Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story

AIRWAYS-ICPs (European Innovation Partnership on Active and Healthy Ageing) from concept to implementation

(2016) Jean Bousquet et al.   EUROPEAN RESPIRATORY JOURNAL

Sensitization to cat and dog allergen molecules in childhood and prediction of symptoms of cat and dog allergy in adolescence: A BAMSE/MeDALL study

(2016) Anna Asarnoj et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis

(2015) J. Bousquet et al.   ALLERGY

A novel, dual cytokine-secretion assay for the purification of human Th22 cells that do not co-produce IL-17A

(2015) M. Wawrzyniak et al.   ALLERGY

Phenotyping asthma, rhinitis and eczema in MeDALL population-based birth cohorts: an allergic comorbidity cluster

(2015) J. Garcia-Aymerich et al.   ALLERGY

IgE antibodies in relation to prevalence and multimorbidity of eczema, asthma, and rhinitis from birth to adolescence

(2015) N. Ballardini et al.   ALLERGY

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation

(2015) J. Bousquet et al.   ALLERGY

Interleukin-21-Producing CD4+ T Cells Promote Type 2 Immunity to House Dust Mites

(2015) Jonathan M. Coquet et al.   IMMUNITY

Integrated Allergy and Asthma Prevention and Care: Report of the MeDALL/AIRWAYS ICPs Meeting at the Ministry of Health and Care Services, Oslo, Norway

(2015) Karin C. Lødrup Carlsen et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Clinical Relevance of Cluster Analysis in Phenotyping Allergic Rhinitis in a Real-Life Study

(2015) Philippe Jean Bousquet et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Systematic Review on the Definition of Allergic Diseases in Children: The MeDALL Study

(2015) Mariona Pinart et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Fusing Randomized Trials With Big Data

(2015) Derek C. Angus   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CpG-DNA enhances the tight junction integrity of the bronchial epithelial cell barrier

(2015) Terufumi Kubo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T-cell regulation during viral and nonviral asthma exacerbations

(2015) Agnieszka S. Wegrzyn et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early childhood IgE reactivity to pathogenesis-related class 10 proteins predicts allergic rhinitis in adolescence

(2015) Marit Westman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-10–overexpressing B cells regulate innate and adaptive immune responses

(2015) Barbara Stanic et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The use of the MeDALL-chip to assess IgE sensitization: a new diagnostic tool for allergic disease?

(2015) Ingebjørg Skrindo et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Allergic multimorbidity of asthma, rhinitis and eczema over 20 years in the German birth cohort MAS

(2015) Hannah Gough et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Characterization of Rhinitis According to the Asthma Status in Adults Using an Unsupervised Approach in the EGEA Study

(2015) Emilie Burte et al.   PLoS One

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

(2015) M. J. Schuijs et al.   SCIENCE

Developmental determinants in non-communicable chronic diseases and ageing

(2015) J Bousquet et al.   THORAX

Development of senioral policy in Poland – analysis

(2015) B. Samoliński et al.   European Geriatric Medicine

Childhood asthma prediction models: a systematic review

(2015) Henriette A Smit et al.   Lancet Respiratory Medicine

Exposure to air pollution and development of asthma and rhinoconjunctivitis throughout childhood and adolescence: a population-based birth cohort study

(2015) Ulrike Gehring et al.   Lancet Respiratory Medicine

Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study

(2015) Stefano Guerra et al.   Lancet Respiratory Medicine

Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study

(2015) David B Price et al.   Lancet Respiratory Medicine

Allergen Immunotherapy (AIT): a prototype of Precision Medicine

(2015) GW Canonica et al.   World Allergy Organization Journal

The locusC11orf30increases susceptibility to poly-sensitization

(2014) A. F. S. Amaral et al.   ALLERGY

Trajectories of Lung Function during Childhood

(2014) Danielle C. M. Belgrave et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Systems Medicine Approaches for the Definition of Complex Phenotypes in Chronic Diseases and Ageing. From Concept to Implementation and Policies

(2014) Jean Bousquet et al.   CURRENT PHARMACEUTICAL DESIGN

Integrated care pathways for airway diseases (AIRWAYS-ICPs)

(2014) J. Bousquet et al.   EUROPEAN RESPIRATORY JOURNAL

A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project

(2014) Anna Mölter et al.   EUROPEAN RESPIRATORY JOURNAL

Regulatory T cells and immune regulation of allergic diseases: roles of IL-10 and TGF-β

(2014) O Palomares et al.   GENES AND IMMUNITY

The Development of the MeDALL Core Questionnaires for a Harmonized Follow-Up Assessment of Eleven European Birth Cohorts on Asthma and Allergies

(2014) Cynthia Hohmann et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Associations between particulate matter elements and early-life pneumonia in seven birth cohorts: Results from the ESCAPE and TRANSPHORM projects

