Dengue Virus Capsid Interacts with DDX3X–A Potential Mechanism for Suppression of Antiviral Functions in Dengue Infection

N-Desmethylclozapine, Fluoxetine, and Salmeterol Inhibit Postentry Stages of the Dengue Virus Life Cycle

(2016) Guruprasad R. Medigeshi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tyrosine phosphorylation modulates mitochondrial chaperonin Hsp60 and delays rotavirus NSP4-mediated apoptotic signaling in host cells

(2016) Shiladitya Chattopadhyay et al.   CELLULAR MICROBIOLOGY

Dengue virus non-structural 1 protein interacts with heterogeneous nuclear ribonucleoprotein H in human monocytic cells

(2016) Drishya Diwaker et al.   Asian Pacific Journal of Tropical Medicine

Properties and Functions of the Dengue Virus Capsid Protein

(2016) Laura A. Byk et al.   Annual Review of Virology

Identification and characterization of the role of c-terminal Src kinase in dengue virus replication

(2016) Rinki Kumar et al.   Scientific Reports

DEAD-box RNA helicase DDX3X inhibits DENV replication via regulating type one interferon pathway

(2015) Guanghao Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting DDX3 with a small molecule inhibitor for lung cancer therapy

(2015) G. M. Bol et al.   EMBO Molecular Medicine

Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection

(2015) Véronique Pène et al.   JOURNAL OF VIROLOGY

RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity

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Role of human heterogeneous nuclear ribonucleoprotein C1/C2 in dengue virus replication

(2015) Thanyaporn Dechtawewat et al.   Virology Journal

The heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a host factor required for dengue virus and Junín virus multiplication

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West Nile virus and dengue virus capsid protein negates the antiviral activity of human Sec3 protein through the proteasome pathway

(2013) Raghavan Bhuvanakantham et al.   CELLULAR MICROBIOLOGY

Nucleolin Interacts with the Dengue Virus Capsid Protein and Plays a Role in Formation of Infectious Virus Particles

(2013) C. A. Balinsky et al.   JOURNAL OF VIROLOGY

The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA

(2013) Ricardo Soto-Rifo et al.   NUCLEIC ACIDS RESEARCH

Identification of New Protein Interactions between Dengue Fever Virus and Its Hosts, Human and Mosquito

(2013) Dumrong Mairiang et al.   PLoS One

Human DDX3 Interacts with the HIV-1 Tat Protein to Facilitate Viral mRNA Translation

(2013) Ming-Chih Lai et al.   PLoS One

Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions

(2013) Chen Li et al.   VIROLOGY

Sustained replication of dengue pseudoinfectious virus lacking the capsid gene by trans-complementation in capsid-producing mosquito cells

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Adaptor protein complexes-1 and 3 are involved at distinct stages of flavivirus life-cycle

(2013) Tanvi Agrawal et al.   Scientific Reports

Bispidine-Amino Acid Conjugates Act as a Novel Scaffold for the Design of Antivirals That Block Japanese Encephalitis Virus Replication

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The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism

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ATP Utilization and RNA Conformational Rearrangement by DEAD-Box Proteins

(2012) Arnon Henn et al.   Annual Review of Biophysics

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

(2012) Manohar Pilli et al.   IMMUNITY

Japanese Encephalitis Virus Core Protein Inhibits Stress Granule Formation through an Interaction with Caprin-1 and Facilitates Viral Propagation

(2012) H. Katoh et al.   JOURNAL OF VIROLOGY

Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life Cycle

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The West Nile Virus Capsid Protein Blocks Apoptosis through a Phosphatidylinositol 3-Kinase-Dependent Mechanism

(2012) M. D. Urbanowski et al.   JOURNAL OF VIROLOGY

P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication

(2012) Harendra S. Chahar et al.   VIROLOGY

Viruses and the human DEAD-box helicase DDX3: inhibition or exploitation?: Figure 1

(2011) Martina Schröder   BIOCHEMICAL SOCIETY TRANSACTIONS

Targeting the Human DEAD-Box Polypeptide 3 (DDX3) RNA Helicase as a Novel Strategy to Inhibit Viral Replication

(2011) A. Garbelli et al.   CURRENT MEDICINAL CHEMISTRY

Mosquito-borne flaviviruses: overview of viral life-cycle and host–virus interactions

(2011) Guruprasad R Medigeshi   Future Virology

Hepatitis C Virus Hijacks P-Body and Stress Granule Components around Lipid Droplets

(2011) Y. Ariumi et al.   JOURNAL OF VIROLOGY

A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication

(2011) Anna Garbelli et al.   PLoS One

Dengue Virus Capsid Protein Binds Core Histones and Inhibits Nucleosome Formation in Human Liver Cells

(2011) Tonya M. Colpitts et al.   PLoS One

TBK1 Mediates Crosstalk Between the Innate Immune Response and Autophagy

(2011) H. Weidberg et al.   Science Signaling

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential

(2010) Hiroyuki Oshiumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Unexpected roles for DEAD-box protein 3 in viral RNA sensing pathways

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The Ubiquitin−Proteasome Pathway Is Important for Dengue Virus Infection in Primary Human Endothelial Cells

(2010) Rattiyaporn Kanlaya et al.   JOURNAL OF PROTEOME RESEARCH

Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction

(2010) Hiroyuki Oshiumi et al.   PLoS One

Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion

(2010) Haifeng Wang et al.   PLoS Pathogens

Specific interaction of capsid protein and importin-α/β influences West Nile virus production

(2009) Raghavan Bhuvanakantham et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments

(2009) Alexandre J.C. Quaresma et al.   EXPERIMENTAL CELL RESEARCH

RNA interference mediated silencing of Hsp60 gene in human monocytic myeloma cell line U937 revealed decreased dengue virus multiplication

(2009) Y.S. Padwad et al.   IMMUNOBIOLOGY

Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein

(2009) A. G. N. Angus et al.   JOURNAL OF GENERAL VIROLOGY

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

(2009) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosis

(2009) Janjuree Netsawang et al.   VIRUS RESEARCH

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

(2008) Didier Soulat et al.   EMBO JOURNAL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

Multiple regions in dengue virus capsid protein contribute to nuclear localization during virus infection

(2008) S. Sangiambut et al.   JOURNAL OF GENERAL VIROLOGY

Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3

(2008) Arnout P. Kalverda et al.   JOURNAL OF MOLECULAR BIOLOGY

The DEAD-Box RNA Helicase DDX3 Associates with Export Messenger Ribonucleoproteins as well asTip-associated Protein and Participates in Translational Control

(2008) Ming-Chih Lai et al.   MOLECULAR BIOLOGY OF THE CELL