Imatinib Reverses Doxorubicin Resistance by Affecting Activation of STAT3-Dependent NF-κB and HSP27/p38/AKT Pathways and by Inhibiting ABCB1

Enhanced Resistance to Tamoxifen by the c-ABL Proto-oncogene in Breast Cancer

(2015) Huajun Zhao et al.   NEOPLASIA

Doxorubicin-induced activation of NF-κB in melanoma cells is abrogated by inhibition of IKKβ, but not by a novel IKKα inhibitor

(2012) Nadin Pletz et al.   EXPERIMENTAL DERMATOLOGY

Mechanisms and management of doxorubicin cardiotoxicity

(2011) Y. Shi et al.   HERZ

Forced Expression of Heat Shock Protein 27 (Hsp27) Reverses P-Glycoprotein (ABCB1)-mediated Drug Efflux andMDR1Gene Expression in Adriamycin-resistant Human Breast Cancer Cells

(2011) Ragu Kanagasabai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Rit GTPase-p38 Mitogen-Activated Protein Kinase Survival Pathway Confers Resistance to Cellular Stress

(2011) G.-X. Shi et al.   MOLECULAR AND CELLULAR BIOLOGY

c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways and drive metastatic progression

(2011) S S Ganguly et al.   ONCOGENE

Other Options in the Treatment of Advanced Breast Cancer

(2011) Melody A. Cobleigh   SEMINARS IN ONCOLOGY

Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis

(2010) N Walsh et al.   BRITISH JOURNAL OF CANCER

The PI3K Pathway As Drug Target in Human Cancer

(2010) Kevin D. Courtney et al.   JOURNAL OF CLINICAL ONCOLOGY

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

(2010) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

NF-κB addiction and its role in cancer: ‘one size does not fit all’

(2010) M M Chaturvedi et al.   ONCOGENE

Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer

(2009) Bharat B. Aggarwal et al.   Annals of the New York Academy of Sciences

STI571 sensitizes breast cancer cells to 5-fluorouracil, cisplatin and camptothecin in a cell type-specific manner

(2009) Jonathan T. Sims et al.   BIOCHEMICAL PHARMACOLOGY

Nilotinib (AMN107, Tasigna ® ) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters

(2009) Amit K. Tiwari et al.   BIOCHEMICAL PHARMACOLOGY

Dissecting the role of mTOR: Lessons from mTOR inhibitors

(2009) Ryan J.O. Dowling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines

(2009) Jonathan T. Sims et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells

(2009) Anne-Marie Bleau et al.   Cell Stem Cell

Reciprocal regulation of Abl and receptor tyrosine kinases

(2009) Divyamani Srinivasan et al.   CELLULAR SIGNALLING

Treatment for metastatic malignant melanoma: Old drugs and new strategies

(2009) Roger Mouawad et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Retracted:Inhibition of constitutive activity of nuclear transcription factor kappaB sensitizes doxorubicin-resistant cells to apoptosis

(2009) Charitha Gangadharan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pharmacogenetics of Membrane Transporters: An Update on Current Approaches

(2009) Tristan M. Sissung et al.   MOLECULAR BIOTECHNOLOGY

DNA fingerprinting of the NCI-60 cell line panel

(2009) P. L. Lorenzi et al.   MOLECULAR CANCER THERAPEUTICS

The prognostic importance of triple negative breast carcinoma

(2008) Hakan Mersin et al.   BREAST

Nilotinib

(2008) M. W. Deininger   CLINICAL CANCER RESEARCH

SHP-2 is a novel target of Abl kinases during cell proliferation

(2008) S. Mitra et al.   JOURNAL OF CELL SCIENCE

The RelA/p65 subunit of NF-κB specifically regulates cyclin D1 protein stability: Implications for cell cycle withdrawal and skeletal myogenesis

(2008) Jason M. Dahlman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Forkhead Transcription Factor FOXO3a Increases Phosphoinositide-3 Kinase/Akt Activity in Drug-Resistant Leukemic Cells through Induction of PIK3CA Expression

(2008) R. C.-Y. Hui et al.   MOLECULAR AND CELLULAR BIOLOGY