   AUTOIMMUNITY REVIEWS

TRAF1/C5polymorphism is not associated with pemphigus

(2009) K. Mejri et al.   BRITISH JOURNAL OF DERMATOLOGY

Individual and epistatic effects of genetic polymorphisms of B-cell co-stimulatory molecules on susceptibility to pemphigus foliaceus

(2009) D Malheiros et al.   GENES AND IMMUNITY

Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function

(2009) M. Megyeri et al.   JOURNAL OF IMMUNOLOGY

Autoantibodies in the Autoimmune Disease Pemphigus Foliaceus Induce Blistering via p38 Mitogen-Activated Protein Kinase-Dependent Signaling in the Skin

(2008) Paula Berkowitz et al.   AMERICAN JOURNAL OF PATHOLOGY

Circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease 2 in endemic pemphigus foliaceus

(2008) I. Messias-Reason et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Development of an IgG4-Based Predictor of Endemic Pemphigus Foliaceus (Fogo Selvagem)

(2008) Bahjat F. Qaqish et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Anti-desmoglein IgG autoantibodies in patients with pemphigus in remission

(2008) EJ Kwon et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Association of Systemic Lupus Erythematosus withC8orf13–BLKandITGAM–ITGAX

(2008) Geoffrey Hom et al.   NEW ENGLAND JOURNAL OF MEDICINE

The IgM Anti-Desmoglein 1 Response Distinguishes Brazilian Pemphigus Foliaceus (Fogo Selvagem) from Other Forms of Pemphigus

(2007) Luis A. Diaz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY