Histone deacetylase inhibitors: a potential epigenetic treatment for Duchenne muscular dystrophy

HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles

(2014) V. Saccone et al.   GENES & DEVELOPMENT

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16

(2013) Hang Yin et al.   Cell Metabolism

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis

(2013) A Hongjun Wang et al.   EMBO JOURNAL

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

(2013) Chiara Mozzetta et al.   EMBO Molecular Medicine

Cellular dynamics in the muscle satellite cell niche

(2013) C Florian Bentzinger et al.   EMBO REPORTS

Repair or replace? Exploiting novel gene and cell therapy strategies for muscular dystrophies

(2013) Sara Benedetti et al.   FEBS Journal

Tissue-resident mesenchymal stem/progenitor cells in skeletal muscle: collaborators or saboteurs?

(2013) Robert N. Judson et al.   FEBS Journal

Epigenetic control of skeletal muscle regeneration

(2013) Lorenzo Giordani et al.   FEBS Journal

Muscular dystrophies

(2013) Eugenio Mercuri et al.   LANCET

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

(2013) Haruya Ohno et al.   NATURE

Muscle Side Population Cells from Dystrophic or Injured Muscle Adopt a Fibro-Adipogenic Fate

(2013) Christopher M. Penton et al.   PLoS One

Chromatin Modifications as Determinants of Muscle Stem Cell Quiescence and Chronological Aging

(2013) Ling Liu et al.   Cell Reports

Tissue-Specific Stem Cells: Lessons from the Skeletal Muscle Satellite Cell

(2012) Andrew S. Brack et al.   Cell Stem Cell

Pharmacologically Targeting the Primary Defect and Downstream Pathology in Duchenne Muscular Dystrophy

(2012) Rebecca J. Fairclough et al.   CURRENT GENE THERAPY

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

Lineage tracing and genetic ablation of ADAM12+ perivascular cells identify a major source of profibrotic cells during acute tissue injury

(2012) Sophie Dulauroy et al.   NATURE MEDICINE

Epigenetic protein families: a new frontier for drug discovery

(2012) Cheryl H. Arrowsmith et al.   NATURE REVIEWS DRUG DISCOVERY

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation

(2012) B. M. T. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis

(2011) Jelena Vojinovic et al.   ARTHRITIS AND RHEUMATISM

Selective control ofPax7expression by TNF-activated p38α/polycomb repressive complex 2 (PRC2) signaling during muscle satellite cell differentiation

(2011) Chiara Mozzetta et al.   CELL CYCLE

Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex

(2011) Sonia V Forcales et al.   EMBO JOURNAL

Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells

(2011) A. H. Juan et al.   GENES & DEVELOPMENT

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Unknown

(2011) Silvia Consalvi et al.   MOLECULAR MEDICINE

Unknown

(2011) Antonio Furlan et al.   MOLECULAR MEDICINE

Bmi1 Is Expressed in Postnatal Myogenic Satellite Cells, Controls Their Maintenance and Plays an Essential Role in Repeated Muscle Regeneration

(2011) Lesley G. Robson et al.   PLoS One

Genome-wide remodeling of the epigenetic landscape during myogenic differentiation

(2011) P. Asp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells

(2011) Lovorka Stojic et al.   Epigenetics & Chromatin

Pericytes resident in postnatal skeletal muscle differentiate into muscle fibres and generate satellite cells

(2011) A. Dellavalle et al.   Nature Communications

A New Isoform of the Histone Demethylase JMJD2A/KDM4A Is Required for Skeletal Muscle Differentiation

(2011) Laure Verrier et al.   PLoS Genetics

Regulatory interactions between muscle and the immune system during muscle regeneration

(2010) James G. Tidball et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

(2010) Alessandra Sacco et al.   CELL

MicroRNAs Involved in Molecular Circuitries Relevant for the Duchenne Muscular Dystrophy Pathogenesis Are Controlled by the Dystrophin/nNOS Pathway

(2010) Davide Cacchiarelli et al.   Cell Metabolism

TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

(2010) Daniela Palacios et al.   Cell Stem Cell

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

(2010) Shayesta Seenundun et al.   EMBO JOURNAL

Preferential association of irreversibly silenced E2F-target genes with pericentromeric heterochromatin in differentiated muscle cells

(2010) Valentina Guasconi et al.   Epigenetics

Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P3 Axis

(2010) Francesca Cencetti et al.   MOLECULAR BIOLOGY OF THE CELL

Identification and characterization of a non-satellite cell muscle resident progenitor during postnatal development

(2010) Kathryn J. Mitchell et al.   NATURE CELL BIOLOGY

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment

(2010) C. Colussi et al.   Proteomics Clinical Applications

Histone Deacetylase Inhibition Elicits an Evolutionarily Conserved Self-Renewal Program in Embryonic Stem Cells

(2009) Carol B. Ware et al.   Cell Stem Cell

Molecular aging and rejuvenation of human muscle stem cells

(2009) Morgan E. Carlson et al.   EMBO Molecular Medicine

Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy

(2009) Claudia Colussi et al.   FASEB JOURNAL

p38-γ–dependent gene silencing restricts entry into the myogenic differentiation program

(2009) Mark A. Gillespie et al.   JOURNAL OF CELL BIOLOGY

Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells

(2009) Aster H. Juan et al.   MOLECULAR CELL

Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease

(2009) Louise R. Rodino-Klapac et al.   MUSCLE & NERVE

Chromatin: the interface between extrinsic cues and the epigenetic regulation of muscle regeneration

(2009) Valentina Guasconi et al.   TRENDS IN CELL BIOLOGY

Regenerative pharmacology in the treatment of genetic diseases: The paradigm of muscular dystrophy

(2008) Chiara Mozzetta et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

S-nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons

(2008) Alexi Nott et al.   NATURE

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

(2008) Jiancong Liang et al.   NATURE CELL BIOLOGY

The immune system and the repair of skeletal muscle

(2008) S BRUNELLI et al.   PHARMACOLOGICAL RESEARCH

HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

(2008) C. Colussi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis

(2008) Efthimia Karantzal et al.   GENOME BIOLOGY