DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity

PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization

(2017) Pak-Yin Lui et al.   JOURNAL OF IMMUNOLOGY

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

(2017) Peng Tan et al.   MOLECULAR CELL

Optical control of membrane tethering and interorganellar communication at nanoscales

(2017) Lian He et al.   Chemical Science

Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality

(2016) Xiao Yu et al.   IMMUNITY

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity

(2016) Xueting Lang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

USP38 Inhibits Type I Interferon Signaling by Editing TBK1 Ubiquitination through NLRP4 Signalosome

(2016) Meng Lin et al.   MOLECULAR CELL

TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses

(2016) Meixin Chen et al.   MOLECULAR CELL

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

(2014) Safia Deddouche et al.   eLife

Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29

(2013) Yaser Hashem et al.   CELL

USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors

(2013) Jun Cui et al.   CELL RESEARCH

Dephosphorylation of the RNA Sensors RIG-I and MDA5 by the Phosphatase PP1 Is Essential for Innate Immune Signaling

(2013) Effi Wies et al.   IMMUNITY

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Paramyxovirus V Proteins Disrupt the Fold of the RNA Sensor MDA5 to Inhibit Antiviral Signaling

(2013) C. Motz et al.   SCIENCE

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5

(2012) Bin Wu et al.   CELL

The RIG-I-like Receptor LGP2 Controls CD8+ T Cell Survival and Fitness

(2012) Mehul S. Suthar et al.   IMMUNITY

Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response

(2012) Xiaomo Jiang et al.   IMMUNITY

LGP2 Downregulates Interferon Production during Infection with Seasonal Human Influenza A Viruses That Activate Interferon Regulatory Factor 3

(2012) M. Malur et al.   JOURNAL OF VIROLOGY

Paramyxovirus V Proteins Interact with the RNA Helicase LGP2 To Inhibit RIG-I-Dependent Interferon Induction

(2012) K. Childs et al.   JOURNAL OF VIROLOGY

NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4

(2012) Jun Cui et al.   NATURE IMMUNOLOGY

Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs

(2012) V. Dhote et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments

(2012) A. Peisley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into RNA Recognition by RIG-I

(2011) Dahai Luo et al.   CELL

The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES

(2011) Yingpu Yu et al.   EMBO JOURNAL

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells

(2011) Zhiqiang Zhang et al.   IMMUNITY

RIG-I-like receptors: cytoplasmic sensors for non-self RNA

(2011) Hiroki Kato et al.   IMMUNOLOGICAL REVIEWS

Conventional Protein Kinase C-  (PKC- ) and PKC-  Negatively Regulate RIG-I Antiviral Signal Transduction

(2011) N. P. Maharaj et al.   JOURNAL OF VIROLOGY

A Distinct Class of Internal Ribosomal Entry Site in Members of the Kobuvirus and Proposed Salivirus and Paraturdivirus Genera of the Picornaviridae

(2011) T. R. Sweeney et al.   JOURNAL OF VIROLOGY

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

(2011) Fuguo Jiang et al.   NATURE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

(2011) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

mRNA helicases: the tacticians of translational control

(2011) Armen Parsyan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA helicases

(2011) Arnaz Ranji et al.   RNA Biology

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

The Inflammasomes

(2010) Kate Schroder et al.   CELL

NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways

(2010) Jun Cui et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Bypassing of stems versus linear base-by-base inspection of mammalian mRNAs during ribosomal scanning

(2010) Irina S Abaeva et al.   EMBO JOURNAL

Phosphorylation-Mediated Negative Regulation of RIG-I Antiviral Activity

(2010) M. U. Gack et al.   JOURNAL OF VIROLOGY

LGP2: Positive about viral sensing

(2010) E. M. Y. Moresco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

(2010) T. Satoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How the Noninflammasome NLRs Function in the Innate Immune System

(2010) J. P. Y. Ting et al.   SCIENCE

Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection

(2009) A. Pichlmair et al.   JOURNAL OF VIROLOGY

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis

(2009) Armen Parsyan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translation Initiation on Mammalian mRNAs with Structured 5′UTRs Requires DExH-Box Protein DHX29

(2008) Vera P. Pisareva et al.   CELL

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

(2008) Didier Soulat et al.   EMBO JOURNAL