Paeoniflorin exerts neuroprotective effects by modulating the M1/M2 subset polarization of microglia/macrophages in the hippocampal CA1 region of vascular dementia rats via cannabinoid receptor 2

Cannabinoid receptor-2 stimulation suppresses neuroinflammation by regulating microglial M1/M2 polarization through the cAMP/PKA pathway in an experimental GMH rat model

(2016) Yihao Tao et al.   BRAIN BEHAVIOR AND IMMUNITY

Selective Modulator of Cannabinoid Receptor Type 2 Reduces Memory Impairment and Infarct Size During Cerebral Hypoperfusion and Vascular Dementia

(2016) Shalini Jayant et al.   CURRENT NEUROVASCULAR RESEARCH

Everolimus (RAD001) ameliorates vascular cognitive impairment by regulating microglial function via the mTORC1 signaling pathway

(2016) Li Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

MFG-E8 Selectively Inhibited Aβ-Induced Microglial M1 Polarization via NF-κB and PI3K-Akt Pathways

(2016) Xiaolei Shi et al.   MOLECULAR NEUROBIOLOGY

Paeoniflorin attenuates hippocampal damage in a rat model of vascular dementia

(2016) Ying Zhang et al.   Experimental and Therapeutic Medicine

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Paeoniflorin improves regional cerebral blood flow and suppresses inflammatory factors in the hippocampus of rats with vascular dementia

(2015) Li-gong Zhang et al.   Chinese Journal of Integrative Medicine

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis

(2015) Guohua Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trans-Caryophyllene Suppresses Hypoxia-Induced Neuroinflammatory Responses by Inhibiting NF-κB Activation in Microglia

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Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Regional Cerebral Blood Flow and Cerebrovascular Reactivity in Alzheimer's Disease and Vascular Dementia Assessed by Arterial Spinlabeling Magnetic Resonance Imaging

(2013) Yong-Zhe Gao et al.   CURRENT NEUROVASCULAR RESEARCH

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Resveratrol Inhibits Inflammatory Responses via the Mammalian Target of Rapamycin Signaling Pathway in Cultured LPS-Stimulated Microglial Cells

(2012) Lian-Mei Zhong et al.   PLoS One

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation

Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway

(2011) Leonid Tarassishin et al.   Journal of Neuroinflammation

CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity

(2011) Emmanuel S Onaivi et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Suppressive Effects of Intrathecal Paeoniflorin on Bee Venom-Induced Pain-Related Behaviors and Spinal Neuronal Activation

(2011) Hou-You Yu et al.   PHARMACOLOGY

Minocycline reduces astrocytic reactivation and neuroinflammation in the hippocampus of a vascular cognitive impairment rat model

(2010) Zhi-You Cai et al.   Neuroscience Bulletin

Anandamide enhances IL-10 production in activated microglia by targeting CB2receptors: Roles of ERK1/2, JNK, and NF-κB

(2009) Fernando Correa et al.   GLIA

Selective CB2 Receptor Agonism Protects Central Neurons from Remote Axotomy-Induced Apoptosis through the PI3K/Akt Pathway

(2009) M. T. Viscomi et al.   JOURNAL OF NEUROSCIENCE

Treatment of Vascular Dementia: The Route of Prevention

(2008) G. Sorrentino et al.   EUROPEAN NEUROLOGY

CB2receptors in the brain: role in central immune function

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