Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction

L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE−/− transgenic mice expressing CETP

(2016) Heidi L. Collins et al.   ATHEROSCLEROSIS

A novel DPP-4 inhibitor teneligliptin scavenges hydroxyl radicals: In vitro study evaluated by electron spin resonance spectroscopy and in vivo study using DPP-4 deficient rats

(2016) Shinichiro Kimura et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease

(2016) Emiko Sato et al.   Scientific Reports

Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

(2016) Yuki Enoki et al.   Scientific Reports

l -Carnitine enhances exercise endurance capacity by promoting muscle oxidative metabolism in mice

(2015) Jun Ho Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Light-Intensity Physical Activities and Mortality in the United States General Population and CKD Subpopulation

(2015) S. Beddhu et al.   Clinical Journal of the American Society of Nephrology

Oral L-Carnitine Supplementation Increases Trimethylamine-N-oxide but Reduces Markers of Vascular Injury in Hemodialysis Patients

(2015) Kei Fukami et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

AST-120 ameliorates lowered exercise capacity and mitochondrial biogenesis in the skeletal muscle from mice with chronic kidney disease via reducing oxidative stress

(2015) Mikito Nishikawa et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Potential Therapeutic Role of L-Carnitine in Skeletal Muscle Oxidative Stress and Atrophy Conditions

(2015) Anna Montesano et al.   Oxidative Medicine and Cellular Longevity

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015

(2015) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

The Influence of Dietary Protein Intake on Mammalian Tryptophan and Phenolic Metabolites

(2015) Ruben Poesen et al.   PLoS One

The Uremic Toxicity of Indoxyl Sulfate and p-Cresyl Sulfate: A Systematic Review

(2014) R. Vanholder et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mechanisms of muscle wasting in chronic kidney disease

(2014) Xiaonan H. Wang et al.   Nature Reviews Nephrology

L-Carnitine Prevents Progression of Non-Alcoholic Steatohepatitis in a Mouse Model with Upregulation of Mitochondrial Pathway

(2014) Hisashi Ishikawa et al.   PLoS One

Hindbrain GLP-1 receptor-mediated suppression of food intake requires a PI3K-dependent decrease in phosphorylation of membrane-bound Akt

(2013) Laura E. Rupprecht et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The novel dipeptidyl peptidase-4 inhibitor teneligliptin prevents high-fat diet-induced obesity accompanied with increased energy expenditure in mice

(2013) Sayaka Fukuda-Tsuru et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

p -Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase

(2013) Hiroshi Watanabe et al.   KIDNEY INTERNATIONAL

Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase

(2013) Masanori Tamaki et al.   KIDNEY INTERNATIONAL

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats

(2013) Janine Keller et al.   Nutrition & Metabolism

Carnitine supplementation to obese Zucker rats prevents obesity-induced type II to type I muscle fiber transition and favors an oxidative phenotype of skeletal muscle

(2013) Aline Couturier et al.   Nutrition & Metabolism

Effects of Hyperbaric Oxygen on Metabolic Capacity of the Skeletal Muscle in Type 2 Diabetic Rats with Obesity

(2012) Naoto Fujita et al.   TheScientificWorldJOURNAL

PGC-1α mRNA Level and Oxidative Capacity of the Plantaris Muscle in Rats with Metabolic Syndrome, Hypertension, and Type 2 Diabetes

(2011) Fumiko Nagatomo et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Modulation of reactive oxygen species in skeletal muscle by myostatin is mediated through NF-κB

(2011) Sandhya Sriram et al.   AGING CELL

Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease

(2011) Liping Zhang et al.   FASEB JOURNAL

Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy

(2010) Jeffrey J. Brault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Muscle atrophy, inflammation and clinical outcome in incident and prevalent dialysis patients

(2008) Juan Jesús Carrero et al.   CLINICAL NUTRITION

PGC-1 coactivators and skeletal muscle adaptations in health and disease

(2008) Zolt Arany   CURRENT OPINION IN GENETICS & DEVELOPMENT