TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells
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Title
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells
Authors
Keywords
Coronary heart disease, Gene expression, Genome-wide association studies, Gene regulation, Genetic loci, Small interfering RNAs, Transcriptional control, Transcription factors
Journal
PLoS Genetics
Volume 13, Issue 5, Pages e1006750
Publisher
Public Library of Science (PLoS)
Online
2017-05-09
DOI
10.1371/journal.pgen.1006750
References
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Related references
Note: Only part of the references are listed.- Vascular Smooth Muscle Cells in Atherosclerosis
- (2016) Martin R. Bennett et al. CIRCULATION RESEARCH
- Putting the Genome in Context: Gene-Environment Interactions in Type 2 Diabetes
- (2016) Paul W. Franks et al. Current Diabetes Reports
- Mechanisms of DNA-binding specificity and functional gene regulation by transcription factors
- (2016) Ngaio C Smith et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Gene Expression Profiling Identifies Cell Proliferation and Inflammation as the Predominant Pathways Regulated by Aryl Hydrocarbon Receptor in Primary Human Fetal Lung Cells Exposed to Hyperoxia
- (2016) Binoy Shivanna et al. TOXICOLOGICAL SCIENCES
- Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1
- (2016) Benjamin J. Moyer et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci
- (2016) Clint L. Miller et al. Nature Communications
- Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor
- (2016) Olga Brandstätter et al. Scientific Reports
- ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability
- (2015) J. Magne et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A novel prostate cancer therapeutic strategy using icaritin-activated arylhydrocarbon-receptor to co-target androgen receptor and its splice variants
- (2015) Feng Sun et al. CARCINOGENESIS
- Gene expression signatures, pathways and networks in carotid atherosclerosis
- (2015) L. Perisic et al. JOURNAL OF INTERNAL MEDICINE
- A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
- (2015) Majid Nikpay et al. NATURE GENETICS
- Ah Receptor Signaling Controls the Expression of Cardiac Development and Homeostasis Genes
- (2015) Vinicius S. Carreira et al. TOXICOLOGICAL SCIENCES
- AhR expression and polymorphisms are associated with risk of coronary arterial disease in Chinese population
- (2015) Shian Huang et al. Scientific Reports
- Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
- (2015) Sylvia T. Nurnberg et al. PLoS Genetics
- Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci
- (2015) Olga Sazonova et al. PLoS Genetics
- Disruption of Ah Receptor Signaling during Mouse Development Leads to Abnormal Cardiac Structure and Function in the Adult
- (2015) Vinicius S. Carreira et al. PLoS One
- Aryl hydrocarbon receptor (AhR) agonists increase airway epithelial matrix metalloproteinase activity
- (2014) Ming-Ju Tsai et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A
- (2014) Khelifa Arab et al. MOLECULAR CELL
- Full-length RNA-seq from single cells using Smart-seq2
- (2014) Simone Picelli et al. Nature Protocols
- GeneFriends: a human RNA-seq-based gene and transcript co-expression database
- (2014) Sipko van Dam et al. NUCLEIC ACIDS RESEARCH
- Genetic Variants Associated with Myocardial Infarction and the Risk Factors in Chinese Population
- (2014) Yongqin Wang et al. PLoS One
- Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation
- (2014) Clint L. Miller et al. PLoS Genetics
- Nuclear Factor I genomic binding associates with chromatin boundaries
- (2013) Milos Pjanic et al. BMC GENOMICS
- Role of the aryl hydrocarbon receptor in tobacco smoke extract-induced matrix metalloproteinase-1 expression
- (2013) Yuko Ono et al. EXPERIMENTAL DERMATOLOGY
- Cross-talk between Aryl Hydrocarbon Receptor and the Inflammatory Response
- (2013) Christoph F. A. Vogel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics
- (2013) Rui M M Branca et al. NATURE METHODS
- The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
- (2013) Danielle Welter et al. NUCLEIC ACIDS RESEARCH
- Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus
- (2013) Clint L. Miller et al. PLoS Genetics
- The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression
- (2012) Timothy V. Beischlag et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart
- (2012) Caitlin M. Braitsch et al. DEVELOPMENTAL BIOLOGY
- Inflammatory Pathway Genes Belong to Major Targets of Persistent Organic Pollutants in Adipose Cells
- (2012) Min Ji Kim et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Large-scale association analysis identifies new risk loci for coronary artery disease
- (2012) Panos Deloukas et al. NATURE GENETICS
- The mystery of missing heritability: Genetic interactions create phantom heritability
- (2012) O. Zuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-Resolution Genome-wide Mapping of AHR and ARNT Binding Sites by ChIP-Seq
- (2012) Raymond Lo et al. TOXICOLOGICAL SCIENCES
- Dioxin Inhibits Zebrafish Epicardium and Proepicardium Development
- (2012) Jessica Plavicki et al. TOXICOLOGICAL SCIENCES
- Inherent and Benzo[a]pyrene-Induced Differential Aryl Hydrocarbon Receptor Signaling Greatly Affects Life Span, Atherosclerosis, Cardiac Gene Expression, and Body and Heart Growth in Mice
- (2012) Joanna S. Kerley-Hamilton et al. TOXICOLOGICAL SCIENCES
- Controls of Nucleosome Positioning in the Human Genome
- (2012) Daniel J. Gaffney et al. PLoS Genetics
- Activation of Aryl Hydrocarbon Receptor Induces Vascular Inflammation and Promotes Atherosclerosis in Apolipoprotein E−/− Mice
- (2011) Dalei Wu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Nuclear factor I revealed as family of promoter binding transcription activators
- (2011) Milos Pjanic et al. BMC GENOMICS
- Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma
- (2011) Khelifa Arab et al. CARCINOGENESIS
- Interactions of the Aryl Hydrocarbon Receptor with Inflammatory Mediators:Beyond CYP1A Regulation
- (2011) Jan Vondracek et al. CURRENT DRUG METABOLISM
- Retinoic Acid Drives Aryl Hydrocarbon Receptor Expression and Is Instrumental to Dioxin-Induced Toxicity during Palate Development
- (2011) Hugues Jacobs et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
- (2011) John F Peden et al. NATURE GENETICS
- External influences on the immune system via activation of the aryl hydrocarbon receptor
- (2011) Brigitta Stockinger et al. SEMINARS IN IMMUNOLOGY
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- Gene ontology analysis for RNA-seq: accounting for selection bias
- (2010) Matthew D Young et al. GENOME BIOLOGY
- Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA
- (2009) T. Sekiya et al. GENES & DEVELOPMENT
- Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells
- (2008) B. D. Hollingshead et al. CANCER RESEARCH
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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