Aryl Hydrocarbon Receptor: A New Player of Pathogenesis and Therapy in Cardiovascular Diseases

ITE inhibits growth of human pulmonary artery endothelial cells

(2017) Ling-pin Pang et al.   EXPERIMENTAL LUNG RESEARCH

Coronary Artery Disease and Type 2 Diabetes Mellitus

(2017) Ryo Naito et al.   International Heart Journal

Ischemia/Reperfusion Injury following Acute Myocardial Infarction: A Critical Issue for Clinicians and Forensic Pathologists

(2017) Margherita Neri et al.   MEDIATORS OF INFLAMMATION

A comprehensive contribution of genes for aryl hydrocarbon receptor signaling pathway to hypertension susceptibility

(2017) Alexey V. Polonikov et al.   Pharmacogenetics and Genomics

Aryl hydrocarbon receptor (AHR): “pioneer member” of the basic-helix/loop/helix per - Arnt - sim (bHLH/PAS) family of “sensors” of foreign and endogenous signals

(2017) Daniel W. Nebert   PROGRESS IN LIPID RESEARCH

CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy

(2017) Xiaohui Zhang et al.   Science China-Life Sciences

Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation

(2017) Kathrin Wiebke Schulte et al.   STRUCTURE

Dual character of flavonoids in attenuating and aggravating ischemia-reperfusion-induced myocardial injury

(2017) Wenqiang Li et al.   Experimental and Therapeutic Medicine

TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells

(2017) Juyong Brian Kim et al.   PLoS Genetics

Aromatic Hydrocarbon Receptor Suppresses Prostate Cancer Bone Metastasis Cells-Induced Vasculogenesis of Endothelial Progenitor Cells under Hypoxia

(2016) Shuai Huang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Myocarditis

(2016) Gabriel Fung et al.   CIRCULATION RESEARCH

Viral myocarditis

(2016) Noel R. Rose   CURRENT OPINION IN RHEUMATOLOGY

The Aryl Hydrocarbon Receptor Modulates Production of Cytokines and Reactive Oxygen Species and Development of Myocarditis during Trypanosoma cruzi Infection

(2016) Andréia Barroso et al.   INFECTION AND IMMUNITY

Suppression of the expression of hypoxia-inducible factor-1α by RNA interference alleviates hypoxia-induced pulmonary hypertension in adult rats

(2016) Ying Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

3-Methylcholanthrene/Aryl-Hydrocarbon Receptor-Mediated Hypertension Through eNOS Inactivation

(2016) Chih-Cheng Chang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Repression of the Aryl Hydrocarbon Receptor Is Required to Maintain Mitotic Progression and Prevent Loss of Pluripotency of Embryonic Stem Cells

(2016) Chia-I Ko et al.   STEM CELLS

Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1

(2016) Benjamin J. Moyer et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Resveratrol and Cardiovascular Diseases

(2016) Dominique Bonnefont-Rousselot   Nutrients

DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical AtherosclerosisCLINICAL PERSPECTIVE

(2015) Lindsay M. Reynolds et al.   Circulation-Cardiovascular Genetics

Aryl Hydrocarbon Receptor Repressor Methylation

(2015) John W. Cole et al.   Circulation-Cardiovascular Genetics

Cross-Talk in the Female Rat Mammary Gland: Influence of Aryl Hydrocarbon Receptor on Estrogen Receptor Signaling

(2015) Janina Helle et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Current basis for discovery and development of aryl hydrocarbon receptor antagonists for experimental and therapeutic use in atherosclerosis

(2015) Larissa Pernomian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Baicalin inhibits inflammation and attenuates myocardial ischaemic injury by aryl hydrocarbon receptor

(2015) Yiqiang Xue et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Ah Receptor Activation by Dioxin Disrupts Activin, BMP, and WNT Signals During the Early Differentiation of Mouse Embryonic Stem Cells and Inhibits Cardiomyocyte Functions

(2015) Qin Wang et al.   TOXICOLOGICAL SCIENCES

2,3,7,8-Tetrachlorodibenzo-p-dioxin differentially suppresses angiogenic responses in human placental vein and artery endothelial cells

(2015) Yan Li et al.   TOXICOLOGY

Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB

(2015) Shaojie Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

AhR expression and polymorphisms are associated with risk of coronary arterial disease in Chinese population

(2015) Shian Huang et al.   Scientific Reports

DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical AtherosclerosisCLINICAL PERSPECTIVE

(2015) Lindsay M. Reynolds et al.   Circulation-Cardiovascular Genetics

Aryl Hydrocarbon Receptor Repressor Methylation

(2015) John W. Cole et al.   Circulation-Cardiovascular Genetics

L-Kynurenine/Aryl Hydrocarbon Receptor Pathway Mediates Brain Damage After Experimental Stroke

(2014) María I. Cuartero et al.   CIRCULATION

Roles of Xenobiotic Receptors in Vascular Pathophysiology

(2014) Lei Xiao et al.   CIRCULATION JOURNAL

Role of the Aryl Hydrocarbon Receptor in the Immune Response Profile and Development of Pathology during Plasmodium berghei Anka Infection

(2014) Fatima Brant et al.   INFECTION AND IMMUNITY

Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Cellular Senescence in Human Umbilical Vein Endothelial Cells

(2014) Masayuki Koizumi et al.   Journal of Atherosclerosis and Thrombosis

Baicalin attenuates transforming growth factor-β1-induced human pulmonary artery smooth muscle cell proliferation and phenotypic switch by inhibiting hypoxia inducible factor-1α and aryl hydrocarbon receptor expression

(2014) Shian Huang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Toward Understanding the Role of Aryl Hydrocarbon Receptor in the Immune System: Current Progress and Future Trends

(2014) Hamza Hanieh   Biomed Research International

The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90

(2014) Noriko Tsuji et al.   FEBS Open Bio

The emerging roles of AhR in physiology and immunity

(2013) Nan Hao et al.   BIOCHEMICAL PHARMACOLOGY

Disruption of Aryl Hydrocarbon Receptor Homeostatic Levels during Embryonic Stem Cell Differentiation Alters Expression of Homeobox Transcription Factors that Control Cardiomyogenesis

(2013) Qin Wang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Air Pollution and Incidence of Hypertension and Diabetes Mellitus in Black Women Living in Los Angeles

(2012) Patricia F. Coogan et al.   CIRCULATION

Activation of Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells

(2012) Ippei Watanabe et al.   CIRCULATION JOURNAL

Reperfusion-triggered stress protein response in the myocardium is blocked by post-conditioning. Systems biology pathway analysis highlights the key role of the canonical aryl-hydrocarbon receptor pathway

(2012) Gemma Vilahur et al.   EUROPEAN HEART JOURNAL

The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response

(2012) Francisco J. Quintana   IMMUNOLOGY

Deletion of the Aryl Hydrocarbon Receptor Enhances the Inflammatory Response to Leishmania major Infection

(2012) Guillermo Elizondo et al.   International Journal of Biological Sciences

Novel Cellular Targets of AhR Underlie Alterations in Neutrophilic Inflammation and Inducible Nitric Oxide Synthase Expression during Influenza Virus Infection

(2012) J. L. H. Wheeler et al.   JOURNAL OF IMMUNOLOGY

ShRNA-mediated gene silencing of AHR promotes the differentiation of P19 mouse embryonic carcinoma cells into cardiomyocytes

(2012) CHUN ZHU et al.   Molecular Medicine Reports

Another Important Biological Function for the Aryl Hydrocarbon Receptor

(2011) David H. Sherr   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of Aryl Hydrocarbon Receptor Induces Vascular Inflammation and Promotes Atherosclerosis in Apolipoprotein E−/− Mice

(2011) Dalei Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial cell-specific aryl hydrocarbon receptor knockout mice exhibit hypotension mediated, in part, by an attenuated angiotensin II responsiveness

