Tyrosine phosphorylation modulates mitochondrial chaperonin Hsp60 and delays rotavirus NSP4-mediated apoptotic signaling in host cells

Rotavirus-induced miR-142-5p elicits proviral milieu by targeting non-canonical transforming growth factor beta signalling and apoptosis in cells

(2015) Shampa Chanda et al.   CELLULAR MICROBIOLOGY

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

(2015) Y.-C. Lai et al.   EMBO JOURNAL

Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response

(2015) Hao Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative phosphoproteomics reveals crosstalk between phosphorylation andO-GlcNAc in the DNA damage response pathway

(2015) Jun Zhong et al.   PROTEOMICS

Phosphoproteome characterization reveals that Sendai virus infection activates mTOR signaling in human epithelial cells

(2015) Tiina Öhman et al.   PROTEOMICS

The tight junction protein JAM-A functions as coreceptor for rotavirus entry into MA104 cells

(2015) Jesús M. Torres-Flores et al.   VIROLOGY

Phosphoproteomics Combined with Quantitative 14-3-3-affinity Capture Identifies SIRT1 and RAI as Novel Regulators of Cytosolic Double-stranded RNA Recognition Pathway

(2014) Tiina Öhman et al.   MOLECULAR & CELLULAR PROTEOMICS

Phosphoproteome mapping of cardiomyocyte mitochondria in a rat model of heart failure

(2014) Francesco Giorgianni et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells

(2014) T. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rotavirus infection induces G1 to S phase transition in MA104 cells via Ca+2/Calmodulin pathway

(2014) Rahul Bhowmick et al.   VIROLOGY

Cardiac Phosphoproteomics during Remote Ischemic Preconditioning: A Role for the Sarcomeric Z-Disk Proteins

(2014) Safa Abdul-Ghani et al.   Biomed Research International

Quantitative Phosphoproteomics Reveals Extensive Cellular Reprogramming during HIV-1 Entry

(2013) Jason A. Wojcechowskyj et al.   Cell Host & Microbe

Identification of Cellular Calcium Binding Protein Calmodulin as a Regulator of Rotavirus A Infection during Comparative Proteomic Study

(2013) Shiladitya Chattopadhyay et al.   PLoS One

Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry

(2013) D. Silva-Ayala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition

(2013) D. S. Kirkpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo SILAC-Based Proteomics Reveals Phosphoproteome Changes during Mouse Skin Carcinogenesis

(2013) Sara Zanivan et al.   Cell Reports

HSP60 as a Drug Target

(2012) Hiroyuki Nakamura et al.   CURRENT PHARMACEUTICAL DESIGN

Rotaviral Enterotoxin Nonstructural Protein 4 Targets Mitochondria for Activation of Apoptosis during Infection

(2012) Rahul Bhowmick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanism behind Rotavirus NSP1-Mediated PI3 Kinase Activation: Interaction between NSP1 and the p85 Subunit of PI3 Kinase

(2012) P. Bagchi et al.   JOURNAL OF VIROLOGY

Conformational Switching of the Molecular Chaperone Hsp90 via Regulated Phosphorylation

(2012) Joanna Soroka et al.   MOLECULAR CELL

Post-translational modifications of Hsp90 and their contributions to chaperone regulation

(2011) Mehdi Mollapour et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Active Participation of Cellular Chaperone Hsp90 in Regulating the Function of Rotavirus Nonstructural Protein 3 (NSP3)

(2011) Dipanjan Dutta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rotavirus Infection Induces the Unfolded Protein Response of the Cell and Controls It through the Nonstructural Protein NSP3

(2011) V. Trujillo-Alonso et al.   JOURNAL OF VIROLOGY

Replication of the Rotavirus Genome Requires an Active Ubiquitin-Proteasome System

(2011) T. Lopez et al.   JOURNAL OF VIROLOGY

A Systematic Analysis of Eluted Fraction of Plasma Post Immunoaffinity Depletion: Implications in Biomarker Discovery

(2011) Amit Kumar Yadav et al.   PLoS One

Quantitative phosphoproteomics of transforming growth factor-β signaling in colon cancer cells

(2011) Naveid A. Ali et al.   PROTEOMICS

Phosphorylation in Protein-Protein Binding: Effect on Stability and Function

(2011) Hafumi Nishi et al.   STRUCTURE

Rotavirus infection activates the UPR but modulates its activity

(2011) Jose Zambrano et al.   Virology Journal

Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ

(2010) Parvathi Rudrabhatla et al.   FASEB JOURNAL

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

The mitochondrial UPR - protecting organelle protein homeostasis

(2010) C. M. Haynes et al.   JOURNAL OF CELL SCIENCE

Degradation of an intramitochondrial protein by the cytosolic proteasome

(2010) V. Azzu et al.   JOURNAL OF CELL SCIENCE

Rotaviruses Associate with Cellular Lipid Droplet Components To Replicate in Viroplasms, and Compounds Disrupting or Blocking Lipid Droplets Inhibit Viroplasm Formation and Viral Replication

(2010) W. Cheung et al.   JOURNAL OF VIROLOGY

Rotavirus Nonstructural Protein 1 Suppresses Virus-Induced Cellular Apoptosis To Facilitate Viral Growth by Activating the Cell Survival Pathways during Early Stages of Infection

(2010) P. Bagchi et al.   JOURNAL OF VIROLOGY

Gymnastics of Molecular Chaperones

(2010) Matthias P. Mayer   MOLECULAR CELL

Phospho.ELM: a database of phosphorylation sites--update 2011

(2010) H. Dinkel et al.   NUCLEIC ACIDS RESEARCH

Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: A mass spectrometric approach

(2010) Veerle De Corte et al.   PROTEIN SCIENCE

Rotavirus Disrupts Calcium Homeostasis by NSP4 Viroporin Activity

(2010) J. M. Hyser et al.   mBio

Amyloid precursor protein, heat-shock proteins, and Bcl-2 form a complex in mitochondria and modulate mitochondria function and apoptosis in N2a cells

(2009) Ting-Ting Yang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The molecular chaperone heat shock protein-90 positively regulates rotavirus infection

(2009) Dipanjan Dutta et al.   VIROLOGY

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

Global and Site-Specific Quantitative Phosphoproteomics: Principles and Applications

(2008) Boris Macek et al.   Annual Review of Pharmacology and Toxicology

Mitochondrial Protein Quality Control by the Proteasome Involves Ubiquitination and the Protease Omi

(2008) Susanne Radke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation

(2008) Elena Tibaldi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Vicious Cycle Involving Release of Heat Shock Protein 60 from Injured Cells and Activation of Toll-Like Receptor 4 Mediates Neurodegeneration in the CNS

(2008) S. Lehnardt et al.   JOURNAL OF NEUROSCIENCE

Silencing of Rotavirus NSP4 or VP7 Expression Reduces Alterations in Ca2+ Homeostasis Induced by Infection of Cultured Cells

(2008) J. L. Zambrano et al.   JOURNAL OF VIROLOGY

Expression of Nonstructural Rotavirus Protein NSP4 Mimics Ca2+ Homeostasis Changes Induced by Rotavirus Infection in Cultured Cells

(2008) Y. Diaz et al.   JOURNAL OF VIROLOGY

Src family kinases: Regulation of their activities, levels and identification of new pathways

(2007) Evan Ingley   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS