Sirt3 Ameliorates Oxidative Stress and Mitochondrial Dysfunction After Intracerebral Hemorrhage in Diabetic Rats

PERK Pathway Activation Promotes Intracerebral Hemorrhage Induced Secondary Brain Injury by Inducing Neuronal Apoptosis Both in Vivo and in Vitro

(2018) Chengjie Meng et al.   Frontiers in Neuroscience

Mdivi-1 ameliorates early brain injury after subarachnoid hemorrhage via the suppression of inflammation-related blood–brain barrier disruption and endoplasmic reticulum stress-based apoptosis

(2017) Lin-feng Fan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial biogenesis in neurodegeneration

(2017) P. Andy Li et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Melatonin ameliorates myocardial ischemia reperfusion injury through SIRT3-dependent regulation of oxidative stress and apoptosis

(2017) Mengen Zhai et al.   JOURNAL OF PINEAL RESEARCH

Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway

(2017) Ming‐liang Chen et al.   Journal of the American Heart Association

Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling

(2017) Liming Yu et al.   Scientific Reports

Deacetylation of MnSOD by PARP-regulated SIRT3 protects retinal capillary endothelial cells from hyperglycemia-induced damage

(2016) Jian Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NLRP3 inflammasome: a promising target in ischemic stroke

(2016) Li Gao et al.   INFLAMMATION RESEARCH

Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy

(2016) Xiaochun Duan et al.   Oxidative Medicine and Cellular Longevity

Regulation of mitochondrial biogenesis through TFAM–mitochondrial DNA interactions

(2015) Anna Picca et al.   MITOCHONDRION

Mechanisms of Neuronal Protection against Excitotoxicity, Endoplasmic Reticulum Stress, and Mitochondrial Dysfunction in Stroke and Neurodegenerative Diseases

(2015) Howard Prentice et al.   Oxidative Medicine and Cellular Longevity

Perihematomal Edema and Functional Outcomes in Intracerebral Hemorrhage

(2015) Santosh B. Murthy et al.   STROKE

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

(2015) Vinodkumar B. Pillai et al.   Nature Communications

Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice

(2014) Kunjbihari Sulakhiya et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Opposing Effects of Glucose on Stroke and Reperfusion Injury

(2014) Nathaniel M. Robbins et al.   STROKE

NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage

(2013) Qingyi Ma et al.   ANNALS OF NEUROLOGY

Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation

(2013) Yu Zhou et al.   PROGRESS IN NEUROBIOLOGY

Hyperglycemia Exacerbates Intracerebral Hemorrhage via the Downregulation of Aquaporin-4

(2013) Cheng-Di Chiu et al.   STROKE

Neuro-Modulating Effects of Honokiol: A Review

(2013) Anna Woodbury et al.   Frontiers in Neurology

SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging

(2012) Albert Giralt et al.   BIOCHEMICAL JOURNAL

SIRT3 regulation of mitochondrial oxidative stress

(2012) Alexandra S. Bause et al.   EXPERIMENTAL GERONTOLOGY

Honokiol suppresses the development of post-ischemic glucose intolerance and neuronal damage in mice

(2012) Shinichi Harada et al.   Journal of Natural Medicines

Serum biomarkers of spontaneous intracerebral hemorrhage induced secondary brain injury

(2012) Andrew S. Brunswick et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein

(2011) Jia Liu et al.   NATURE MEDICINE

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

Sirt3 protects in vitro–fertilized mouse preimplantation embryos against oxidative stress–induced p53-mediated developmental arrest

(2010) Yumiko Kawamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis

(2010) Charlotte JJ van Asch et al.   LANCET NEUROLOGY

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

Intracerebral haemorrhage

(2009) Adnan I Qureshi et al.   LANCET

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA