The double-edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

(2017) Guangyan Xiong et al.   eLife

Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia

(2017) Thomas Scott Bowen et al.   Journal of Cachexia Sarcopenia and Muscle

Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction

(2017) Yuki Enoki et al.   Journal of Cachexia Sarcopenia and Muscle

Urolithin B, a newly identified regulator of skeletal muscle mass

(2017) Julie Rodriguez et al.   Journal of Cachexia Sarcopenia and Muscle

Is cardiac wasting accompanied by skeletal muscle loss in breast cancer patients receiving anticancer treatment?

(2017) Junichi Ishida et al.   Journal of Cachexia Sarcopenia and Muscle

Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue

(2016) Amiya Kumar Ghosh et al.   Aging-US

Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal

(2016) Victoria Zismanov et al.   Cell Stem Cell

The ageing neuromuscular system and sarcopenia: a mitochondrial perspective

(2016) Karolina A. Rygiel et al.   JOURNAL OF PHYSIOLOGY-LONDON

Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

(2016) Yuki Enoki et al.   Scientific Reports

Indoxyl sulfate induces oxidative stress and hypertrophy in cardiomyocytes by inhibiting the AMPK/UCP2 signaling pathway

(2015) Ke Yang et al.   TOXICOLOGY LETTERS

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015

(2015) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Proteostasis in endoplasmic reticulum—new mechanisms in kidney disease

(2014) Reiko Inagi et al.   Nature Reviews Nephrology

Chronic kidney disease and premature ageing

(2014) Jeroen P. Kooman et al.   Nature Reviews Nephrology

Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells

(2014) Y Teng et al.   Cell Death & Disease

Chronic Kidney Disease: A Clinical Model of Premature Aging

(2013) Peter Stenvinkel et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

CREB, NF-κB, and NADPH oxidase coordinately upregulate indoxyl sulfate-induced angiotensinogen expression in proximal tubular cells

(2013) Hidehisa Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Modulation of the Akt Pathway Reveals a Novel Link with PERK/eIF2α, which Is Relevant during Hypoxia

(2013) Matías Blaustein et al.   PLoS One

Stat3 Contributes to Indoxyl Sulfate-Induced Inflammatory and Fibrotic Gene Expression and Cellular Senescence

(2012) Hidehisa Shimizu et al.   AMERICAN JOURNAL OF NEPHROLOGY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ApoE ε4 is associated with eIF2α phosphorylation and impaired learning in young mice

(2012) Yifat Segev et al.   NEUROBIOLOGY OF AGING

PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis

(2011) P Briata et al.   CELL DEATH AND DIFFERENTIATION

Menopause and sarcopenia: A potential role for sex hormones

(2011) Virginie Messier et al.   MATURITAS

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction

(2011) Yingjiang Zhou et al.   NATURE MEDICINE

Akt Determines Cell Fate Through Inhibition of the PERK-eIF2  Phosphorylation Pathway

(2011) Z. Mounir et al.   Science Signaling

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Myostatin knockout mice increase oxidative muscle phenotype as an adaptive response to exercise

(2010) Antonios Matsakas et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–binding protein-1 to modulate the unfolded protein response

(2010) Jonathon N Winnay et al.   NATURE MEDICINE

The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation

(2010) Sang Won Park et al.   NATURE MEDICINE

Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering

(2010) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER and aging—Protein folding and the ER stress response

(2009) Nirinjini Naidoo   AGEING RESEARCH REVIEWS

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling

(2009) Micah J. Drummond et al.   JOURNAL OF APPLIED PHYSIOLOGY

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY