Cleavage activates Dispatched for Sonic Hedgehog ligand release

Hedgehog signalling

(2016) Raymond Teck Ho Lee et al.   DEVELOPMENT

Endocytosis of Hedgehog through Dispatched Regulates Long-Range Signaling

(2015) Gisela D’Angelo et al.   DEVELOPMENTAL CELL

Identification of a Family of Fatty-Acid-Speciated Sonic Hedgehog Proteins, Whose Members Display Differential Biological Properties

(2015) Jun Long et al.   Cell Reports

Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling

(2015) Suresh Marada et al.   PLoS Genetics

Regulation of TGFβ and related signals by precursor processing

(2014) Daniel B. Constam   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Multifaceted Proprotein Convertases: Their Unique, Redundant, Complementary, and Opposite Functions

(2013) Nabil G. Seidah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diet controlsDrosophilafollicle stem cell proliferation via Hedgehog sequestration and release

(2013) Tiffiney R. Hartman et al.   JOURNAL OF CELL BIOLOGY

The Unfolded Protein Response Selectively Targets Active Smoothened Mutants

(2013) S. Marada et al.   MOLECULAR AND CELLULAR BIOLOGY

The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation

(2012) C. E. Carroll et al.   DEVELOPMENT

Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form

(2012) A. Creanga et al.   GENES & DEVELOPMENT

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

Dispatched and Scube Mediate the Efficient Secretion of the Cholesterol-Modified Hedgehog Ligand

(2012) Hanna Tukachinsky et al.   Cell Reports

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium

(2011) A. Callejo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for a role of vertebrate Disp1 in long-range Shh signaling

(2009) L. A. Etheridge et al.   DEVELOPMENT

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL

Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation

(2008) Marie-Hélène Blanchet et al.   EMBO JOURNAL

In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate

(2008) R. Essalmani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cripto Localizes Nodal at the Limiting Membrane of Early Endosomes

(2008) M.-H. Blanchet et al.   Science Signaling