Caffeine acts through neuronal adenosine A2Areceptors to prevent mood and memory dysfunction triggered by chronic stress

Astrocytic Adenosine A2A Receptors Control the Amyloid-β Peptide-Induced Decrease of Glutamate Uptake

(2018) Marco Matos et al.   JOURNAL OF ALZHEIMERS DISEASE

Chronic Caffeine Consumption Prevents Memory Disturbance in Different Animal Models of Memory Decline

(2017) Rodrigo A. Cunha et al.   JOURNAL OF ALZHEIMERS DISEASE

Antidepressant activity of the adenosine A2A receptor antagonist, istradefylline (KW-6002) on learned helplessness in rats

(2014) Koji Yamada et al.   PSYCHOPHARMACOLOGY

From Pathophysiology to Novel Antidepressant Drugs: Glial Contributions to the Pathology and Treatment of Mood Disorders

(2013) Gerard Sanacora et al.   BIOLOGICAL PSYCHIATRY

Spatial memory impairments in a prediabetic rat model

(2013) E. Soares et al.   NEUROSCIENCE

Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

(2013) C. G. Silva et al.   Science Translational Medicine

Coffee, caffeine, and risk of completed suicide: Results from three prospective cohorts of American adults

(2013) Michel Lucas et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Caffeine prevents cognitive impairment induced by chronic psychosocial stress and/or high fat–high carbohydrate diet

(2012) K.H. Alzoubi et al.   BEHAVIOURAL BRAIN RESEARCH

Effect of long-term caffeine administration on depressive-like behavior in rats exposed to chronic unpredictable stress

(2012) Daniela M. Pechlivanova et al.   BEHAVIOURAL PHARMACOLOGY

Adenosine A2A receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation

(2012) V L Batalha et al.   MOLECULAR PSYCHIATRY

Neurobiology of chronic mild stress: Parallels to major depression

(2012) Matthew N. Hill et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Caffeine Consumption Prevents Diabetes-Induced Memory Impairment and Synaptotoxicity in the Hippocampus of NONcZNO10/LTJ Mice

(2012) João M. N. Duarte et al.   PLoS One

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Coffee, Caffeine, and Risk of Depression Among Women

(2011) Michel Lucas   ARCHIVES OF INTERNAL MEDICINE

Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing

(2011) Ana R. Costenla et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction

(2011) Nelson Rebola et al.   JOURNAL OF NEUROCHEMISTRY

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

(2011) Maurizio Popoli et al.   NATURE REVIEWS NEUROSCIENCE

Caffeine and an adenosine A2Areceptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life

(2009) Giana P. Cognato et al.   JOURNAL OF NEUROCHEMISTRY

Adenosine A2A Receptor Blockade Prevents Synaptotoxicity and Memory Dysfunction Caused by  -Amyloid Peptides via p38 Mitogen-Activated Protein Kinase Pathway

(2009) P. M. Canas et al.   JOURNAL OF NEUROSCIENCE

Adenosine A2Areceptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms

(2008) Liqun Yu et al.   ANNALS OF NEUROLOGY

Enhancing brain adenosine signaling with the nucleoside transport blocker NBTI (S-(4-nitrobenzyl)-6-theoinosine) mimics the effects of inescapable shock on later shuttle-escape performance in rats.

(2008) Thomas R. Minor et al.   BEHAVIORAL NEUROSCIENCE

The A2A-adenosine receptor: a GPCR with unique features?

(2008) J Zezula et al.   BRITISH JOURNAL OF PHARMACOLOGY

Is there a major role for adenosine a2a receptors in anxiety?

(2008) Merce Correa   Frontiers in Bioscience-Landmark

Caffeine, cognitive failures and health in a non-working community sample

(2008) Andrew P Smith   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

A Critical Role of the Adenosine A2A Receptor in Extrastriatal Neurons in Modulating Psychomotor Activity as Revealed by Opposite Phenotypes of Striatum and Forebrain A2A Receptor Knock-Outs

(2008) H.-Y. Shen et al.   JOURNAL OF NEUROSCIENCE