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Title
TREM2-Dependent Effects on Microglia in Alzheimer’s Disease
Authors
Keywords
-
Journal
Frontiers in Aging Neuroscience
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-07-09
DOI
10.3389/fnagi.2018.00202
References
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Note: Only part of the references are listed.- Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism
- (2018) Wilbur M. Song et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
- (2018) Yingjun Zhao et al. NEURON
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Soluble TREM2 induces inflammatory responses and enhances microglial survival
- (2017) Li Zhong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
- (2017) Shane M. Bemiller et al. Molecular Neurodegeneration
- Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
- (2017) Carmen Venegas et al. NATURE
- TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
- (2017) Cheryl E. G. Leyns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology
- (2016) Elizabeth E. Spangenberg et al. BRAIN
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease
- (2016) Taylor R. Jay et al. JOURNAL OF NEUROSCIENCE
- p62 improves AD-like pathology by increasing autophagy
- (2016) A Caccamo et al. MOLECULAR PSYCHIATRY
- TREM2 variants: new keys to decipher Alzheimer disease pathogenesis
- (2016) Marco Colonna et al. NATURE REVIEWS NEUROSCIENCE
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- How neuroinflammation contributes to neurodegeneration
- (2016) R. M. Ransohoff SCIENCE
- Early changes in CSF sTREM2 in dominantly inherited Alzheimers disease occur after amyloid deposition and neuronal injury
- (2016) M. Suarez-Calvet et al. Science Translational Medicine
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM-2 promotes macrophage survival and lung disease after respiratory viral infection
- (2015) Kangyun Wu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
- (2015) Taylor R. Jay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
- (2015) Carlo Condello et al. Nature Communications
- TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices
- (2014) Lih-Fen Lue et al. BRAIN PATHOLOGY
- Coding variants in TREM2 increase risk for Alzheimer's disease
- (2014) Sheng Chih Jin et al. HUMAN MOLECULAR GENETICS
- Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2
- (2014) Jason D Ulrich et al. Molecular Neurodegeneration
- Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes
- (2014) Mathias Thelen et al. NEUROBIOLOGY OF AGING
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis
- (2014) Janet Cady et al. JAMA Neurology
- Inconsistencies and Controversies Surrounding the Amyloid Hypothesis of Alzheimer's Disease
- (2014) Gary P Morris et al. Acta Neuropathologica Communications
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage
- (2013) Patrick Wunderlich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease
- (2013) Sruti Rayaprolu et al. Molecular Neurodegeneration
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer’s disease
- (2013) B Parajuli et al. Cell Death & Disease
- TREM2 and -Catenin Regulate Bone Homeostasis by Controlling the Rate of Osteoclastogenesis
- (2012) K. Otero et al. JOURNAL OF IMMUNOLOGY
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
- (2012) Yaming Wang et al. NATURE IMMUNOLOGY
- Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
- (2012) Dorothy P. Schafer et al. NEURON
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau
- (2010) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Genetics of Alzheimer Disease: Back to the Future
- (2010) Lars Bertram et al. NEURON
- Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
- (2010) Patricia Spilman et al. PLoS One
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- TREM2- and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1
- (2010) Q. Peng et al. Science Signaling
- TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria
- (2009) Elsa-Noah N'Diaye et al. JOURNAL OF CELL BIOLOGY
- Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
- (2009) Clifford R Jack et al. LANCET NEUROLOGY
- TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice
- (2008) Stefanie Frank et al. GLIA
- The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
- (2008) Fiona Pickford et al. JOURNAL OF CLINICAL INVESTIGATION
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