18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways
出版年份 2018 全文链接
标题
18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-06-20
DOI
10.3389/fphar.2018.00647
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structure-based development of an osteoprotegerin-like glycopeptide that blocks RANKL/RANK interactions and reduces ovariectomy-induced bone loss in mice
- (2018) Chao Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis
- (2018) Abhishek Chandra et al. FASEB JOURNAL
- A Matrine Derivative M54 Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Targeting Ribosomal Protein S5
- (2018) Zhi Xin et al. Frontiers in Pharmacology
- 18β-Glycyrrhetinic acid, the major bioactive component of Glycyrrhizae Radix, attenuates airway inflammation by modulating Th2 cytokines, GATA-3, STAT6, and Foxp3 transcription factors in an asthmatic mouse model
- (2017) Seung-Hyung Kim et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Enzyme replacement prevents neonatal death, liver damage, and osteoporosis in murine homocystinuria
- (2017) Tomas Majtan et al. FASEB JOURNAL
- Declining histone acetyltransferase GCN5 represses BMSC-mediated angiogenesis during osteoporosis
- (2017) Huan Jing et al. FASEB JOURNAL
- RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice
- (2017) Hiroyuki Kanzaki et al. FASEB JOURNAL
- Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis
- (2017) Xiao Chen et al. FASEB JOURNAL
- Anti-inflammatory and hepatoprotective effects of glycyrrhetinic acid on CCl 4 -induced damage in precision-cut liver slices from Jian carp ( Cyprinus carpio var . jian) through inhibition of the nf-kƁ pathway
- (2017) Liping Cao et al. FISH & SHELLFISH IMMUNOLOGY
- Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
- (2017) Genling Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- 18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration
- (2017) Saisai Wang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Glycyrrhetinic acid-modified TPGS polymeric micelles for hepatocellular carcinoma-targeted therapy
- (2017) Xiumei Zhu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Addressing the Crisis in the Treatment of Osteoporosis: Better Paths Forward
- (2017) William V Stoecker et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Primary Osteoporosis Is Not Reflected by Disease-Specific DNA Methylation or Accelerated Epigenetic Age in Blood
- (2017) Eduardo Fernandez-Rebollo et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Prevalence of Osteoporosis and Low Bone Mass Among Puerto Rican Older Adults
- (2017) Sabrina E Noel et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Comparative Analysis of the Radiology of Osteoporotic Vertebral Fractures in Women and Men: Cross-Sectional and Longitudinal Observations from the Canadian Multicentre Osteoporosis Study (CaMos)
- (2017) Brian C Lentle et al. JOURNAL OF BONE AND MINERAL RESEARCH
- 18α-Glycyrrhetinic acid monoglucuronide as an anti-inflammatory agent through suppression of the NF-κB and MAPK signaling pathway
- (2017) Bo Li et al. MedChemComm
- Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis
- (2017) Xiao Chen et al. Cell Death & Disease
- Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway
- (2017) Mengrui Wu et al. Nature Communications
- The Optimal Duration of PTH(1–34) Infusion Is One Hour per Day to Increase Bone Mass in Rats
- (2016) Masaru Shimizu et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Prevalence of osteoporosis in China: a meta-analysis and systematic review
- (2016) Peng Chen et al. BMC PUBLIC HEALTH
- Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease
- (2016) Chang Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dedicated Perioperative Hip Fracture Comanagement Programs are Cost-effective in High-volume Centers: An Economic Analysis
- (2015) Eric Swart et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- Glycyrrhizic acid attenuates stem cell-like phenotypes of human dermal papilla cells
- (2015) Chayanin Kiratipaiboon et al. PHYTOMEDICINE
- Induction of osteoclast progenitors in inflammatory conditions: key to bone destruction in arthritis
- (2014) Alan Šućur et al. INTERNATIONAL ORTHOPAEDICS
- Delphinidin, One of the Major Anthocyanidins, Prevents Bone Loss through the Inhibition of Excessive Osteoclastogenesis in Osteoporosis Model Mice
- (2014) Sawako Moriwaki et al. PLoS One
- Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling
- (2013) Fredrik Strålberg et al. FASEB JOURNAL
- Redundant miR-3077-5p and miR-705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow
- (2013) L Liao et al. Cell Death & Disease
- Adverse Reactions and Drug–Drug Interactions in the Management of Women with Postmenopausal Osteoporosis
- (2011) René Rizzoli et al. CALCIFIED TISSUE INTERNATIONAL
- Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1
- (2011) Sung-Yong Hwang et al. FASEB JOURNAL
- Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways
- (2010) Chenghai Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone
- (2010) Jeffry S Nyman et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Diphenylhydantoin Inhibits Osteoclast Differentiation and Function Through Suppression of NFATc1 Signaling
- (2009) Masanori Koide et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Prevention of free fatty acid-induced hepatic lipotoxicity by 18β-glycyrrhetinic acid through lysosomal and mitochondrial pathways
- (2008) Xudong Wu et al. HEPATOLOGY
- RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice
- (2008) Sergio Vaira et al. JOURNAL OF CLINICAL INVESTIGATION
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started