Epigenetic Control of Human Endogenous Retrovirus Expression: Focus on Regulation of Long-Terminal Repeats (LTRs)

KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks

(2017) Michaël Imbeault et al.   NATURE

Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment

(2017) Pedro M. Aponte et al.   Stem Cells International

Expression and function of endogenous retroviruses in the placenta

(2016) Joachim Denner   APMIS

Dynamic and selective HERV RNA expression in neuroblastoma cells subjected to variation in oxygen tension and demethylation

(2016) Lijuan Hu et al.   APMIS

Epigenetic silencing of tumor suppressor genes: Paradigms, puzzles, and potential

(2016) Anna Kazanets et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Maintaining memory of silencing at imprinted differentially methylated regions

(2016) Hsiao P. J. Voon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues

(2016) Gabriela Ecco et al.   DEVELOPMENTAL CELL

Regulating retrotransposon activity through the use of alternative transcription start sites

(2016) Jenna Persson et al.   EMBO REPORTS

NF-κB and IRF1 Induce Endogenous Retrovirus K Expression via Interferon-Stimulated Response Elements in Its 5′ Long Terminal Repeat

(2016) Mamneet Manghera et al.   JOURNAL OF VIROLOGY

Long Terminal Repeats: From Parasitic Elements to Building Blocks of the Transcriptional Regulatory Repertoire

(2016) Peter J. Thompson et al.   MOLECULAR CELL

The molecular hallmarks of epigenetic control

(2016) C. David Allis et al.   NATURE REVIEWS GENETICS

Expression patterns of ERVWE1/Syncytin-1 and other placentally expressed human endogenous retroviruses along the malignant transformation process of hydatidiform moles

(2016) Pierre-Adrien Bolze et al.   PLACENTA

Discovery of unfixed endogenous retrovirus insertions in diverse human populations

(2016) Julia Halo Wildschutte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

(2016) Tara Hurst et al.   Retrovirology

TRIM28 Is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming

(2016) Denise Catherine Miles et al.   STEM CELLS

Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis

(2016) Rebeca Campos-Sánchez et al.   PLoS Computational Biology

HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases

(2016) Elizabeth E. Hull et al.   Biomed Research International

Endogenous retroviral promoter exaptation in human cancer

(2016) Artem Babaian et al.   Mobile DNA

Human endogenous retroviruses and cancer

(2016) Gonzalez-Cao María et al.   Cancer Biology & Medicine

Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response

(2016) Yoshimasa Saito et al.   Scientific Reports

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

(2015) Katherine B. Chiappinelli et al.   CELL

Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death

(2015) U Beyer et al.   CELL DEATH AND DIFFERENTIATION

Controlling Endogenous Retroviruses and Their Chimeric Transcripts During Natural Reprogramming in the Oocyte

(2015) Ai Khim Lim et al.   JOURNAL OF INFECTIOUS DISEASES

Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells

(2015) Edward J. Grow et al.   NATURE

The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes

(2015) Patrick L. Collins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide amplification of proviral sequences reveals new polymorphic HERV-K(HML-2) proviruses in humans and chimpanzees that are absent from genome assemblies

(2015) Catriona M Macfarlane et al.   Retrovirology

Differential Expression of HERV-K (HML-2) Proviruses in Cells and Virions of the Teratocarcinoma Cell Line Tera-1

(2015) Neeru Bhardwaj et al.   Viruses-Basel

TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells

(2015) Liana Fasching et al.   Cell Reports

HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues

(2015) Katja Schmitt et al.   Mobile DNA

Chimeric antigen receptor T cells targeting HERV-K inhibit breast cancer and its metastasis through downregulation of Ras

(2015) Fuling Zhou et al.   OncoImmunology

Diverse Epigenetic Mechanisms of Human Disease

(2014) Emily Brookes et al.   Annual Review of Genetics

Transcriptional landscape of repetitive elements in normal and cancer human cells

(2014) Steven W Criscione et al.   BMC GENOMICS

Cytotoxicity of Human Endogenous Retrovirus K-Specific T Cells toward Autologous Ovarian Cancer Cells

(2014) K. Rycaj et al.   CLINICAL CANCER RESEARCH

Prenatal exposure to mixtures of xenoestrogens and repetitive element DNA methylation changes in human placenta

(2014) Nadia Vilahur et al.   ENVIRONMENT INTERNATIONAL

Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?

