Selective Histone Deacetylase 6 Inhibitor 23BB Alleviated Rhabdomyolysis-Induced Acute Kidney Injury by Regulating Endoplasmic Reticulum Stress and Apoptosis

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice

(2016) Jie Ran et al.   Oncotarget

Rhabdomyolysis induced AKI via the regulation of endoplasmic reticulum stress and oxidative stress in PTECs

(2016) Yuying Feng et al.   RSC Advances

Acetylation modification regulates GRP78 secretion in colon cancer cells

(2016) Zongwei Li et al.   Scientific Reports

Mechanisms of apoptosis

(2015) M. A. Savitskaya et al.   BIOCHEMISTRY-MOSCOW

Endoplasmic reticulum stress in kidney function and disease

(2015) Mai Taniguchi et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer

(2015) Zhuang Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression

(2015) M. A. Venkatachalam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Apoptosis, autophagy, necroptosis, and cancer metastasis

(2015) Zhenyi Su et al.   Molecular Cancer

Autophagy promotes apoptosis of mesenchymal stem cells under inflammatory microenvironment

(2015) Shipeng Dang et al.   Stem Cell Research & Therapy

Treatment of chronic kidney diseases with histone deacetylase inhibitors

(2015) Na Liu et al.   Frontiers in Physiology

Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism

(2014) Kwai Fung Hui et al.   INTERNATIONAL JOURNAL OF CANCER

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Histone deacetylase inhibitors: a potential epigenetic treatment for Duchenne muscular dystrophy

(2014) Silvia Consalvi et al.   Epigenomics

Combined treatment with SAHA, bortezomib, and clarithromycin for concomitant targeting of aggresome formation and intracellular proteolytic pathways enhances ER stress-mediated cell death in breast cancer cells

(2013) Seiichiro Komatsu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Amelioration of rhabdomyolysis-induced renal mitochondrial injury and apoptosis through suppression of Drp-1 translocation

(2013) Wan-Xin Tang et al.   JOURNAL OF NEPHROLOGY

Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response

(2012) Soumen Kahali et al.   FASEB JOURNAL

Stress management at the ER: Regulators of ER stress-induced apoptosis

(2012) Adrienne M. Gorman et al.   PHARMACOLOGY & THERAPEUTICS

Apoptosis and acute kidney injury

(2011) Andrea Havasi et al.   KIDNEY INTERNATIONAL

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

Regulation of apoptosis-associated genes by histone deacetylase inhibitors: implications in cancer therapy

(2010) Ali R. Jazirehi   ANTI-CANCER DRUGS

Rhabdomyolysis and Acute Kidney Injury

(2009) Xavier Bosch et al.   NEW ENGLAND JOURNAL OF MEDICINE

The syndrome of rhabdomyolysis: Complications and treatment

(2008) Yiannis S. Chatzizisis et al.   European Journal of Internal Medicine

Induction of Apoptosis in Renal Tubular Cells by Histone Deacetylase Inhibitors, a Family of Anticancer Agents

(2008) G. Dong et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY