Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture

The Temporal Pattern, Flux, and Function of Autophagy in Spinal Cord Injury

(2017) Kailiang Zhou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition

(2017) Iain S. Haslam et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo

(2017) Xiuzu Song et al.   Redox Biology

Systemic causes of hair loss

(2016) Richard L. Lin et al.   ANNALS OF MEDICINE

Spermidine reduces lipid accumulation and necrotic core formation in atherosclerotic plaques via induction of autophagy

(2016) Cédéric F. Michiels et al.   ATHEROSCLEROSIS

The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish

(2016) Guodong Huang et al.   Autophagy

Spermidine boosts autophagy to protect from synapse aging

(2016) Anuradha Bhukel et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair

(2016) Diana H. Liang et al.   CANCER LETTERS

A primer for studying cell cycle dynamics of the human hair follicle

(2016) Talveen S. Purba et al.   EXPERIMENTAL DERMATOLOGY

BNIP3 plays crucial roles in the differentiation and maintenance of epidermal keratinocytes

(2016) Mariko Moriyama et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

A Guide to Studying Human Hair Follicle Cycling In Vivo

(2016) Ji Won Oh et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hair follicle characteristics as early marker of Type 2 Diabetes

(2016) J. Jaime Miranda et al.   MEDICAL HYPOTHESES

mTOR-Independent autophagy inducer trehalose rescues against insulin resistance-induced myocardial contractile anomalies: Role of p38 MAPK and Foxo1

(2016) Qiurong Wang et al.   PHARMACOLOGICAL RESEARCH

Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells

(2016) Zhao Jing et al.   Oncotarget

Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice

(2015) Martina Chrisam et al.   Autophagy

Transcriptional and epigenetic regulation of autophagy in aging

(2015) Louis R Lapierre et al.   Autophagy

Modulation of inflammation by autophagy: Consequences for human disease

(2015) Romana T. Netea-Maier et al.   Autophagy

Differential expression and functionality of ATP-binding cassette transporters in the human hair follicle

(2015) I.S. Haslam et al.   BRITISH JOURNAL OF DERMATOLOGY

Autophagy in stem and progenitor cells

(2015) Carlo Rodolfo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Human hair follicle organ culture: theory, application and perspectives

(2015) Ewan A. Langan et al.   EXPERIMENTAL DERMATOLOGY

The Circadian Clock in Skin

(2015) Maksim V. Plikus et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Development of autophagy inducers in clinical medicine

(2015) Beth Levine et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy in cellular metabolism and cancer

(2015) Xuejun Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy: a druggable process that is deregulated in aging and human disease

(2015) Guido Kroemer   JOURNAL OF CLINICAL INVESTIGATION

Selective autophagy: Xenophagy

(2015) Kyle A. Bauckman et al.   METHODS

FGF signalling regulates bone growth through autophagy

(2015) Laura Cinque et al.   NATURE

Dual attenuation of proteasomal and autophagic BMAL1 degradation in ClockΔ19/+ mice contributes to improved glucose homeostasis

(2015) Kwon Jeong et al.   Scientific Reports

Caffeine promotes autophagy in skeletal muscle cells by increasing the calcium-dependent activation of AMP-activated protein kinase

(2014) T.S. Mathew et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor-β2/insulin-like growth factor-1-mediated regulation of the hair cycle in male and female human hair follicle

(2014) T.W. Fischer et al.   BRITISH JOURNAL OF DERMATOLOGY

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

(2014) F Pietrocola et al.   CELL DEATH AND DIFFERENTIATION

Dual inhibition of REV-ERBβ and autophagy as a novel pharmacological approach to induce cytotoxicity in cancer cells

(2014) C De Mei et al.   ONCOGENE

Neuroendocrinology of the hair follicle: principles and clinical perspectives

(2014) Ralf Paus et al.   TRENDS IN MOLECULAR MEDICINE

Cutting a fine figure

(2013) John Milton Lucocq et al.   Autophagy

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice

(2013) Rohit A. Sinha et al.   HEPATOLOGY

Autophagy Has a Significant Role in Determining Skin Color by Regulating Melanosome Degradation in Keratinocytes

(2013) Daiki Murase et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock

(2013) Yusur Al-Nuaimi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche

(2013) Matthew J Harries et al.   JOURNAL OF PATHOLOGY

Pathobiology of chemotherapy-induced hair loss

(2013) Ralf Paus et al.   LANCET ONCOLOGY

Expression of Ambra1 in mouse brain during physiological and Alzheimer type aging

(2013) Sara Sepe et al.   NEUROBIOLOGY OF AGING

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Autophagy and Intestinal Homeostasis

(2012) Khushbu K. Patel et al.   Annual Review of Physiology

Endocannabinoids limit excessive mast cell maturation and activation in human skin

(2012) Koji Sugawara et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

P-Cadherin Regulates Human Hair Growth and Cycling via Canonical Wnt Signaling and Transforming Growth Factor-β2

(2012) Liat Samuelov et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A prototypic mathematical model of the human hair cycle

(2012) Yusur Al-Nuaimi et al.   JOURNAL OF THEORETICAL BIOLOGY

Time-resolved chloroquine-induced relaxation of supercoiled plasmid DNA

(2011) Marek Mahut et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Temporal orchestration of circadian autophagy rhythm by C/EBPβ

(2011) Di Ma et al.   EMBO JOURNAL

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

A high content screening assay for identifying lysosomotropic compounds

(2010) Sashi Nadanaciva et al.   TOXICOLOGY IN VITRO

The Hair Follicle as a Dynamic Miniorgan

(2009) Marlon R. Schneider et al.   CURRENT BIOLOGY

Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies

(2009) V. Raja Solomon et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture

(2009) Jennifer Elisabeth Kloepper et al.   EXPERIMENTAL DERMATOLOGY

Profiling the Response of Human Hair Follicles to Ultraviolet Radiation

(2009) Zhongfa Lu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack

(2007) Taisuke Ito et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY