Abl and Arg mediate cysteine cathepsin secretion to facilitate melanoma invasion and metastasis

Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma

(2017) A Jain et al.   ONCOGENE

Phenotypic tumour cell plasticity as a resistance mechanism and therapeutic target in melanoma

(2016) Alexander Roesch et al.   EUROPEAN JOURNAL OF CANCER

SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells

(2016) Shira Ashkenazi et al.   Oncotarget

Cathepsin L targeting in cancer treatment

(2015) Dhivya R. Sudhan et al.   PHARMACOLOGY & THERAPEUTICS

Sp1 transcription factor: A long-standing target in cancer chemotherapy

(2015) Carolina Vizcaíno et al.   PHARMACOLOGY & THERAPEUTICS

The role of the transcription factor Ets1 in carcinoma

(2015) Jürgen Dittmer   SEMINARS IN CANCER BIOLOGY

RAB7 Controls Melanoma Progression by Exploiting a Lineage-Specific Wiring of the Endolysosomal Pathway

(2014) Direna Alonso-Curbelo et al.   CANCER CELL

The Tetraspanin CD81 Protein Increases Melanoma Cell Motility by Up-regulating Metalloproteinase MT1-MMP Expression through the Pro-oncogenic Akt-dependent Sp1 Activation Signaling Pathways

(2014) In-Kee Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PAX3 and ETS1 synergistically activate MET expression in melanoma cells

(2014) J D Kubic et al.   ONCOGENE

Cathepsin B: Multiple roles in cancer

(2014) Neha Aggarwal et al.   Proteomics Clinical Applications

The role of the cytoskeleton and molecular motors in endosomal dynamics

(2014) Elizabeth Granger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Defying c-Abl signaling circuits through small allosteric compounds

(2014) Stefania Gonfloni   Frontiers in Genetics

A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma

(2013) Julie Caramel et al.   CANCER CELL

Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization

(2013) Donna M. Small et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of novel human cathepsin S inhibitors on cell migration in human cancer cells

(2013) Ju-Ying Tsai et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer

(2013) L S Fiore et al.   ONCOGENE

Imatinib Reverses Doxorubicin Resistance by Affecting Activation of STAT3-Dependent NF-κB and HSP27/p38/AKT Pathways and by Inhibiting ABCB1

(2013) Jonathan T. Sims et al.   PLoS One

Cysteine cathepsins: From structure, function and regulation to new frontiers

(2011) Vito Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

ETS-1/RhoC signaling regulates the transcription factor c-Jun in melanoma

(2011) Barbara Spangler et al.   INTERNATIONAL JOURNAL OF CANCER

IL8 and Cathepsin B as Melanoma Serum Biomarkers

(2011) Hongtao Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrin-linked kinase regulates melanoma angiogenesis by activating NF-κB/interleukin-6 signaling pathway

(2011) A A Wani et al.   ONCOGENE

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways and drive metastatic progression

(2011) S S Ganguly et al.   ONCOGENE

Constitutive activation of the ETS-1-miR-222 circuitry in metastatic melanoma

(2011) Gianfranco Mattia et al.   Pigment Cell & Melanoma Research

c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3

(2010) X Li et al.   CELL DEATH AND DIFFERENTIATION

Conditional ablation of Ikkb inhibits melanoma tumor development in mice

(2010) Jinming Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8

(2010) Iwona Sachrajda et al.   MOLECULAR GENETICS AND GENOMICS

Nuclear factor-κB expression is predictive of overall survival in patients with cutaneous melanoma

(2010) DANIELA MURTAS et al.   Oncology Letters

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

(2008) Adam I Riker et al.   BMC Medical Genomics

SHP-2 is a novel target of Abl kinases during cell proliferation

(2008) S. Mitra et al.   JOURNAL OF CELL SCIENCE