(2014) Ronan F. Downey et al.   INTERNATIONAL JOURNAL OF CANCER

Unfixed Endogenous Retroviral Insertions in the Human Population

(2014) E. Marchi et al.   JOURNAL OF VIROLOGY

Transcriptional Derepression of the ERVWE1 Locus following Influenza A Virus Infection

(2014) F. Li et al.   JOURNAL OF VIROLOGY

The enemy within: endogenous retroelements and autoimmune disease

(2014) Hannah E Volkman et al.   NATURE IMMUNOLOGY

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity

(2014) Xinyi Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Larger Mammalian Body Size Leads to Lower Retroviral Activity

(2014) Aris Katzourakis et al.   PLoS Pathogens

The diversity of zinc-finger genes on human chromosome 19 provides an evolutionary mechanism for defense against inherited endogenous retroviruses

(2013) S Lukic et al.   CELL DEATH AND DIFFERENTIATION

Epigenetic and non-epigenetic regulation of syncytin-1 expression in human placenta and cancer tissues

(2013) Qiang Huang et al.   CELLULAR SIGNALLING

Human endogenous retrovirus type K antibodies and mRNA as serum biomarkers of early-stage breast cancer

(2013) Feng Wang-Johanning et al.   INTERNATIONAL JOURNAL OF CANCER

The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

(2013) T Chen et al.   LEUKEMIA

Human endogenous retrovirus K (HERV-K)recmRNA is expressed in primary melanoma but not in benign naevi or normal skin

(2013) Sarita Singh et al.   Pigment Cell & Melanoma Research

Human-Specific HERV-K Insertion Causes Genomic Variations in the Human Genome

(2013) Wonseok Shin et al.   PLoS One

Endogenous retrovirus-K promoter: a landing strip for inflammatory transcription factors?

(2013) Mamneet Manghera et al.   Retrovirology

Comparison of HDAC inhibitors in clinical development

(2013) Thomas Aagaard Rasmussen et al.   Human Vaccines & Immunotherapeutics

VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer

(2013) Georges St Laurent et al.   GENOME BIOLOGY

Expression of HERV-Fc1, a Human Endogenous Retrovirus, Is Increased in Patients with Active Multiple Sclerosis

(2012) M. J. Laska et al.   JOURNAL OF VIROLOGY

Expression of Human Endogenous Retrovirus Type K (HML-2) Is Activated by the Tat Protein of HIV-1

(2012) M. J. Gonzalez-Hernandez et al.   JOURNAL OF VIROLOGY

Microarray-Based Sketches of the HERV Transcriptome Landscape

(2012) Philippe Pérot et al.   PLoS One

HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency

(2012) Federico A Santoni et al.   Retrovirology

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Coevolution of retroelements and tandem zinc finger genes

(2011) J. H. Thomas et al.   GENOME RESEARCH

Human endogenous retrovirus K (HERV-K) is expressed in villous and extravillous cytotrophoblast cells of the human placenta

(2011) U. Kämmerer et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Expression of the Human Endogenous Retrovirus (HERV) Group HML-2/HERV-K Does Not Depend on Canonical Promoter Elements but Is Regulated by Transcription Factors Sp1 and Sp3

(2011) N. V. Fuchs et al.   JOURNAL OF VIROLOGY

Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin

(2011) Kateřina Trejbalová et al.   NUCLEIC ACIDS RESEARCH

Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes

(2011) Ulrike Beyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced Expression of Both Syncytin 1 and Syncytin 2 Correlates With Severity of Preeclampsia

(2011) Amandine Vargas et al.   Reproductive Sciences

Silencing of endogenous retroviruses: when and why do histone marks predominate?

(2011) Danny C. Leung et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation

(2010) Sven Stengel et al.   GENES CHROMOSOMES & CANCER

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Depletion of Embryonic Stem Cell Signature by Histone Deacetylase Inhibitor in NCCIT Cells: Involvement of Nanog Suppression

(2009) J. S. You et al.   CANCER RESEARCH

Loss of epigenetic silencing in tumors preferentially affects primate-specific retroelements

(2009) Sebastian Szpakowski et al.   GENE

Endogenous retroviral LTRs as promoters for human genes: A critical assessment

(2009) Carla J. Cohen et al.   GENE

Integration target site selection by a resurrected human endogenous retrovirus

(2009) T. Brady et al.   GENES & DEVELOPMENT

Nucleosome positioning and gene regulation: advances through genomics

(2009) Cizhong Jiang et al.   NATURE REVIEWS GENETICS

Endogenous retroviruses

(2008) I. A. Maksakova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Endogenous retroviruses

(2008) C. Stocking et al.   CELLULAR AND MOLECULAR LIFE SCIENCES