(2011) Larry N. Agbor et al.   BIOCHEMICAL PHARMACOLOGY

Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art

(2011) Lucie Stejskalova et al.   CURRENT DRUG METABOLISM

Coordinate Regulation of Cytochrome P450 1A1 Expression in Mouse Liver by the Aryl Hydrocarbon Receptor and the β-Catenin Pathway

(2011) Albert Braeuning et al.   TOXICOLOGICAL SCIENCES

The Interplay of the Aryl Hydrocarbon Receptor and β-Catenin Alters Both AhR-Dependent Transcription and Wnt/β-Catenin Signaling in Liver Progenitors

(2011) Jiřina Procházková et al.   TOXICOLOGICAL SCIENCES

Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

(2011) Michael S. Denison et al.   TOXICOLOGICAL SCIENCES

Indoxyl Sulfate Upregulates Expression of ICAM-1 and MCP-1 by Oxidative Stress-Induced NF-ĸB Activation

(2010) Zohra Tumur et al.   AMERICAN JOURNAL OF NEPHROLOGY

An activated renin–angiotensin system maintains normal blood pressure in aryl hydrocarbon receptor heterozygous mice but not in null mice

(2010) Nan Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Indoxyl Sulfate Stimulates Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells by Inducing Oxidative Stress Through Activation of the NADPH Oxidase-Nuclear Factor-κB Pathway

(2010) Natsumi Masai et al.   CIRCULATION JOURNAL

Transcriptional Factor Aryl Hydrocarbon Receptor (Ahr) Controls Cardiovascular and Respiratory Functions by Regulating the Expression of theVav3Proto-oncogene

(2010) Vincent Sauzeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Unexpected Role for the Aryl Hydrocarbon Receptor on Susceptibility to Experimental Toxoplasmosis

(2010) Yuriko Sanchez et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Expression of Aryl Hydrocarbon Receptor in Human Placentas and Fetal Tissues

(2010) Yi-zhou Jiang et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Long-term air pollution exposure and risk factors for cardiovascular diseases among the elderly in Taiwan

(2010) K.-J. Chuang et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

2,3,7,8-Tetrachlorodibenzo-p-dioxin increases reactive oxygen species production in human endothelial cells via induction of cytochrome P4501A1

(2010) P.G. Kopf et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

(2009) Akihiro Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent

(2009) Zuzana Majkova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The aryl hydrocarbon receptor in immunity

(2009) Charlotte Esser et al.   TRENDS IN IMMUNOLOGY

Cellular Senescence, Cardiovascular Risk, and CKD: A Review of Established and Hypothetical Interconnections

(2008) George Tsirpanlis   AMERICAN JOURNAL OF KIDNEY DISEASES

The role of the aryl hydrocarbon receptor in the female reproductive system

(2008) Isabel Hernández-Ochoa et al.   BIOCHEMICAL PHARMACOLOGY

The aryl hydrocarbon receptor (AhR) inhibits vanadate-induced vascular endothelial growth factor (VEGF) production in TRAMP prostates

(2008) Wayne A. Fritz et al.   CARCINOGENESIS

Hypertension, Cardiac Hypertrophy, and Impaired Vascular Relaxation Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin are Associated with Increased Superoxide

(2008) Phillip G. Kopf et al.   Cardiovascular Toxicology

Loss of the Aryl Hydrocarbon Receptor Induces Hypoxemia, Endothelin-1, and Systemic Hypertension at Modest Altitude

(2008) Amie K. Lund et al.   HYPERTENSION

The Aryl Hydrocarbon Receptor Binds to E2F1 and Inhibits E2F1-induced Apoptosis

(2008) Jennifer L. Marlowe et al.   MOLECULAR BIOLOGY OF THE CELL

Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

(2008) Maureen K. Bunger et al.   TOXICOLOGICAL SCIENCES

Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway

(2008) Elizabeth Oesterling et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Benzo[a]pyrene induces expression of matrix metalloproteinases and cell migration and invasion of vascular smooth muscle cells

(2008) Dan Meng et al.   TOXICOLOGY LETTERS

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY