Thiolated Hyaluronic Acid as Versatile Mucoadhesive Polymer: From the Chemistry Behind to Product Developments—What Are the Capabilities?

Surface modification of model hydrogel contact lenses with hyaluronic acid via thiol-ene “click” chemistry for enhancing surface characteristics

(2017) Myrto Korogiannaki et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

A Review of Hyaluronic Acid and Hyaluronic Acid-based Hydrogels for Vocal Fold Tissue Engineering

(2017) Tanaya Walimbe et al.   JOURNAL OF VOICE

Efficacy of two different thiol-modified crosslinked hyaluronate formulations as vitreous replacement compared to silicone oil in a model of retinal detachment

(2017) Sven Schnichels et al.   PLoS One

In Vitro and Ex Vivo Evaluation of Novel Curcumin-Loaded Excipient for Buccal Delivery

(2016) Flavia Laffleur et al.   AAPS PHARMSCITECH

Improved scaffold biocompatibility through anti-Fibronectin aptamer functionalization

(2016) C. Galli et al.   Acta Biomaterialia

Totally S-protected hyaluronic acid: Evaluation of stability and mucoadhesive properties as liquid dosage form

(2016) Irene Pereira de Sousa et al.   CARBOHYDRATE POLYMERS

The self-crosslinking smart hyaluronic acid hydrogels as injectable three-dimensional scaffolds for cells culture

(2016) Shaoquan Bian et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Thiol-ene crosslinking polyamidoamine dendrimer-hyaluronic acid hydrogel system for biomedical applications

(2016) Xiangdong Bi et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Smart nanoparticles with a detachable outer shell for maximized synergistic antitumor efficacy of therapeutics with varying physicochemical properties

(2016) Tingjie Yin et al.   JOURNAL OF CONTROLLED RELEASE

In vivo biocompatibility of p(HPMAm-lac)-PEG hydrogels hybridized with hyaluronan

(2016) Maria Giovanna Sabbieti et al.   Journal of Tissue Engineering and Regenerative Medicine

Biocompatibility of a Self-Assembled Crosslinkable Hyaluronic Acid Nanogel

(2016) Sílvia Santos Pedrosa et al.   MACROMOLECULAR BIOSCIENCE

Stimuli-sensitive thiolated hyaluronic acid based nanofibers: synthesis, preclinical safety and in vitro anti-HIV activity

(2016) Vivek Agrahari et al.   Nanomedicine

Strategies to Prolong the Intravaginal Residence Time of Drug Delivery Systems

(2016) Esra Baloglu et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Evaluation of functional characteristics of preactivated thiolated chitosan as potential therapeutic agent for dry mouth syndrome

(2015) Flavia Laffleur et al.   Acta Biomaterialia

Nanofibrous Hydrogels with Spatially Patterned Biochemical Signals to Control Cell Behavior

(2015) Ryan J. Wade et al.   ADVANCED MATERIALS

Hyperbranched phosphoramidate-hyaluronan hybrid: A reduction-sensitive injectable hydrogel for controlled protein release

(2015) Yuhong Liu et al.   CARBOHYDRATE POLYMERS

Conjugating an anticancer drug onto thiolated hyaluronic acid by acid liable hydrazone linkage for its gelation and dual stimuli-response release

(2015) Chaoping Fu et al.   CARBOHYDRATE POLYMERS

Optimal design for studying mucoadhesive polymers interaction with gastric mucin using a quartz crystal microbalance with dissipation (QCM-D): Comparison of two different mucin origins

(2015) Sejin Oh et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Injectable hyaluronic acid/PEG-p(HPMAm-lac)-based hydrogels dually cross-linked by thermal gelling and Michael addition

(2015) Alessandra Dubbini et al.   EUROPEAN POLYMER JOURNAL

A potential tailor-made hyaluronic acid buccal delivery system comprising rotigotine for Parkinson's disease?

(2015) Flavia Laffleur et al.   Future Medicinal Chemistry

In vitro and ex vivo evaluation of biomaterials' distinctive properties as a result of thiolation

(2015) Flavia Laffleur et al.   Future Medicinal Chemistry

Preactivated hyaluronic acid: A potential mucoadhesive polymer for vaginal delivery

(2015) Jessika Nowak et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Bioreducible core-crosslinked hyaluronic acid micelle for targeted cancer therapy

(2015) Hwa Seung Han et al.   JOURNAL OF CONTROLLED RELEASE

Cationic liposome–hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens

(2015) Yuchen Fan et al.   JOURNAL OF CONTROLLED RELEASE

Controlled release of a model protein drug ovalbumin from thiolated hyaluronic acid matrix

(2015) Jinping Du et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Permeation Enhancement via Thiolation: In Vitro and Ex Vivo Evaluation of Hyaluronic Acid-Cysteine Ethyl Ester

(2015) Flavia Laffleur et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effect of Immobilized Thiolated Glycosaminoglycans on Fibronectin Adsorption and Behavior of Fibroblasts

(2015) Alexander Köwitsch et al.   MACROMOLECULAR BIOSCIENCE

Injectable Chemically Crosslinked Hydrogel for the Controlled Release of Bevacizumab in Vitreous: A 6-Month In Vivo Study

(2015) Yu Yu et al.   Translational Vision Science & Technology

Formulation of In Situ Chemically Cross-Linked Hydrogel Depots for Protein Release: From the Blob Model Perspective

(2014) Yu Yu et al.   BIOMACROMOLECULES

Chemical Modification of Hyaluronic Acid for Intraoral Application

(2014) Flavia Laffleur et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Efficacy of a Crosslinked Hyaluronic Acid-Based Hydrogel as a Tear Film Supplement: A Masked Controlled Study

(2014) David L. Williams et al.   PLoS One

Ophthalmic Uses of a Thiol-Modified Hyaluronan-Based Hydrogel

(2014) Barbara Wirostko et al.   Advances in Wound Care

Thiolated hyaluronan-based hydrogels crosslinked using oxidized glutathione: An injectable matrix designed for ophthalmic applications

(2013) Thomas I. Zarembinski et al.   Acta Biomaterialia

Preactivated thiomers for vaginal drug delivery vehicles

(2013) Heike E. Friedl et al.   BIOMATERIALS

Development andin vitroevaluation of a buccal drug delivery system based on preactivated thiolated pectin

(2013) Sabine Hauptstein et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Design and in vitro evaluation of a novel polymeric excipient for buccal applications

(2013) Flavia Laffleur et al.   Future Medicinal Chemistry

Encapsulation and 3D culture of human adipose-derived stem cells in an in-situ crosslinked hybrid hydrogel composed of PEG-based hyperbranched copolymer and hyaluronic acid

(2013) Waqar Hassan et al.   Stem Cell Research & Therapy

The translational imperative: Making cell therapy simple and effective

(2012) Glenn D. Prestwich et al.   Acta Biomaterialia

Multilayered mucoadhesive hydrogel films based on thiolated hyaluronic acid and polyvinylalcohol for insulin delivery

(2012) J. Ding et al.   Acta Biomaterialia

Adipose-Derived Stem Cells on Hyaluronic Acid–Derived Scaffold

(2012) Ladan Espandar   ARCHIVES OF OPHTHALMOLOGY

Chitosan-based drug delivery systems

(2012) Andreas Bernkop-Schnürch et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The Application of Hyaluronic Acid Hydrogels to Retinal Progenitor Cell Transplantation

(2012) Yong Liu et al.   TISSUE ENGINEERING PART A

Hyaluronic Acid Hydrogels for Biomedical Applications

(2011) Jason A. Burdick et al.   ADVANCED MATERIALS

Network connectivity, mechanical properties and cell adhesion for hyaluronic acid/PEG hydrogels

(2011) Sihem Ouasti et al.   BIOMATERIALS

Preactivated thiomers as mucoadhesive polymers for drug delivery

(2011) Javed Iqbal et al.   BIOMATERIALS

Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications

(2011) Carole E. Schanté et al.   CARBOHYDRATE POLYMERS

In Vitro Evaluation of Mucoadhesive Vaginal Tablets of Antifungal Drugs Prepared with Thiolated Polymer and Development of a New Dissolution Technique for Vaginal Formulations

(2011) Esra Baloglu et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine

(2011) Glenn D. Prestwich   JOURNAL OF CONTROLLED RELEASE

Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates

(2010) Aleksander Skardal et al.   BIOMATERIALS

Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro

(2010) Jennifer L. Young et al.   BIOMATERIALS

In Vivo Engineering of the Vocal Fold ECM With Injectable HA Hydrogels—Late Effects on Tissue Repair and Biomechanics in a Rabbit Model

(2010) Susan L. Thibeault et al.   JOURNAL OF VOICE

In Situ Forming Hydrogels by Tandem Thermal Gelling and Michael Addition Reaction between Thermosensitive Triblock Copolymers and Thiolated Hyaluronan

(2010) Roberta Censi et al.   MACROMOLECULES

Structural, mechanical and osmotic properties of injectable hyaluronan-based composite hydrogels

(2010) Ferenc Horkay et al.   POLYMER

A cross-linked hyaluronan gel accelerates healing of corneal epithelial abrasion and alkali burn injuries in rabbits

(2010) Guanghui Yang et al.   VETERINARY OPHTHALMOLOGY

Characterization of polyelectrolyte features in polysaccharide systems and mucin

(2009) Bo Nyström et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Biological effects of hyaluronan in connective tissues, eye, skin, venous wall. Role in aging

(2009) L. Robert et al.   PATHOLOGIE BIOLOGIE

Synthesis, characterization and chondroprotective properties of a hyaluronan thioethyl ether derivative

(2008) Monica A. Serban et al.   BIOMATERIALS

Development and In Vitro Evaluation of a Mucoadhesive Vaginal Delivery System for Nystatin

(2008) Juliane Hombach et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Rheological Properties of Cross-Linked Hyaluronan-Gelatin Hydrogels for Tissue Engineering

(2008) Janssen L. Vanderhooft et al.   MACROMOLECULAR BIOSCIENCE