(2014) Elaine Fuertes et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Birth cohorts in asthma and allergic diseases: Report of a NIAID/NHLBI/MeDALL joint workshop

(2014) Jean Bousquet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

(2014) Manuel A.R. Ferreira et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Natural history of allergic sensitization in infants with early-onset atopic dermatitis: results from ORCA Study

(2014) Jocelyne Just et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

MACVIA-LR, Reference site of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) in Languedoc Roussillon

(2014) J. Bousquet et al.   European Geriatric Medicine

The European Innovation Partnership on Active and Healthy Ageing: The European geriatric medicine introduces the EIP on AHA column

(2014) J. Bousquet et al.   European Geriatric Medicine

Comorbidity of eczema, rhinitis, and asthma in IgE-sensitised and non-IgE-sensitised children in MeDALL: a population-based cohort study

(2014) Mariona Pinart et al.   Lancet Respiratory Medicine

Impact of early diagnosis and control of chronic respiratory diseases on active and healthy ageing

(2013) J. Bousquet et al.   ALLERGY

IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses

(2013) Willem van de Veen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Advances in allergen-microarray technology for diagnosis and monitoring of allergy: The MeDALL allergen-chip

(2013) Christian Lupinek et al.   METHODS

Communication of results and disclosure of incidental findings in longitudinal paediatric research

(2013) Velizara Anastasova et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Ambient air pollution and low birthweight: a European cohort study (ESCAPE)

(2013) Marie Pedersen et al.   Lancet Respiratory Medicine

Prevention and control of childhood asthma and allergy in the EU from the public health point of view: Polish Presidency of the European Union

(2012) B. Samoliński et al.   ALLERGY

Development of Land Use Regression Models for PM2.5, PM2.5 Absorbance, PM10 and PMcoarse in 20 European Study Areas; Results of the ESCAPE Project

(2012) Marloes Eeftens et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Two novel, severe asthma phenotypes identified during childhood using a clustering approach

(2012) Jocelyne Just et al.   EUROPEAN RESPIRATORY JOURNAL

Regulatory cells in allergen-specific immunotherapy

(2012) Michael B Soyka et al.   Immunotherapy

Pooling Birth Cohorts in Allergy and Asthma: European Union-Funded Initiatives – A MeDALL, CHICOS, ENRIECO, and GA2LEN Joint Paper

(2012) Jean Bousquet et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Cohort Profile: The Born in Bradford multi-ethnic family cohort study

(2012) J. Wright et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The broad spectrum of interepithelial junctions in skin and lung

(2012) Jeannette I. Kast et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Risk factors and characteristics of respiratory and allergic phenotypes in early childhood

(2012) Marie Herr et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: A Mechanisms of the Development of Allergy (MeDALL) Seminar

(2012) Josep M. Antó et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Novel severe wheezy young children phenotypes: Boys atopic multiple-trigger and girls nonatopic uncontrolled wheeze

(2012) Jocelyne Just et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Triggering of specific Toll-like receptors and proinflammatory cytokines breaks allergen-specific T-cell tolerance in human tonsils and peripheral blood

(2012) Umut Can Kücüksezer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Council of the European Union conclusions on chronic respiratory diseases in children

(2012) Bolesław Samoliński et al.   LANCET

MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine

(2011) J. Bousquet et al.   ALLERGY

Knowledge management for Systems Biology a general and visually driven framework applied to translational medicine

(2011) Dieter Maier et al.   BMC Systems Biology

Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance

(2011) Oscar Palomares et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Systems medicine and integrated care to combat chronic noncommunicable diseases

(2011) Jean Bousquet et al.   Genome Medicine

Prioritised research agenda for prevention and control of chronic respiratory diseases

(2010) J. Bousquet et al.   EUROPEAN RESPIRATORY JOURNAL

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

(2010) Jean Bousquet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

GA2LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma ‘epidemic’

(2009) J. Bousquet et al.   ALLERGY

Metabolic Syndrome in Early Pregnancy and Risk of Preterm Birth

(2009) Leda Chatzi et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Maternal Personal Exposure to Airborne Benzene and Intrauterine Growth

(2009) Rémy Slama et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Association between GIS-Based Exposure to Urban Air Pollution during Pregnancy and Birth Weight in the INMA Sabadell Cohort

(2009) Inmaculada Aguilera et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohort

(2009) Heidi Sucharew et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Finnish Allergy Programme 2008–2018 – time to act and change the course

(2008) T. Haahtela et al.   ALLERGY

Born in Bradford, a cohort study of babies born in Bradford, and their parents: Protocol for the recruitment phase

(2008) Pauline Raynor et al.   BMC PUBLIC HEALTH

Tracing Biological Collections

(2008) Francine Kauffmann et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Bronchial obstructive phenotypes in the first year of life among Paris birth cohort infants

(2008) Bénédicte Clarisse et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY