The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia

Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway

(2016) Yan Feng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Inflammaging: disturbed interplay between autophagy and inflammasomes

(2016) Antero Salminen et al.   Aging-US

Prion Pathogenesis in the Absence of NLRP3/ASC Inflammasomes

(2015) Mario Nuvolone et al.   PLoS One

Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3

(2014) Hiroshi Aoki et al.   Autophagy

Caspase-1 Cleavage of the TLR Adaptor TRIF Inhibits Autophagy and β-Interferon Production during Pseudomonas aeruginosa Infection

(2014) Majid Sakhi Jabir et al.   Cell Host & Microbe

Membrane trafficking and autophagy in pathogen-triggered cell death and immunity

(2014) O.-K. Teh et al.   JOURNAL OF EXPERIMENTAL BOTANY

Lipopolysaccharide Induces Inflammatory Hyperalgesia Triggering a TLR4/MyD88-Dependent Cytokine Cascade in the Mice Paw

(2014) Igor L. Calil et al.   PLoS One

Harnessing of TLR-mediated autophagy to combat mycobacteria in macrophages

(2014) Yi Xu et al.   TUBERCULOSIS

Pathogen-Induced Autophagy Signaling in Innate Immunity

(2013) Mathias Faure et al.   Journal of Innate Immunity

Inhibition of phagocytosis and lysosomal acidification suppresses neurotoxic prion peptide-induced NALP3 inflammasome activation in BV2 microglia

(2013) Fushan Shi et al.   JOURNAL OF NEUROIMMUNOLOGY

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis

(2012) Neng-Yu Lin et al.   ANNALS OF THE RHEUMATIC DISEASES

Autophagy proteins play cytoprotective and cytocidal roles in leucine starvation-induced cell death inSaccharomyces cerevisiae

(2012) Slawomir A. Dziedzic et al.   Autophagy

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

(2012) Iva Hafner-Bratkovič et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

(2012) Fushan Shi et al.   Journal of Neuroinflammation

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy: cellular defense to excessive inflammation

(2011) Eun-Kyeong Jo et al.   MICROBES AND INFECTION

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

(2011) Jacob I. Ayers et al.   PLoS Pathogens

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Control of infection by pyroptosis and autophagy: role of TLR and NLR

(2010) Karina R. Bortoluci et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation

(2010) Martina M. Hughes et al.   GLIA

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Autophagy and innate immunity: Triggering, targeting and tuning

(2010) Rhea Sumpter et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The intricate mechanisms of neurodegeneration in prion diseases

(2010) Claudio Soto et al.   TRENDS IN MOLECULAR MEDICINE

The Physical Relationship between Infectivity and Prion Protein Aggregates Is Strain-Dependent

(2010) Philippe Tixador et al.   PLoS Pathogens

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Role of microglia in neuronal degeneration and regeneration

(2009) Lisa Walter et al.   Seminars in Immunopathology

The Inflammasomes

(2009) Mohamed Lamkanfi et al.   PLoS Pathogens

Prion Proteins Leading to Neurodegeneration

(2008) D. Mendola et al.   Current Alzheimer Research

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE