Human Endogenous Retroviruses and Their Putative Role in the Development of Autoimmune Disorders Such as Multiple Sclerosis

Potential molecular mimicry between the human endogenous retrovirus W family envelope proteins and myelin proteins in multiple sclerosis

(2017) Ranjan Ramasamy et al.   IMMUNOLOGY LETTERS

Retroviral envelope proteins: Involvement in neuropathogenesis

(2017) Dorte Tranberg Hansen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Epigenetic Control of Human Endogenous Retrovirus Expression: Focus on Regulation of Long-Terminal Repeats (LTRs)

(2017) Tara Hurst et al.   Viruses-Basel

The association between human endogenous retroviruses and multiple sclerosis: A systematic review and meta-analysis

(2017) Elena Morandi et al.   PLoS One

Antigenic and immunosuppressive properties of a trimeric recombinant transmembrane envelope protein gp41 of HIV-1

(2017) Michael Mühle et al.   PLoS One

AB0082 Anti-Inflammatory Activity of A Human Endogenous Retroviral Genetic Element in Experimental Arthritis

(2016) M.J. Laska et al.   ANNALS OF THE RHEUMATIC DISEASES

Two endogenous retroviral loci appear to contribute to Multiple Sclerosis

(2016) Bjørn A. Nexø et al.   BMC Neurology

How retrotransposons shape genome regulation

(2016) Paolo Mita et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

(2016) Tara Hurst et al.   Retrovirology

Classification and characterization of human endogenous retroviruses; mosaic forms are common

(2016) Laura Vargiu et al.   Retrovirology

Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis

(2016) Jack van Horssen et al.   Multiple Sclerosis and Related Disorders

Are human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral loci

(2015) Bjørn A. Nexø et al.   IMMUNOLOGIC RESEARCH

DNA methylation modulates HERV-E expression in CD4+ T cells from systemic lupus erythematosus patients

(2015) Zhouwei Wu et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Activation of the innate immune response by endogenous retroviruses

(2015) T. P. Hurst et al.   JOURNAL OF GENERAL VIROLOGY

Treatment Against Human Endogenous Retrovirus: A Possible Personalized Medicine Approach for Multiple Sclerosis

(2015) François Curtin et al.   Molecular Diagnosis & Therapy

Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells

(2015) Edward J. Grow et al.   NATURE

Human endogenous retrovirus-K contributes to motor neuron disease

(2015) Wenxue Li et al.   Science Translational Medicine

The transmembrane proteins contribute to immunodeficiencies induced by HIV-1 and other retroviruses

(2014) Joachim Denner   AIDS

Induction of Immunoregulatory CD271+ Cells by Metastatic Tumor Cells That Express Human Endogenous Retrovirus H

(2014) C. Kudo-Saito et al.   CANCER RESEARCH

The Retrovirus/Superantigen Hypothesis of Multiple Sclerosis

(2014) Alexander Emmer et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Rheumatoid Arthritis is Associated with IgG Antibodies to Human Endogenous Retrovirus Gag Matrix: A Potential Pathogenic Mechanism of Disease?

(2014) P. N. Nelson et al.   JOURNAL OF RHEUMATOLOGY

Unfixed Endogenous Retroviral Insertions in the Human Population

(2014) E. Marchi et al.   JOURNAL OF VIROLOGY

Human Endogenous Retrovirus HERV-Fc1 Association with Multiple Sclerosis Susceptibility: A Meta-Analysis

(2014) Belén de la Hera et al.   PLoS One

Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation

(2013) David Kremer et al.   ANNALS OF NEUROLOGY

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE

(2013) Tiffany N Caza et al.   ANNALS OF THE RHEUMATIC DISEASES

Retroviruses and amyotrophic lateral sclerosis

(2013) Tariq Alfahad et al.   ANTIVIRAL RESEARCH

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis

(2013) George R. Young et al.   BIOESSAYS

Human endogenous retroviruses and cancer prevention: evidence and prospects

(2013) Luca Cegolon et al.   BMC CANCER

Immunosuppressive domains of retroviruses: Cell mechanisms of the effect on the human immune system

