Symbicort® Maintenance and Reliever Therapy (SMART) and the evolution of asthma management within the GINA guidelines

Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study

(2017) Helen K Reddel et al.   LANCET

Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma

(2017) Parameswaran Nair et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tezepelumab in Adults with Uncontrolled Asthma

(2017) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given ‘as needed’ in mild asthma: study protocols for two randomised controlled trials

(2017) Paul M. O’Byrne et al.   Trials

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story

(2016) J. Bousquet et al.   ALLERGY

Real-life effectiveness of budesonide/formoterol therapy in asthma: A subanalysis of the SMARTASIA study

(2016) Jiangtao Lin et al.   ALLERGY AND ASTHMA PROCEEDINGS

Description of a randomised controlled trial of inhaled corticosteroid/fast-onset LABA reliever therapy in mild asthma

(2016) Richard Beasley et al.   EUROPEAN RESPIRATORY JOURNAL

A Critical Evaluation of Anti-IL-13 and Anti-IL-4 Strategies in Severe Asthma

(2016) Diego Bagnasco et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised, multicentre, placebo-controlled phase 3 trial

(2016) Eugene R Bleecker et al.   LANCET

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

(2016) Sally Wenzel et al.   LANCET

Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial

(2016) J Mark FitzGerald et al.   LANCET

Two Phase II randomized trials on the CRTh2 antagonist AZD1981 in adults with asthma

(2016) Piotr Kuna et al.   Drug Design Development and Therapy

Fevipiprant, a prostaglandin D 2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial

(2016) Sherif Gonem et al.   Lancet Respiratory Medicine

Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials

(2016) Nicola A Hanania et al.   Lancet Respiratory Medicine

The frequency of, and adherence to, single maintenance and reliever therapy instructions in asthma: a descriptive analysis

(2016) Rachael L DiSantostefano et al.   npj Primary Care Respiratory Medicine

Asthma Worsenings: Approaches to Prevention and Management from the Asthma Worsenings Working Group

(2016) Meyer Balter et al.   Canadian Respiratory Journal

Real-life use of budesonide/formoterol in clinical practice: a 12-month follow-up assessment in a multi-national study of asthma patients established on single-inhaler maintenance and reliever therapy

(2015) Björn Ställberg et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Allergen-Induced Asthmatic Responses Modified by a GATA3-Specific DNAzyme

(2015) Norbert Krug et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of BI 671800, an oral CRTH2 antagonist, in poorly controlled asthma as sole controller and in the presence of inhaled corticosteroid treatment

(2015) Ian P. Hall et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

The effect of fluticasone furoate/umeclidinium in adult patients with asthma: A randomized, dose-ranging study

(2015) Laurie A. Lee et al.   RESPIRATORY MEDICINE

Erratum: Asthma attacks: how can we reduce the risks?

(2015) Mike Thomas et al.   npj Primary Care Respiratory Medicine

The use of β2-agonist therapy before hospital attendance for severe asthma exacerbations: a post-hoc analysis

(2015) Mitesh Patel et al.   npj Primary Care Respiratory Medicine

The GINA asthma strategy report: what’s new for primary care?

(2015) Helen K Reddel et al.   npj Primary Care Respiratory Medicine

Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses

(2014) Gail M. Gauvreau et al.   NEW ENGLAND JOURNAL OF MEDICINE

Asthma control and management in 8,000 European patients: the REcognise Asthma and LInk to Symptoms and Experience (REALISE) survey

(2014) David Price et al.   npj Primary Care Respiratory Medicine

Combination corticosteroid/β-agonist inhaler as reliever therapy: A solution for intermittent and mild asthma?

(2013) Richard Beasley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma control: importance of compliance and inhaler technique assessments

(2013) Sawsan Baddar et al.   JOURNAL OF ASTHMA

Real-life effectiveness of budesonide/formoterol maintenance and reliever therapy in asthma patients across Asia: SMARTASIA study

(2013) Nanshan Zhong et al.   BMC Pulmonary Medicine

Efficacy and safety of maintenance and reliever combination budesonide–formoterol inhaler in patients with asthma at risk of severe exacerbations: a randomised controlled trial

(2013) Mitesh Patel et al.   Lancet Respiratory Medicine

Beclometasone–formoterol as maintenance and reliever treatment in patients with asthma: a double-blind, randomised controlled trial

(2013) Alberto Papi et al.   Lancet Respiratory Medicine

The clinical impact of single inhaler therapy in asthma

(2012) K. Czarnecka et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Adherence

(2012) Louis-Philippe Boulet et al.   CLINICS IN CHEST MEDICINE

The effect of budesonide/formoterol maintenance and reliever therapy on the risk of severe asthma exacerbations following episodes of high reliever use: an exploratory analysis of two randomised, controlled studies with comparisons to standard therapy

(2012) Roland Buhl et al.   RESPIRATORY RESEARCH

Towards the Grade of Recommendations, Assessment, Development and Evaluation system

(2011) Fulvio Braido et al.   Current Opinion in Allergy and Clinical Immunology

User Error With Diskus and Turbuhaler by Asthma Patients and Pharmacists in Jordan and Australia

(2011) I. A. Basheti et al.   Respiratory Care

Audit of budesonide/formoterol prescribing for asthma in community pharmacy in the UK

(2011) Anne C. Boyter et al.   RESPIRATORY MEDICINE

Comparing asthma treatment in elderly versus younger patients

(2011) J. Haughney et al.   RESPIRATORY MEDICINE

Inhaler mishandling remains common in real life and is associated with reduced disease control

(2011) Andrea S. Melani et al.   RESPIRATORY MEDICINE

Asthma control in patients receiving inhaled corticosteroid and long-acting beta2-agonist fixed combinations. A real-life study comparing dry powder inhalers and a pressurized metered dose inhaler extrafine formulation

(2011) Veronika Müller et al.   BMC Pulmonary Medicine

Budesonide/formoterol maintenance and reliever therapy in primary care asthma management: effects on bronchial hyperresponsiveness and asthma control

(2011) Roland A Riemersma et al.   Primary Care Respiratory Journal

Comparison of two twice-daily doses of budesonide/formoterol maintenance and reliever therapy

(2010) M. Aubier et al.   EUROPEAN RESPIRATORY JOURNAL

Overall asthma control: The relationship between current control and future risk

(2010) Eric D. Bateman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations

(2009) Helen K. Reddel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A comparison of budesonide/formoterol maintenance and reliever therapy vs. conventional best practice in asthma management

(2009) R. Louis et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Budesonide/formoterol maintenance and reliever therapy versus conventional best practice

(2009) Pascal Demoly et al.   RESPIRATORY MEDICINE

Safety of budesonide/formoterol maintenance and reliever therapy in asthma trials

(2009) Malcolm R. Sears et al.   RESPIRATORY MEDICINE

Budesonide/formoterol maintenance and reliever therapy: impact on airway inflammation in asthma

(2008) M. R. Sears et al.   EUROPEAN RESPIRATORY JOURNAL

Poor adherence with inhaled corticosteroids for asthma: can using a single inhaler containing budesonide and formoterol help?

(2007) Milind P Sovani et al.   BRITISH JOURNAL OF GENERAL PRACTICE