Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface
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Title
Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface
Authors
Keywords
Enzyme inhibitors, Crystal structure, Adenosine, Dimerization, Enzyme structure, Library screening, Enzymes, Immune response
Journal
PLoS Computational Biology
Volume 14, Issue 1, Pages e1005943
Publisher
Public Library of Science (PLoS)
Online
2018-01-30
DOI
10.1371/journal.pcbi.1005943
References
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