(2013) V. M. Blinov et al.   MOLECULAR BIOLOGY

Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1

(2013) Joachim Denner et al.   PLoS One

Role of the Human Endogenous Retrovirus HERV-K18 in Autoimmune Disease Susceptibility: Study in the Spanish Population and Meta-Analysis

(2013) Belén de la Hera et al.   PLoS One

The Transmembrane Protein of the Human Endogenous Retrovirus - K (HERV-K) Modulates Cytokine Release and Gene Expression

(2013) Vladimir A. Morozov et al.   PLoS One

Human Endogenous Retrovirus Protein Activates Innate Immunity and Promotes Experimental Allergic Encephalomyelitis in Mice

(2013) Hervé Perron et al.   PLoS One

Expression of human endogenous retrovirus HERV-K18 is associated with clinical severity in osteoarthritis patients

(2013) M Garcia-Montojo et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Expression of HERV-Fc1, a Human Endogenous Retrovirus, Is Increased in Patients with Active Multiple Sclerosis

(2012) M. J. Laska et al.   JOURNAL OF VIROLOGY

Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease

(2012) Hervé Perron et al.   Multiple Sclerosis Journal

Studies of endogenous retroviruses reveal a continuing evolutionary saga

(2012) Jonathan P. Stoye   NATURE REVIEWS MICROBIOLOGY

The endogenous retroviral envelope protein syncytin-1 inhibits LPS/PHA-stimulated cytokine responses in human blood and is sorted into placental exosomes

(2012) J.M. Tolosa et al.   PLACENTA

From ancestral infectious retroviruses to bona fide cellular genes: Role of the captured syncytins in placentation

(2012) A. Dupressoir et al.   PLACENTA

No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients

(2012) Kari K Nissen et al.   Virology Journal

Genetic Association of Multiple Sclerosis with the Marker rs391745 near the Endogenous Retroviral Locus HERV-Fc1: Analysis of Disease Subtypes

(2011) Bettina Hansen et al.   PLoS One

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

(2011) Mikayla R. Thompson et al.   Viruses-Basel

Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis

(2010) Renée Douville et al.   ANNALS OF NEUROLOGY

A role for human endogenous retrovirus-K (HML-2) in rheumatoid arthritis: investigating mechanisms of pathogenesis

(2010) G. Freimanis et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Implication of Human Endogenous Retroviruses in the Development of Autoimmune Diseases

(2010) Eva Balada et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

HERVs in Neuropathogenesis

(2010) Tove Christensen   Journal of Neuroimmune Pharmacology

Preactive lesions in multiple sclerosis

(2009) Paul van der Valk et al.   CURRENT OPINION IN NEUROLOGY

B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity

(2009) Tomasz Brudek et al.   Retrovirology

Molecular mechanisms mediated by human endogenous retroviruses (HERVs) in autoimmunity

(2009) Eva Balada et al.   REVIEWS IN MEDICAL VIROLOGY

Increase in Human Endogenous Retrovirus HERV-K (HML-2) Viral Load in Active Rheumatoid Arthritis

(2009) F. Reynier et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

ENDOGENOUS RETROVIRUSES IN SYSTEMIC RESPONSE TO STRESS SIGNALS

(2009) Kiho Cho et al.   SHOCK

Haplotypes of the HRES-1 endogenous retrovirus are associated with development and disease manifestations of systemic lupus erythematosus

(2008) Rudolf Pullmann et al.   ARTHRITIS AND RHEUMATISM

The role of infections in autoimmune disease

(2008) A. M. Ercolini et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human RNA "Rumor" Viruses: the Search for Novel Human Retroviruses in Chronic Disease

(2008) C. Voisset et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Human endogenous retrovirus-K18 Env as a risk factor in multiple sclerosis

(2008) AK Tai et al.   Multiple Sclerosis Journal