The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme

Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model

(2016) Claudia Tulotta et al.   Disease Models & Mechanisms

Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection

(2016) Mark R. Cronan et al.   IMMUNITY

Non-migratory tumorigenic intrinsic cancer stem cells ensure breast cancer metastasis by generation of CXCR4+ migrating cancer stem cells

(2016) S Mukherjee et al.   ONCOGENE

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

(2015) S. Massena et al.   BLOOD

Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche

(2015) Owen J. Tamplin et al.   CELL

The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection

(2015) V. Torraca et al.   Disease Models & Mechanisms

Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery

(2015) Meenal Datta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection and pathology in TB: learning from the zebrafish model

(2015) Annemarie H. Meijer   Seminars in Immunopathology

Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial‑to‑mesenchymal transition in colon and breast cancers

(2015) Venkat R. Katkoori et al.   Oncotarget

Transient infection of the zebrafish notochord with E. coli induces chronic inflammation

(2014) M. Nguyen-Chi et al.   Disease Models & Mechanisms

The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis

(2014) S. Gelmini et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Interception of host angiogenic signalling limits mycobacterial growth

(2014) Stefan H. Oehlers et al.   NATURE

Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation

(2014) A. Bernut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress–Induced Inflammation

(2014) Sergio Candel et al.   PLOS BIOLOGY

The role IL-1 in tumor-mediated angiogenesis

(2014) Elena Voronov et al.   Frontiers in Physiology

Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system

(2013) M. van der Vaart et al.   Disease Models & Mechanisms

The Role of IL-1  in the Early Tumor Cell-Induced Angiogenic Response

(2013) Y. Carmi et al.   JOURNAL OF IMMUNOLOGY

Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish

(2013) Kevin Takaki et al.   Nature Protocols

Migration of cardiomyocytes is essential for heart regeneration in zebrafish

(2012) J. Itou et al.   DEVELOPMENT

Chemokine Signaling Directs Trunk Lymphatic Network Formation along the Preexisting Blood Vasculature

(2012) Young Ryun Cha et al.   DEVELOPMENTAL CELL

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

(2012) Shuning He et al.   JOURNAL OF PATHOLOGY

Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis

(2011) Azucena López-Muñoz et al.   MOLECULAR IMMUNOLOGY

Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis

(2010) L. Li et al.   BLOOD

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

(2010) A. Fantin et al.   BLOOD

Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome

(2010) K. B. Walters et al.   BLOOD

Chemokine signaling in embryonic cell migration: a fisheye view

(2009) E. Raz et al.   DEVELOPMENT

Plerixafor, a CXCR4 antagonist for the mobilization of hematopoietic stem cells

(2008) Geoffrey L Uy et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A novel CXCR4 antagonist for hematopoietic stem cell mobilization

(2008) Simon P Fricker   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Neutrophil mobilization and clearance in the bone marrow

(2008) Rebecca C. Furze et al.   IMMUNOLOGY

CXCR4 signaling in the regulation of stem cell migration and development

(2008) Richard J. Miller et al.   JOURNAL OF NEUROIMMUNOLOGY

Chemokine receptor 4 (CXCR4) is part of the lipopolysaccharide “sensing apparatus”

(2007) Martha Triantafilou et al.   EUROPEAN JOURNAL OF IMMUNOLOGY