Tumor initiating cells induce Cxcr4-mediated infiltration of pro-tumoral macrophages into the brain

Involvement of the phosphoinositide 3-kinase/Akt signaling pathway in bone morphogenetic protein 9-stimulated osteogenic differentiation and stromal cell-derived factor 1 production in human periodontal ligament fibroblasts

(2017) Kirara Furue et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme

(2017) Vincenzo Torraca et al.   Scientific Reports

Spinal motor neurons are regenerated after mechanical lesion and genetic ablation in larval zebrafish

(2016) Jochen Ohnmacht et al.   DEVELOPMENT

Microglia Colonization of Developing Zebrafish Midbrain Is Promoted by Apoptotic Neuron and Lysophosphatidylcholine

(2016) Jin Xu et al.   DEVELOPMENTAL CELL

A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth

(2016) Marie Mayrhofer et al.   Disease Models & Mechanisms

Identification of a conserved and acute neurodegeneration-specific microglial transcriptome in the zebrafish

(2016) Nynke Oosterhof et al.   GLIA

Time lapsein vivomicroscopy reveals distinct dynamics of microglia-tumor environment interactions-a new role for the tumor perivascular space as highway for trafficking microglia

(2016) Simon Heinrich Bayerl et al.   GLIA

Microglial Physiology and Pathophysiology: Insights from Genome-wide Transcriptional Profiling

(2016) Andrea Crotti et al.   IMMUNITY

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

A Zebrafish Live Imaging Model Reveals Differential Responses of Microglia Toward Glioblastoma Cells In Vivo

(2016) Lloyd Hamilton et al.   Zebrafish

The Rag-Ragulator Complex Regulates Lysosome Function and Phagocytic Flux in Microglia

(2016) Kimberle Shen et al.   Cell Reports

Developmental Apoptosis Mediates Entry and Positioning of Microglia in the Zebrafish Brain

(2016) Alessandra Maria Casano et al.   Cell Reports

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies

(2016) Robert L. Bowman et al.   Cell Reports

Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice

(2016) Clément Ricard et al.   Scientific Reports

Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

(2015) R. Hughes et al.   CANCER RESEARCH

Microglia: Multitasking Specialists of the Brain

(2015) Alessandra Maria Casano et al.   DEVELOPMENTAL CELL

Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity

(2015) Alessandra M. Welker et al.   Disease Models & Mechanisms

Oncogenic KRAS promotes malignant brain tumors in zebrafish

(2015) Bensheng Ju et al.   Molecular Cancer

Macrophage depletion reduces postsurgical tumor recurrence and metastatic growth in a spontaneous murine model of melanoma

(2015) Muly Tham et al.   Oncotarget

PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions

(2015) Rosa Gómez-Villafuertes et al.   Scientific Reports

Differential Requirement for irf8 in Formation of Embryonic and Adult Macrophages in Zebrafish

(2015) Celia E. Shiau et al.   PLoS One

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype

(2015) Katia Beider et al.   Oncotarget

RETRACTED: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

(2014) Satish Srinivas Kitambi et al.   CELL

The role of CXCR4 in highly malignant human gliomas biology: Current knowledge and future directions

(2014) Filippo Gagliardi et al.   GLIA

Systemic inflammation regulates microglial responses to tissue damagein vivo

(2014) Stefka Gyoneva et al.   GLIA

Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages

(2014) Anna Carolina Carvalho da Fonseca et al.   JOURNAL OF NEUROIMMUNOLOGY

Orthotopic models of pediatric brain tumors in zebrafish

(2014) C J Eden et al.   ONCOGENE

Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia

(2014) Fargol Mazaheri et al.   Nature Communications

Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex

(2014) Benedetta Arnò et al.   Nature Communications

Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway

(2014) B Ju et al.   Oncogenesis

S100B Promotes Glioma Growth through Chemoattraction of Myeloid-Derived Macrophages

(2013) H. Wang et al.   CLINICAL CANCER RESEARCH

Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia

(2013) Aleksandra Ellert-Miklaszewska et al.   GLIA

Review: Molecular mechanism of microglia stimulated glioblastoma invasion

(2013) Salvatore J. Coniglio et al.   MATRIX BIOLOGY

PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling

(2013) M Conley-LaComb et al.   Molecular Cancer

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Glioma is formed by active Akt1 alone and promoted by active Rac1 in transgenic zebrafish

(2013) In Hye Jung et al.   NEURO-ONCOLOGY

A Novel Zebrafish Xenotransplantation Model for Study of Glioma Stem Cell Invasion

(2013) Xiao-jun Yang et al.   PLoS One

Quantitating the subtleties of microglial morphology with fractal analysis

(2013) Audrey Karperien et al.   Frontiers in Cellular Neuroscience

An Anti-inflammatory NOD-like Receptor Is Required for Microglia Development

(2013) Celia E. Shiau et al.   Cell Reports

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

Reciprocal Regulation between Resting Microglial Dynamics and Neuronal Activity In Vivo

(2012) Ying Li et al.   DEVELOPMENTAL CELL

Long-Range Ca2+ Waves Transmit Brain-Damage Signals to Microglia

(2012) Dirk Sieger et al.   DEVELOPMENTAL CELL

Development of ramified microglia from early macrophages in the zebrafish optic tectum

(2012) Adam J. Svahn et al.   Developmental Neurobiology

Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development

(2012) J. Shin et al.   Disease Models & Mechanisms

The molecular profile of microglia under the influence of glioma

(2012) W. Li et al.   NEURO-ONCOLOGY

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

(2012) D. Friedmann-Morvinski et al.   SCIENCE

Acute Inflammation Initiates the Regenerative Response in the Adult Zebrafish Brain

(2012) N. Kyritsis et al.   SCIENCE

A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis

(2011) J. Zhang et al.   CARCINOGENESIS

Calpain 2 is required for the invasion of glioblastoma cells in the zebrafish brain microenvironment

(2011) Sangeet Lal et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish

(2010) F. Ellett et al.   BLOOD

Microglia/macrophages promote glioma progression

(2010) Haiyan Zhai et al.   GLIA

Neurofibromatosis-1 Heterozygosity Increases Microglia in a Spatially and Temporally Restricted Pattern Relevant to Mouse Optic Glioma Formation and Growth

(2010) Grant W. Simmons et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

(2010) Adam Wu et al.   NEURO-ONCOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation

(2010) Yi Feng et al.   PLOS BIOLOGY

The role of microglia in central nervous system immunity and glioma immunology

(2009) Isaac Yang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Increased c-Jun-NH2-Kinase Signaling in Neurofibromatosis-1 Heterozygous Microglia Drives Microglia Activation and Promotes Optic Glioma Proliferation

(2008) G. C. Daginakatte et al.   CANCER RESEARCH

Temozolomide-Mediated Radiosensitization of Human Glioma Cells in a Zebrafish Embryonic System

(2008) G. A. Geiger et al.   CANCER RESEARCH

Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo

(2008) Francesca Peri et al.   CELL

Mifepristone-inducible LexPR system to drive and control gene expression in transgenic zebrafish

(2008) Alexander Emelyanov et al.   DEVELOPMENTAL BIOLOGY

Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas

(2008) Y Komohara et al.   JOURNAL OF PATHOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols