Of genes and microbes: solving the intricacies in host genomes

Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition

(2018) Louise Thingholm et al.   GUT

Age, sex, and TNF associated differences in the gut microbiota of mice and their impact on acute TNBS colitis

(2017) Ariangela J. Kozik et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

NOD2 and bacterial recognition as therapeutic targets for Crohn’s disease

(2017) Magali de Bruyn et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Confounding effects of microbiome on the susceptibility of TNFSF15 to Crohn’s disease in the Ryukyu Islands

(2017) Shigeki Nakagome et al.   HUMAN GENETICS

TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice

(2017) Tunay Kökten et al.   Journal of Crohns & Colitis

Can Plant Microbiome Studies Lead to Effective Biocontrol of Plant Diseases?

(2017) Jeffrey G. Ellis   MOLECULAR PLANT-MICROBE INTERACTIONS

Alcoholic liver disease: Gut–liver axis: PPIs, Enterococcus and promotion of alcoholic liver disease

(2017) Katrina Ray   Nature Reviews Gastroenterology & Hepatology

Human genetic variation and the gut microbiome in disease

(2017) Andrew Brantley Hall et al.   NATURE REVIEWS GENETICS

Relationships between gastrointestinal microbiota and blood group antigens

(2017) Anuhya Gampa et al.   PHYSIOLOGICAL GENOMICS

Host Genetics and Gut Microbiome: Challenges and Perspectives

(2017) Alexander Kurilshikov et al.   TRENDS IN IMMUNOLOGY

Multigenerational Influences of the Fut2 Gene on the Dynamics of the Gut Microbiota in Mice

(2017) Philipp Rausch et al.   Frontiers in Microbiology

Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts

(2017) Meriem Belheouane et al.   Microbiome

Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction

(2017) Ivan Rodriguez-Nunez et al.   Scientific Reports

Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility

(2016) Marc A. Ward et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations

(2016) Alexander R. Moschen et al.   Cell Host & Microbe

Genetic Determinants of the Gut Microbiome in UK Twins

(2016) Julia K. Goodrich et al.   Cell Host & Microbe

A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition

(2016) Dalin Li et al.   GASTROENTEROLOGY

Infectious disease: Something in the water

(2016) Sujata Gupta   NATURE

The gut microbiome—an emerging complex trait

(2016) Andrew K Benson   NATURE GENETICS

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

(2016) Jun Wang et al.   NATURE GENETICS

The effect of host genetics on the gut microbiome

(2016) Marc Jan Bonder et al.   NATURE GENETICS

Association of host genome with intestinal microbial composition in a large healthy cohort

(2016) Williams Turpin et al.   NATURE GENETICS

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Epithelial calcineurin controls microbiota-dependent intestinal tumor development

(2016) Kenneth Peuker et al.   NATURE MEDICINE

Emerging pathogenic links between microbiota and the gut–lung axis

(2016) Kurtis F. Budden et al.   NATURE REVIEWS MICROBIOLOGY

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

(2016) Moran Yassour et al.   Science Translational Medicine

FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis

(2016) Steven L Taylor et al.   THORAX

Role ofHelicobacter pyloriand interleukin 6 -174 gene polymorphism in dyslipidemia: a case–control study

(2016) Vesa-Matti Pohjanen et al.   BMJ Open

Middle ear microbiome differences in indigenous Filipinos with chronic otitis media due to a duplication in the A2ML1 gene

(2016) Regie Lyn P. Santos-Cortez et al.   Infectious Diseases of Poverty

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome

(2016) Hailiang Xie et al.   Cell Systems

Host Genetic Control of the Microbiota Mediates the Drosophila Nutritional Phenotype

(2015) John M. Chaston et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

(2015) Aleksandar D. Kostic et al.   Cell Host & Microbe

Lack of Vitamin D Receptor Causes Dysbiosis and Changes the Functions of the Murine Intestinal Microbiome

(2015) Dapeng Jin et al.   CLINICAL THERAPEUTICS

Genetic and environmental control of host-gut microbiota interactions

(2015) Elin Org et al.   GENOME RESEARCH

IL-22-STAT3 Pathway Plays a Key Role in the Maintenance of Ileal Homeostasis in Mice Lacking Secreted Mucus Barrier

(2015) Bruno Sovran et al.   INFLAMMATORY BOWEL DISEASES

MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection

(2015) Jason L. Kubinak et al.   Nature Communications

Analysis of intestinal microbiota in hybrid house mice reveals evolutionary divergence in a vertebrate hologenome

(2015) Jun Wang et al.   Nature Communications

Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster

(2015) Adam J. Dobson et al.   Nature Communications

Host Biology in Light of the Microbiome: Ten Principles of Holobionts and Hologenomes

(2015) Seth R. Bordenstein et al.   PLOS BIOLOGY

Expression of the Blood-Group-Related Gene B4galnt2 Alters Susceptibility to Salmonella Infection

(2015) Philipp Rausch et al.   PLoS Pathogens

The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease

(2015) Robert P. Dickson et al.   PLoS Pathogens

Agrobacterium: nature’s genetic engineer

(2015) Eugene W. Nester   Frontiers in Plant Science

Sex, Body Mass Index, and Dietary Fiber Intake Influence the Human Gut Microbiome

(2015) Christine Dominianni et al.   PLoS One

The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study

(2015) Johannes R. Hov et al.   PLoS One

Genome-Wide Association Studies of the Human Gut Microbiota

(2015) Emily R. Davenport et al.   PLoS One

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

(2014) Markus Tschurtschenthaler et al.   GUT

TheATG16L1–T300Aallele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients

(2014) Mehdi Sadaghian Sadabad et al.   GUT

Copy Number Variation of the Beta Defensin Gene Cluster on Chromosome 8p Influences the Bacterial Microbiota within the Nasopharynx of Otitis-Prone Children

(2014) Eric A. Jones et al.   PLoS One

Additive Effect between IL-13 Polymorphism and Cesarean Section Delivery/Prenatal Antibiotics Use on Atopic Dermatitis: A Birth Cohort Study (COCOA)

(2014) So-Yeon Lee et al.   PLoS One

Loss of Sirt1 Function Improves Intestinal Anti-Bacterial Defense and Protects from Colitis-Induced Colorectal Cancer

(2014) Giuseppe Lo Sasso et al.   PLoS One

Rapid changes in the gut microbiome during human evolution

(2014) Andrew H. Moeller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Genome Evolution Between Companion Symbionts in an Insect-Bacterial Symbiosis

(2014) G. M. Bennett et al.   mBio

Genome-wide association study of Arabidopsis thaliana leaf microbial community

(2014) Matthew W. Horton et al.   Nature Communications

Tipping elements in the human intestinal ecosystem

(2014) Leo Lahti et al.   Nature Communications

Human Evolution: New Playgrounds for Natural Selection

(2013) Emmanuel Milot et al.   CURRENT BIOLOGY

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

The Hologenomic Basis of Speciation: Gut Bacteria Cause Hybrid Lethality in the Genus Nasonia

(2013) R. M. Brucker et al.   SCIENCE

Genome-wide mapping of gene–microbiota interactions in susceptibility to autoimmune skin blistering

(2013) Girish Srinivas et al.   Nature Communications

Quantitative Genetic Background of the Host Influences Gut Microbiomes in Chickens

(2013) Lele Zhao et al.   Scientific Reports

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

Expression of the blood-group-related glycosyltransferase B4galnt2 influences the intestinal microbiota in mice

(2012) Fabian Staubach et al.   ISME Journal

Defining the core Arabidopsis thaliana root microbiome

(2012) Derek S. Lundberg et al.   NATURE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Human population structure and the adaptive response to pathogen-induced selection pressures

(2012) J. Novembre et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits

(2012) Autumn M. McKnite et al.   PLoS One

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Pathway analysis of genomic data: concepts, methods, and prospects for future development

(2012) Vijay K. Ramanan et al.   TRENDS IN GENETICS

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

(2012) Xochitl C Morgan et al.   GENOME BIOLOGY

Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88

(2011) Erik Larsson et al.   GUT

Mutations in the ELANE Gene are Associated with Development of Periodontitis in Patients with Severe Congenital Neutropenia

(2011) Ying Ye et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Human nutrition, the gut microbiome and the immune system

(2011) Andrew L. Kau et al.   NATURE

The skin microbiome

(2011) Elizabeth A. Grice et al.   NATURE REVIEWS MICROBIOLOGY

Unravelling the effects of the environment and host genotype on the gut microbiome

(2011) Aymé Spor et al.   NATURE REVIEWS MICROBIOLOGY

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

(2011) P. Rausch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Gut Microbiome: Ecology and Recent Evolutionary Changes

(2010) Jens Walter et al.   Annual Review of Microbiology

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

(2010) Dermot P.B. McGovern et al.   HUMAN MOLECULAR GENETICS

UniFrac: an effective distance metric for microbial community comparison

(2010) Catherine Lozupone et al.   ISME Journal

The Human Oral Microbiome

(2010) F. E. Dewhirst et al.   JOURNAL OF BACTERIOLOGY

Clinical Periodontal and Microbiologic Parameters in Patients With Crohn's Disease With Consideration of the CARD15 Genotype

(2010) Jamal M. Stein et al.   JOURNAL OF PERIODONTOLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

New approaches to population stratification in genome-wide association studies

(2010) Alkes L. Price et al.   NATURE REVIEWS GENETICS

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

(2010) A. K. Benson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaginal microbiome of reproductive-age women

(2010) J. Ravel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary Relationships of Wild Hominids Recapitulated by Gut Microbial Communities

(2010) Howard Ochman et al.   PLOS BIOLOGY

Human gut microbiome: the second genome of human body

(2010) Baoli Zhu et al.   Protein & Cell

From evolutionary genetics to human immunology: how selection shapes host defence genes

(2009) Luis B. Barreiro et al.   NATURE REVIEWS GENETICS

Efficient Control of Population Structure in Model Organism Association Mapping

(2008) H. M. Kang et al.   GENETICS

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

Natural selection has driven population differentiation in modern humans

(2008) Luis B Barreiro et al.   NATURE GENETICS

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS

Worlds within worlds: evolution of the vertebrate gut microbiota

(2008) Ruth E. Ley et al.   NATURE REVIEWS MICROBIOLOGY