Microfluidic Tumor-Vascular Model to Study Breast Cancer Cell Invasion and Intravasation

Effect of suberoylanilide hydroxamic acid (SAHA) on breast cancer cells within a tumor–stroma microfluidic model

(2017) N. Peela et al.   Integrative Biology

Cell migration in microengineered tumor environments

(2017) Eujin Um et al.   LAB ON A CHIP

Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: their emerging role in tumor heterogeneity

(2017) Odessa Schillaci et al.   Scientific Reports

A three dimensional micropatterned tumor model for breast cancer cell migration studies

(2016) Nitish Peela et al.   BIOMATERIALS

Apoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis

(2016) Emma C. Watson et al.   DEVELOPMENT

Microengineered cancer-on-a-chip platforms to study the metastatic microenvironment

(2016) R. Portillo-Lara et al.   LAB ON A CHIP

Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment

(2016) Danh Truong et al.   Scientific Reports

Recapitulation of in vivo-like paracrine signals of human mesenchymal stem cells for functional neuronal differentiation of human neural stem cells in a 3D microfluidic system

(2015) Kisuk Yang et al.   BIOMATERIALS

Multi-parametric hydrogels support 3D in vitro bioengineered microenvironment models of tumour angiogenesis

(2015) Laura J. Bray et al.   BIOMATERIALS

Co-culture of 3D tumor spheroids with fibroblasts as a model for epithelial–mesenchymal transition in vitro

(2015) Sun-Ah Kim et al.   EXPERIMENTAL CELL RESEARCH

Microfluidic 3D models of cancer

(2014) Kyung Eun Sung et al.   ADVANCED DRUG DELIVERY REVIEWS

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer

(2014) Britta Weigelt et al.   ADVANCED DRUG DELIVERY REVIEWS

Microfluidic techniques for development of 3D vascularized tissue

(2014) Anwarul Hasan et al.   BIOMATERIALS

A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation

(2014) Hyunjae Lee et al.   Biomicrofluidics

A three-dimensional in vitro model of tumor cell intravasation

(2014) Seema M. Ehsan et al.   Integrative Biology

Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

(2014) Jessie S. Jeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-associated lymphatic endothelial cell promotes invasion of cervical cancer cells

(2013) Liqiong Cai et al.   APMIS

Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis

(2013) J. Chuck Harrell et al.   CLINICAL & EXPERIMENTAL METASTASIS

Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways

(2013) Yi-Chu Yu et al.   Scientific Reports

Quantitative Study of the Dynamic Tumor–Endothelial Cell Interactions through an Integrated Microfluidic Coculture System

(2012) Chunhong Zheng et al.   ANALYTICAL CHEMISTRY

Directed endothelial cell morphogenesis in micropatterned gelatin methacrylate hydrogels

(2012) Mehdi Nikkhah et al.   BIOMATERIALS

Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

(2012) Monika Julia Wolf et al.   CANCER CELL

Engineering of In Vitro 3D Capillary Beds by Self-Directed Angiogenic Sprouting

(2012) Juliana M. Chan et al.   PLoS One

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MCF10A and MDA-MB-231 human breast basal epithelial cell co-culture in silicon micro-arrays

(2011) Mehdi Nikkhah et al.   BIOMATERIALS

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

From the discovery of Vascular Endothelial Growth Factor to the introduction of Avastin in clinical trials - an interview with Napoleone Ferrara

(2011) Domenico Ribatti   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cancer Cells Regulate Biomechanical Properties of Human Microvascular Endothelial Cells

(2011) Claudia Tanja Mierke   JOURNAL OF BIOLOGICAL CHEMISTRY

Actions of the anti-cancer drug suberoylanilide hydroxamic acid (SAHA) on human breast cancer cytoarchitecture in silicon microstructures

(2010) Jeannine S. Strobl et al.   BIOMATERIALS

The cytoskeletal organization of breast carcinoma and fibroblast cells inside three dimensional (3-D) isotropic silicon microstructures

(2010) Mehdi Nikkhah et al.   BIOMATERIALS

Paradoxical Effects of PDGF-BB Overexpression in Endothelial Cells on Engineered Blood Vessels In Vivo

(2009) Patrick Au et al.   AMERICAN JOURNAL OF PATHOLOGY

Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9

(2009) Saša Kenig et al.   CANCER LETTERS

Systemic Analysis of Tumor Cell-Induced Endothelial Calcium Signaling and Junction Disassembly

(2009) Hsin-Hsin Peng et al.   Cellular and Molecular Bioengineering

Vascular permeability, vascular hyperpermeability and angiogenesis

(2008) Janice A. Nagy et al.   ANGIOGENESIS

Cytoskeletal role in differential adhesion patterns of normal fibroblasts and breast cancer cells inside silicon microenvironments

(2008) Mehdi Nikkhah et al.   BIOMEDICAL MICRODEVICES

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

The FGF system has a key role in regulating vascular integrity

(2008) Masahiro Murakami et al.   JOURNAL OF CLINICAL INVESTIGATION

Prevascularization of a Fibrin-Based Tissue Construct Accelerates the Formation of Functional Anastomosis with Host Vasculature

(2008) Xiaofang Chen et al.   TISSUE ENGINEERING PART A