Epithelial–mesenchymal transition in lung development and disease: does it exist and is it important?

Prostacyclin Inhibits Non-Small Cell Lung Cancer Growth by a Frizzled 9-Dependent Pathway That Is Blocked by Secreted Frizzled-Related Protein 1

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Origin and function of myofibroblasts in kidney fibrosis

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Down-Regulation of Canonical and Up-Regulation of Non-Canonical Wnt Signalling in the Carcinogenic Process of Squamous Cell Lung Carcinoma

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The role of uPAR in epithelial-mesenchymal transition in small airway epithelium of patients with chronic obstructive pulmonary disease

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Pirfenidone for IPF: pro/con debate; the ‘con’ viewpoint

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Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease

(2013) Irene H Heijink et al.   THORAX

Epithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smoke

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Nicotine-induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells

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Regenerative activity of the lung after epithelial injury

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EMT in carcinoma progression and dissemination: Facts, unanswered questions, and clinical considerations

(2012) Jeremy Bastid   CANCER AND METASTASIS REVIEWS

An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

(2012) L. A. Byers et al.   CLINICAL CANCER RESEARCH

Noncanonical WNT-5A signaling regulates TGF-β-induced extracellular matrix production by airway smooth muscle cells

(2012) Kuldeep Kumawat et al.   FASEB JOURNAL

What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis

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Targeting TGFβ superfamily ligand accessory proteins as novel therapeutics for chronic lung disorders

(2012) David C. Budd et al.   PHARMACOLOGY & THERAPEUTICS

A comparison of epithelial-to-mesenchymal transition and re-epithelialization

(2012) Philip L. Leopold et al.   SEMINARS IN CANCER BIOLOGY

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis

(2011) Harold A. Chapman   Annual Review of Physiology

The EMT regulator slug and lung carcinogenesis

(2011) J.-Y. Shih et al.   CARCINOGENESIS

The potential use of tyrosine kinase inhibitors in severe asthma

(2011) Vamsi P. Guntur et al.   Current Opinion in Allergy and Clinical Immunology

Characterization of fibroblasts recruited from bone marrow-derived precursor in neonatal bronchopulmonary dysplasia mice

(2011) Chun Deng et al.   JOURNAL OF APPLIED PHYSIOLOGY

Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection

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Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer

(2011) Matthew G. Krebs et al.   JOURNAL OF CLINICAL ONCOLOGY

Scar wars: mapping the fate of epithelial–mesenchymal–myofibroblast transition

(2011) Susan E. Quaggin et al.   KIDNEY INTERNATIONAL

Incomplete expression of epithelial–mesenchymal transition markers in idiopathic pulmonary fibrosis

(2011) Patrizia Morbini et al.   PATHOLOGY RESEARCH AND PRACTICE

Chronic Respiratory Aeroallergen Exposure in Mice Induces Epithelial-Mesenchymal Transition in the Large Airways

(2011) Jill R. Johnson et al.   PLoS One

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thorax in focus: chronic obstructive pulmonary disease

(2011) David B Hodgson et al.   THORAX

Blockade of the Wnt/β-Catenin Pathway Attenuates Bleomycin-Induced Pulmonary Fibrosis

(2011) Tae Hyung Kim et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis

(2010) Amber L. Degryse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An Essential Role for Resident Fibroblasts in Experimental Lung Fibrosis Is Defined by Lineage-Specific Deletion of High-Affinity Type II Transforming Growth Factor β Receptor

(2010) Rachel K. Hoyles et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Preoperative Circulating Tumor Cell Detection Using the Isolation by Size of Epithelial Tumor Cell Method for Patients with Lung Cancer Is a New Prognostic Biomarker

(2010) V. Hofman et al.   CLINICAL CANCER RESEARCH

Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development

(2010) Edward E. Morrisey et al.   DEVELOPMENTAL CELL

Chromosome 4q31 locus in COPD is also associated with lung cancer

(2010) R. P. Young et al.   EUROPEAN RESPIRATORY JOURNAL

Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway

(2010) L. A. Borthwick et al.   EUROPEAN RESPIRATORY JOURNAL

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

(2010) M. Morimoto et al.   JOURNAL OF CELL SCIENCE

Immunosuppression-induced bronchial epithelial–mesenchymal transition: A potential contributor to obliterative bronchiolitis

(2010) Valerie M. Felton et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

(2010) W. R. Henderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease

(2010) Sukhwinder S. SOHAL et al.   RESPIROLOGY

Altered matrix production in the distal airways of individuals with asthma

(2010) K. Nihlberg et al.   THORAX

Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1

(2009) Guofei Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Induction of Epithelial–Mesenchymal Transition in Primary Airway Epithelial Cells from Patients with Asthma by Transforming Growth Factor-β1

(2009) Tillie-Louise Hackett et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis

(2009) Harikrishna Tanjore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

House Dust Mite–Promoted Epithelial-to-Mesenchymal Transition in Human Bronchial Epithelium

(2009) Irene H. Heijink et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Posttransplant Bronchiolitis Obliterans Syndrome Is Associated with Bronchial Epithelial to Mesenchymal Transition

(2009) S. Hodge et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Collective Cell Migration

(2009) Pernille Rørth   Annual Review of Cell and Developmental Biology

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration

(2009) Deborah J. Andrew et al.   DEVELOPMENTAL BIOLOGY

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

EMT: When epithelial cells decide to become mesenchymal-like cells

(2009) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

Epithelial–mesenchymal transition in human lungs with usual interstitial pneumonia: Quantitative immunohistochemistry

(2009) Taishi Harada et al.   PATHOLOGY INTERNATIONAL

Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation

(2009) L A Borthwick et al.   THORAX

SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis

(2009) A Jayachandran et al.   THORAX

Dual-immunohistochemistry provides little evidence for epithelial–mesenchymal transition in pulmonary fibrosis

(2008) Mizuho Yamada et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

(2008) Melanie Königshoff et al.   PLoS One

Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development

(2008) J. Que et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGFβ stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling

(2007) Genevieve A. Secker et al.   EXPERIMENTAL CELL RESEARCH

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY