Parasite-Microbiota Interactions With the Vertebrate Gut: Synthesis Through an Ecological Lens

Rapid environmental effects on gut nematode susceptibility in rewilded mice

(2018) Jacqueline M. Leung et al.   PLOS BIOLOGY

Feeding Immunity: Physiological and Behavioral Responses to Infection and Resource Limitation

(2018) Sarah A. Budischak et al.   Frontiers in Immunology

Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia

(2018) Bruce A. Rosa et al.   Microbiome

Manipulation of host and parasite microbiotas: Survival strategies during chronic nematode infection

(2018) Emily C. White et al.   Science Advances

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages

(2017) Raquel Alvarado et al.   FASEB JOURNAL

Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition

(2017) Michail Mamantopoulos et al.   IMMUNITY

This Gut Ain’t Big Enough for Both of Us. Or Is It? Helminth–Microbiota Interactions in Veterinary Species

(2017) Laura E. Peachey et al.   TRENDS IN PARASITOLOGY

Pathogenic Mechanisms of Cryptosporidium and Giardia

(2017) Gabriela Certad et al.   TRENDS IN PARASITOLOGY

The comparative immunology of wild and laboratory mice, Mus musculus domesticus

(2017) Stephen Abolins et al.   Nature Communications

Metacoder: An R package for visualization and manipulation of community taxonomic diversity data

(2017) Zachary S. L. Foster et al.   PLoS Computational Biology

Impact of Enterobius vermicularis infection and mebendazole treatment on intestinal microbiota and host immune response

(2017) Chin-An Yang et al.   PLoS Neglected Tropical Diseases

Microbiome Helper: a Custom and Streamlined Workflow for Microbiome Research

(2017) André M. Comeau et al.   mSystems

Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition

(2017) Timothy P. Jenkins et al.   PLoS One

A benign helminth alters the host immune system and the gut microbiota in a rat model system

(2017) Laura Wegener Parfrey et al.   PLoS One

Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome

(2016) Aleksey Chudnovskiy et al.   CELL

Macrobiota — helminths as active participants and partners of the microbiota in host intestinal homeostasis

(2016) William C Gause et al.   CURRENT OPINION IN MICROBIOLOGY

Kinetics of acute infection with Toxoplasma gondii and histopathological changes in the duodenum of rats

(2016) Aline Rosa Trevizan et al.   EXPERIMENTAL PARASITOLOGY

Role of Serum Amyloid A, Granulocyte-Macrophage Colony-Stimulating Factor, and Bone Marrow Granulocyte-Monocyte Precursor Expansion in Segmented Filamentous Bacterium-Mediated Protection from Entamoeba histolytica

(2016) Stacey L. Burgess et al.   INFECTION AND IMMUNITY

The microbiota in adaptive immune homeostasis and disease

(2016) Kenya Honda et al.   NATURE

Interactions between the microbiota and pathogenic bacteria in the gut

(2016) Andreas J. Bäumler et al.   NATURE

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids

(2016) Jung-ha Park et al.   PLoS One

Helminth infection promotes colonization resistance via type 2 immunity

(2016) Deepshika Ramanan et al.   SCIENCE

Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J. infection

(2016) Nan Meng et al.   Oncotarget

The effect of helminth infection on the microbial composition and structure of the caprine abomasal microbiome

(2016) Robert W. Li et al.   Scientific Reports

Colonization with the enteric protozoa Blastocystis is associated with increased diversity of human gut bacterial microbiota

(2016) Christophe Audebert et al.   Scientific Reports

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling

(2015) Maayan Levy et al.   CELL

Induction of Sda-sialomucin and sulfated H-sulfomucin in mouse small intestinal mucosa by infection with parasitic helminth

(2015) Daigo Tsubokawa et al.   EXPERIMENTAL PARASITOLOGY

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

(2015) Mario M. Zaiss et al.   IMMUNITY

Differences in the faecal microbiome of non-diarrhoeic clinically healthy dogs and cats associated with Giardia duodenalis infection: impact of hookworms and coccidia

(2015) Jan Šlapeta et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Marked seasonal variation in the wild mouse gut microbiota

(2015) Corinne F Maurice et al.   ISME Journal

Digestive tract mycobiota: A source of infection

(2015) N. Gouba et al.   MEDECINE ET MALADIES INFECTIEUSES

Helminths and the microbiota: parts of the hygiene hypothesis

(2015) P. Loke et al.   PARASITE IMMUNOLOGY

Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis

(2015) Nermina Vejzagić et al.   Parasites & Vectors

Suppression of inflammation by helminths: a role for the gut microbiota?

(2015) Paul Giacomin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Interactions between multiple helminths and the gut microbiota in wild rodents

(2015) Jakub Kreisinger et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The microbiota regulates type 2 immunity through ROR t+ T cells

(2015) C. Ohnmacht et al.   SCIENCE

Opposite effects of anthelmintic treatment on microbial infection at individual versus population scales

(2015) V. O. Ezenwa et al.   SCIENCE

Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence

(2015) Elise R. Morton et al.   PLoS Genetics

Are Human Intestinal Eukaryotes Beneficial or Commensals?

(2015) Julius Lukeš et al.   PLoS Pathogens

Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis

(2015) W. Florian Fricke et al.   Microbiome

Mucin glycan foraging in the human gut microbiome

(2015) Louise E. Tailford et al.   Frontiers in Genetics

Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance

(2015) Ashley Houlden et al.   PLoS One

Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli

(2015) Jacob Bak Holm et al.   PLoS One

The Earth Microbiome project: successes and aspirations

(2014) Jack A Gilbert et al.   BMC BIOLOGY

The composition of the gut microbiota shapes the colon mucus barrier

(2014) H. E. Jakobsson et al.   EMBO REPORTS

Coinfection with an Intestinal Helminth Impairs Host Innate Immunity against Salmonella enterica Serovar Typhimurium and Exacerbates Intestinal Inflammation in Mice

(2014) Libo Su et al.   INFECTION AND IMMUNITY

Helminth therapy or elimination: epidemiological, immunological, and clinical considerations

(2014) Linda J Wammes et al.   LANCET INFECTIOUS DISEASES

Gastrointestinal microbiota of wild and inbred individuals of two house mouse subspecies assessed using high-throughput parallel pyrosequencing

(2014) Jakub Kreisinger et al.   MOLECULAR ECOLOGY

Border maneuvers: deployment of mucosal immune defenses against Toxoplasma gondii

(2014) S B Cohen et al.   Mucosal Immunology

Persistent gut microbiota immaturity in malnourished Bangladeshi children

(2014) Sathish Subramanian et al.   NATURE

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Apicomplexan infections in the gut

(2014) C. L. Wilhelm et al.   PARASITE IMMUNOLOGY

Childhood malnutrition and the intestinal microbiome

(2014) Anne V. Kane et al.   PEDIATRIC RESEARCH

Altered Mucus Glycosylation in Core 1 O-Glycan-Deficient Mice Affects Microbiota Composition and Intestinal Architecture

(2014) Felix Sommer et al.   PLoS One

EFFECT OF Bifidobacterium animalis ON MICE INFECTED WITH Strongyloides venezuelensis

(2014) Teresa Cristina Goulart Oliveira-Sequeira et al.   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO

Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

(2014) L. C. Osborne et al.   SCIENCE

Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii

(2014) G. Gorfu et al.   mBio

Bone Marrow Dendritic Cells from Mice with an Altered Microbiota Provide Interleukin 17A-Dependent Protection against Entamoeba histolytica Colitis

(2014) Stacey L. Burgess et al.   mBio

What is a pathogen? Toward a process view of host-parasite interactions

(2014) Pierre-Olivier Méthot et al.   Virulence

The stunting syndrome in developing countries

(2014) Andrew J. Prendergast et al.   Paediatrics and International Child Health

Helminth Colonization Is Associated with Increased Diversity of the Gut Microbiota

(2014) Soo Ching Lee et al.   PLoS Neglected Tropical Diseases

Diarrhea in Early Childhood: Short-term Association With Weight and Long-term Association With Length

(2013) S. A. Richard et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Anthelmintic treatment alters the parasite community in a wild mouse host

(2013) A. B. Pedersen et al.   Biology Letters

Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome

(2013) Jordan L. Plieskatt et al.   FASEB JOURNAL

NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii

(2013) Sarah E. Ewald et al.   INFECTION AND IMMUNITY

Immunomodulation by helminth parasites: Defining mechanisms and mediators

(2013) Henry J. McSorley et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Persistent G. lamblia impairs growth in a murine malnutrition model

(2013) Luther A. Bartelt et al.   JOURNAL OF CLINICAL INVESTIGATION

Probiotics, gut microbiota and health

(2013) M.-J. Butel   MEDECINE ET MALADIES INFECTIEUSES

Macroparasites at peripheral sites of infection are major and dynamic modifiers of systemic antimicrobial pattern recognition responses

(2013) I. M. Friberg et al.   MOLECULAR ECOLOGY

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

(2013) Koji Atarashi et al.   NATURE

Effect of helminth-induced immunity on infections with microbial pathogens

(2013) Padmini Salgame et al.   NATURE IMMUNOLOGY

Small Intestinal Nematode Infection of Mice Is Associated with Increased Enterobacterial Loads alongside the Intestinal Tract

(2013) Sebastian Rausch et al.   PLoS One

Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota

(2013) Philip Cooper et al.   PLoS One

Stability of within-host-parasite communities in a wild mammal system

(2013) S. C. L. Knowles et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

(2013) M. I. Smith et al.   SCIENCE

Persistent gut barrier damage and commensal bacterial influx following eradication of Giardia infection in mice

(2013) Tzu-Ling Chen et al.   Gut Pathogens

IL-22 Mediates Goblet Cell Hyperplasia and Worm Expulsion in Intestinal Helminth Infection

(2013) Jan-Eric Turner et al.   PLoS Pathogens

IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity

(2013) Mario M. Zaiss et al.   PLoS Pathogens

Alterations in the Porcine Colon Microbiota Induced by the Gastrointestinal Nematode Trichuris suis

(2012) Robert W. Li et al.   INFECTION AND IMMUNITY

A new role for mucins in immunity: Insights from gastrointestinal nematode infection

(2012) Sumaira Z. Hasnain et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

(2012) Megan Raetz et al.   NATURE IMMUNOLOGY

Techniques used to characterize the gut microbiota: a guide for the clinician

(2012) Marianne H. Fraher et al.   Nature Reviews Gastroenterology & Hepatology

Worm Burden-Dependent Disruption of the Porcine Colon Microbiota by Trichuris suis Infection

(2012) Sitao Wu et al.   PLoS One

Inflammation Drives Dysbiosis and Bacterial Invasion in Murine Models of Ileal Crohn’s Disease

(2012) Melanie Craven et al.   PLoS One

Acute Gastrointestinal Infection Induces Long-Lived Microbiota-Specific T Cell Responses

(2012) T. W. Hand et al.   SCIENCE

Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria

(2012) G. F. Sonnenberg et al.   SCIENCE

The Human Gut Microbiota and Undernutrition

(2012) J. I. Gordon et al.   Science Translational Medicine

Helminthic therapy: improving mucosal barrier function

(2012) Martin J. Wolff et al.   TRENDS IN PARASITOLOGY

Asthma Prevention byLactobacillus Rhamnosusin a Mouse Model is Associated With CD4+CD25+Foxp3+T Cells

(2012) Seong-Ok Jang et al.   Allergy Asthma & Immunology Research

Evidence of Microbial Translocation Associated with Perturbations in T Cell and Antigen-Presenting Cell Homeostasis in Hookworm Infections

(2012) Palakkal Jovvian George et al.   PLoS Neglected Tropical Diseases

Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon

(2012) Mara Jana Broadhurst et al.   PLoS Pathogens

Defense peptides secreted by helminth pathogens: antimicrobial and/or immunomodulator molecules?

(2012) Sophie Cotton et al.   Frontiers in Immunology

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Contribution of Enteric Infection, Altered Intestinal Barrier Function, and Maternal Malnutrition to Infant Malnutrition in Bangladesh

(2011) D. Mondal et al.   CLINICAL INFECTIOUS DISEASES

Hymenolepis diminuta: Analysis of the expression of Toll-like receptor genes (TLR2 and TLR4) in the small and large intestines of rats

(2011) D.I. Kosik-Bogacka et al.   EXPERIMENTAL PARASITOLOGY

Duodenal Helminth Infection Alters Barrier Function of the Colonic Epithelium via Adaptive Immune Activation

(2011) Chien-wen Su et al.   INFECTION AND IMMUNITY

The effect of helminth co-infection on malaria in mice: A meta-analysis

(2011) Sarah C.L. Knowles   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Muc5ac: a critical component mediating the rejection of enteric nematodes

(2011) Sumaira Z. Hasnain et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of Venom Allergen-Like (VAL) proteins

(2011) James P. Hewitson et al.   Journal of Proteomics

In vitro and in vivo effects of Enterococcus faecalis CECT7121 on Toxocara canis

(2011) Paula G Chiodo et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

The intraperitoneal inoculation of Lactobacillus casei in mice induces total protection against Trichinella spiralis infection at low challenge doses

(2011) Federico Martínez-Gómez et al.   PARASITOLOGY RESEARCH

A Family of Helminth Molecules that Modulate Innate Cell Responses via Molecular Mimicry of Host Antimicrobial Peptides

(2011) Mark W. Robinson et al.   PLoS Pathogens

Microbial Eukaryotes in the Human Microbiome: Ecology, Evolution, and Future Directions

(2011) Laura Wegener Parfrey et al.   Frontiers in Microbiology

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Detecting interspecific macroparasite interactions from ecological data: patterns and process

(2010) Andy Fenton et al.   ECOLOGY LETTERS

Alteration of the murine gut microbiota during infection with the parasitic helminth Heligmosomoides polygyrus

(2010) Seth T. Walk et al.   INFLAMMATORY BOWEL DISEASES

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

(2010) John R. Grainger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gut inflammation provides a respiratory electron acceptor for Salmonella

(2010) Sebastian E. Winter et al.   NATURE

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

(2010) M. Ritter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploitation of the Intestinal Microflora by the Parasitic Nematode Trichuris muris

(2010) K. S. Hayes et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

(2010) M. J. Broadhurst et al.   Science Translational Medicine

Expulsion of Trichuris muris is associated with increased expression of angiogenin 4 in the gut and increased acidity of mucins within the goblet cell

(2009) Riccardo D'Elia et al.   BMC GENOMICS

Gut Commensal Bacteria Direct a Protective Immune Response against Toxoplasma gondii

(2009) Alicia Benson et al.   Cell Host & Microbe

Cryptosporidium Infection Causes Undernutrition and, Conversely, Weanling Undernutrition Intensifies Infection

(2009) Bruna P. Coutinho et al.   JOURNAL OF PARASITOLOGY

Effect of Lactobacillus casei Shirota strain intraperitoneal administration in CD1 mice on the establishment of Trichinella spiralis adult worms and on IgA anti-T. spiralis production

(2009) Federico Martínez-Gómez et al.   VETERINARY PARASITOLOGY

Lactobacillus delbrueckii ssp. bulgaricus B-30892 can inhibit cytotoxic effects and adhesion of pathogenic Clostridium difficile to Caco-2 cells

(2009) Pratik Banerjee et al.   Gut Pathogens

Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites

(2008) R. T. Semnani et al.   BLOOD

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Effect of Lactobacillus casei as a Probiotic on Modulation of Giardiasis

(2008) Geeta Shukla et al.   DIGESTIVE DISEASES AND SCIENCES

Review series on helminths, immune modulation and the hygiene hypothesis: Immunity against helminths and immunological phenomena in modern human populations: coevolutionary legacies?

(2008) Joseph A. Jackson et al.   IMMUNOLOGY

Schistosoma mansoni Egg Antigen-Mediated Modulation of Toll-Like Receptor (TLR)-Induced Activation Occurs Independently of TLR2, TLR4, and MyD88

(2008) C. M. Kane et al.   INFECTION AND IMMUNITY

Multi-country analysis of the effects of diarrhoea on childhood stunting

(2008) William Checkley et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Ecological rules governing helminth microparasite coinfection

(2008) A. L. Graham   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Interplay between Entamoeba and Enteropathogenic Bacteria Modulates Epithelial Cell Damage

(2008) José Manuel Galván-Moroyoqui et al.   PLoS Neglected Tropical Diseases

Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation

(2008) Caitlin O'Mahony et al.   PLoS Pathogens

Enhanced susceptibility to Trichuris muris infection of B10Br mice treated with the probiotic Lactobacillus casei

(2007) Ma Auxiliadora Dea-Ayuela et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Coccidia-induced mucogenesis promotes the onset of necrotic enteritis by supporting Clostridium perfringens growth

(2007) C.T. Collier et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY