The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism

The eukaryotic transcriptional machinery regulates mRNA translation and decay in the cytoplasm

(2012) Nili Dahan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

(2012) Ricardo Soto-Rifo et al.   EMBO JOURNAL

Modulation of the type I interferon pathways by culture-adaptive hepatitis C virus core mutants

(2012) Ju-Il Kang et al.   FEBS LETTERS

Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life Cycle

(2012) S. Vashist et al.   JOURNAL OF VIROLOGY

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

(2012) Trevor J. Pugh et al.   NATURE

Novel mutations target distinct subgroups of medulloblastoma

(2012) Giles Robinson et al.   NATURE

The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes

(2012) Rene Geissler et al.   NUCLEIC ACIDS RESEARCH

Gene Expression Analysis in Human Breast Cancer Associated Blood Vessels

(2012) Dylan T. Jones et al.   PLoS One

Toward a molecular understanding of RNA remodeling by DEAD-box proteins

(2012) Rick Russell et al.   RNA Biology

P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication

(2012) Harendra S. Chahar et al.   VIROLOGY

Viruses and the human DEAD-box helicase DDX3: inhibition or exploitation?: Figure 1

(2011) Martina Schröder   BIOCHEMICAL SOCIETY TRANSACTIONS

Promoter Elements Regulate Cytoplasmic mRNA Decay

(2011) Almog Bregman et al.   CELL

Single-Molecule mRNA Decay Measurements Reveal Promoter- Regulated mRNA Stability in Yeast

(2011) Tatjana Trcek et al.   CELL

Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation

(2011) Giovanni Maga et al.   ChemMedChem

Reduced p21WAF1/CIP1 via Alteration of p53-DDX3 Pathway Is Associated with Poor Relapse-Free Survival in Early-Stage Human Papillomavirus-Associated Lung Cancer

(2011) D.-W. Wu et al.   CLINICAL CANCER RESEARCH

RNA helicases and remodeling proteins

(2011) Anna Marie Pyle   CURRENT OPINION IN CHEMICAL BIOLOGY

HIV-1 remodels the nuclear pore complex

(2011) Anne Monette et al.   JOURNAL OF CELL BIOLOGY

The DEAD-box RNA helicase DDX3 interacts with DDX5, co-localizes with it in the cytoplasm during the G2/M phase of the cycle, and affects its shuttling during mRNP export

(2011) Yeo-Jin Choi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production

(2011) Souad Naji et al.   MOLECULAR & CELLULAR PROTEOMICS

The DEAD-Box Protein Ded1 Modulates Translation by the Formation and Resolution of an eIF4F-mRNA Complex

(2011) Angela Hilliker et al.   MOLECULAR CELL

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Different effects of the TAR structure on HIV-1 and HIV-2 genomic RNA translation

(2011) R. Soto-Rifo et al.   NUCLEIC ACIDS RESEARCH

A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication

(2011) Anna Garbelli et al.   PLoS One

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Pre-mRNA splicing: where and when in the nucleus

(2011) Joonhee Han et al.   TRENDS IN CELL BIOLOGY

The RNA Worlds in Context

(2011) T. R. Cech   Cold Spring Harbor Perspectives in Biology

Stepwise translocation of nucleic acid motors

(2010) Sua Myong et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

SF1 and SF2 helicases: family matters

(2010) Margaret E Fairman-Williams et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning

(2010) Irina S Abaeva et al.   EMBO JOURNAL

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential

(2010) Hiroyuki Oshiumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

DDX3 Regulates Cell Growth through Translational Control of Cyclin E1

(2010) M.-C. Lai et al.   MOLECULAR AND CELLULAR BIOLOGY

The RNA helicase database

(2010) A. Jankowsky et al.   NUCLEIC ACIDS RESEARCH

Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction

(2010) Hiroyuki Oshiumi et al.   PLoS One

The current understanding of Ded1p/DDX3 homologs from yeast to human

(2010) Woan-Yuh Tarn et al.   RNA Biology

RNA helicases at work: binding and rearranging

(2010) Eckhard Jankowsky   TRENDS IN BIOCHEMICAL SCIENCES

The Origins of the RNA World

(2010) M. P. Robertson et al.   Cold Spring Harbor Perspectives in Biology

Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion

(2010) Haifeng Wang et al.   PLoS Pathogens

DEAD-box proteins as RNA helicases and chaperones

(2010) Inga Jarmoskaite et al.   Wiley Interdisciplinary Reviews-RNA

Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulation

(2009) Martina Schröder   BIOCHEMICAL PHARMACOLOGY

Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation

(2009) Melissa J. Moore et al.   CELL

mRNA Localization: Gene Expression in the Spatial Dimension

(2009) Kelsey C. Martin et al.   CELL

Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

(2009) Ivan Topisirovic et al.   EMBO JOURNAL

Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein

(2009) A. G. N. Angus et al.   JOURNAL OF GENERAL VIROLOGY

RNA granules: post-transcriptional and epigenetic modulators of gene expression

(2009) Paul Anderson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

How RNA Unfolds and Refolds

(2008) Pan T.X. Li et al.   Annual Review of Biochemistry

Translocation and Unwinding Mechanisms of RNA and DNA Helicases

(2008) Anna Marie Pyle   Annual Review of Biophysics

EJCs at the Heart of Translational Control

(2008) Hervé Le Hir et al.   CELL

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

(2008) Didier Soulat et al.   EMBO JOURNAL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

The DEAD-Box RNA Helicase DDX3 Associates with Export Messenger Ribonucleoproteins as well asTip-associated Protein and Participates in Translational Control

(2008) Ming-Chih Lai et al.   MOLECULAR BIOLOGY OF THE CELL

Non-hexameric DNA helicases and translocases: mechanisms and regulation

(2008) Timothy M. Lohman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human DDX3 functions in translation and interacts with the translation initiation factor eIF3

(2008) C.-S. Lee et al.   NUCLEIC ACIDS RESEARCH

Oncogenic role of DDX3 in breast cancer biogenesis

(2008) M Botlagunta et al.   ONCOGENE

DEAD-box proteins can completely separate an RNA duplex using a single ATP

(2008) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

(2008) F. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES

The DEAD-Box RNA Helicase Ded1p Affects and Accumulates in Saccharomyces cerevisiae P-Bodies

(2007) Carla Beckham et al.   MOLECULAR BIOLOGY OF THE CELL