Physical Properties of Implanted Porous Bioscaffolds Regulate Skin Repair: Focusing on Mechanical and Structural Features

Relationships between mechanical properties and drug release from electrospun fibers of PCL and PLGA blends

(2017) Shih-Feng Chou et al.   Journal of the Mechanical Behavior of Biomedical Materials

Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks

(2017) Markus Friedemann et al.   Advanced Healthcare Materials

Biomimetic fibroblast-loaded artificial dermis with “sandwich” structure and designed gradient pore sizes promotes wound healing by favoring granulation tissue formation and wound re-epithelialization

(2016) Yuzhen Wang et al.   Acta Biomaterialia

Polymer chain flexibility-induced differences in fetuin A adsorption and its implications on cell attachment and proliferation

(2016) Moira C. Vyner et al.   Acta Biomaterialia

Substrate stiffness orchestrates epithelial cellular heterogeneity with controlled proliferative pattern via E-cadherin/β-catenin mechanotransduction

(2016) Bingjie Wang et al.   Acta Biomaterialia

Vascular Endothelial Growth Factor Receptor Type 1 Signaling Prevents Delayed Wound Healing in Diabetes by Attenuating the Production of IL-1β by Recruited Macrophages

(2016) Shin-ichiro Okizaki et al.   AMERICAN JOURNAL OF PATHOLOGY

Substrate Stiffness Combined with Hepatocyte Growth Factor Modulates Endothelial Cell Behavior

(2016) Hao Chang et al.   BIOMACROMOLECULES

Overcoming foreign-body reaction through nanotopography: Biocompatibility and immunoisolation properties of a nanofibrous membrane

(2016) Kai Wang et al.   BIOMATERIALS

Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation

(2016) Angelo S. Mao et al.   BIOMATERIALS

Simulation of extracellular matrix remodeling by fibroblast cells in soft three-dimensional bioresorbable scaffolds

(2016) Chaochao Zhou et al.   Biomechanics and Modeling in Mechanobiology

Study of stiffness effects of poly(amidoamine)–poly( n -isopropyl acrylamide) hydrogel on wound healing

(2016) Shixuan Chen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The effects of crosslinkers on physical, mechanical, and cytotoxic properties of gelatin sponge prepared via in-situ gas foaming method as a tissue engineering scaffold

(2016) S. Ali Poursamar et al.   Materials Science & Engineering C-Materials for Biological Applications

Determining the mechanical properties of electrospun poly-ε-caprolactone (PCL) nanofibers using AFM and a novel fiber anchoring technique

(2016) Stephen R. Baker et al.   Materials Science & Engineering C-Materials for Biological Applications

A combinatorial variation in surface chemistry and pore size of three-dimensional porous poly(ε-caprolactone) scaffolds modulates the behaviors of mesenchymal stem cells

(2016) Yingdi Zhao et al.   Materials Science & Engineering C-Materials for Biological Applications

Adsorbed plasma proteins modulate the effects of single-walled carbon nanotubes on neutrophils in blood

(2016) Irina I. Vlasova et al.   Nanomedicine-Nanotechnology Biology and Medicine

Fibrin-based stem cell containing scaffold improves the dynamics of burn wound healing

(2016) Eunna Chung et al.   WOUND REPAIR AND REGENERATION

3D Scaffolds with Different Stiffness but the Same Microstructure for Bone Tissue Engineering

(2015) Guobao Chen et al.   ACS Applied Materials & Interfaces

Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy

(2015) Jun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold

(2015) Elizabeth R. Lorden et al.   BIOMATERIALS

Substrate modulus of 3D-printed scaffolds regulates the regenerative response in subcutaneous implants through the macrophage phenotype and Wnt signaling

(2015) R. Guo et al.   BIOMATERIALS

Roles of YAP in mediating endothelial cell junctional stability and vascular remodeling

(2015) Hyun-Jung Choi et al.   BMB Reports

Regulation of Endothelial Cell Adherence and Elastic Modulus by Substrate Stiffness

(2015) Sharareh Jalali et al.   CELL COMMUNICATION AND ADHESION

Substrate Stiffness Affects Human Keratinocyte Colony Formation

(2015) Hoda Zarkoob et al.   Cellular and Molecular Bioengineering

Scaffolds and cells for tissue regeneration: different scaffold pore sizes—different cell effects

(2015) Ieva Bružauskaitė et al.   CYTOTECHNOLOGY

Substrate elasticity regulates the behavior of human monocyte-derived macrophages

(2015) Katrina M. Adlerz et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Engineering macrophages to control the inflammatory response and angiogenesis

(2015) K.V. Eaton et al.   EXPERIMENTAL CELL RESEARCH

The dynamic anatomy and patterning of skin

(2015) Richard Wong et al.   EXPERIMENTAL DERMATOLOGY

Loureirin B inhibits fibroblast proliferation and extracellular matrix deposition in hypertrophic scar via TGF-β/Smad pathway

(2015) Xiaozhi Bai et al.   EXPERIMENTAL DERMATOLOGY

Three-Dimensional Cell Culture: A Breakthrough in Vivo

(2015) Delphine Antoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MMP-10 Regulates Collagenolytic Activity of Alternatively Activated Resident Macrophages

(2015) Maryam G. Rohani et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mechanical characterization of electrospun gelatin scaffolds cross-linked by glucose

(2015) Kaido Siimon et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Multi-scale mechanical response of freeze-dried collagen scaffolds for tissue engineering applications

(2015) Giovanni S. Offeddu et al.   Journal of the Mechanical Behavior of Biomedical Materials

Highly aligned nanocomposite scaffolds by electrospinning and electrospraying for neural tissue regeneration

(2015) Wei Zhu et al.   Nanomedicine-Nanotechnology Biology and Medicine

A prevascularized subcutaneous device-less site for islet and cellular transplantation

(2015) Andrew R Pepper et al.   NATURE BIOTECHNOLOGY

Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels

(2015) Rajat K. Das et al.   NATURE MATERIALS

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

(2015) Ovijit Chaudhuri et al.   NATURE MATERIALS

Tunable Release of Multiclass Anti-HIV Drugs that are Water-Soluble and Loaded at High Drug Content in Polyester Blended Electrospun Fibers

(2015) Daniel Carson et al.   PHARMACEUTICAL RESEARCH

Volumetric Cortical Bone Porosity Assessment with MR Imaging: Validation and Clinical Feasibility

(2015) Chamith S. Rajapakse et al.   RADIOLOGY

Mechanical strain induces E-cadherin-dependent Yap1 and  -catenin activation to drive cell cycle entry

(2015) B. W. Benham-Pyle et al.   SCIENCE

Controlled Release of Thymosin Beta 4 Using a Collagen–Chitosan Sponge Scaffold Augments Cutaneous Wound Healing and Increases Angiogenesis in Diabetic Rats with Hindlimb Ischemia

(2015) Dongdong Ti et al.   TISSUE ENGINEERING PART A

Scaffold Mean Pore Size Influences Mesenchymal Stem Cell Chondrogenic Differentiation and Matrix Deposition

(2015) Amos Matsiko et al.   TISSUE ENGINEERING PART A

Cutaneous wound healing in aging small mammals: a systematic review

(2015) Dong Joo Kim et al.   WOUND REPAIR AND REGENERATION

A clinical trial of Integra Template for diabetic foot ulcer treatment

(2015) Vickie R. Driver et al.   WOUND REPAIR AND REGENERATION

Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation

(2015) Valentina Doldi et al.   Oncotarget

Porous Hyaluronic Acid Hydrogels for Localized Nonviral DNA Delivery in a Diabetic Wound Healing Model

(2015) Talar Tokatlian et al.   Advanced Healthcare Materials

The Effect of Mesenchymal Stem Cells and Chitosan Gel on Full Thickness Skin Wound Healing in Albino Rats: Histological, Immunohistochemical and Fluorescent Study

(2015) Abir O. El Sadik et al.   PLoS One

Substrate Stiffness Regulates Proinflammatory Mediator Production through TLR4 Activity in Macrophages

(2015) Michelle L. Previtera et al.   PLoS One

Pore size effect of collagen scaffolds on cartilage regeneration

(2014) Qin Zhang et al.   Acta Biomaterialia

The effect of thick fibers and large pores of electrospun poly(ε-caprolactone) vascular grafts on macrophage polarization and arterial regeneration

(2014) Zhihong Wang et al.   BIOMATERIALS

Macrophage polarization in response to ECM coated polypropylene mesh

(2014) Matthew T. Wolf et al.   BIOMATERIALS

Influence of the stiffness of three-dimensional alginate/collagen-I interpenetrating networks on fibroblast biology

(2014) Cristiana Branco da Cunha et al.   BIOMATERIALS

Scaffold pore size modulates in vitro osteogenesis of human adipose-derived stem/stromal cells

(2014) Pinar Yilgor Huri et al.   Biomedical Materials

Preparation of aligned porous chitin nanowhisker foams by directional freeze–casting technique

(2014) Yiming Zhou et al.   CARBOHYDRATE POLYMERS

Effect of negative pressure wound therapy on wound healing

(2014) Chenyu Huang et al.   CURRENT PROBLEMS IN SURGERY

Inhomogeneity of local stiffness in the extracellular matrix scaffold of fibrotic mouse lungs

(2014) Esther Melo et al.   Journal of the Mechanical Behavior of Biomedical Materials

Mechanical properties of alginate hydrogels manufactured using external gelation

(2014) Georgia Kaklamani et al.   Journal of the Mechanical Behavior of Biomedical Materials

Re-epithelialization: advancing epithelium frontier during wound healing

(2014) M. Ben Amar et al.   Journal of the Royal Society Interface

Electrospun Nanofibers as Dressings for Chronic Wound Care: Advances, Challenges, and Future Prospects

(2014) Martina Abrigo et al.   MACROMOLECULAR BIOSCIENCE

Fabrication of dual-pore scaffolds using SLUP (salt leaching using powder) and WNM (wire-network molding) techniques

(2014) Yong Sang Cho et al.   Materials Science & Engineering C-Materials for Biological Applications

Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation

(2014) Yongzhi Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primed 3D injectable microniches enabling low-dosage cell therapy for critical limb ischemia

(2014) Yaqian Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review of Collagen I Hydrogels for Bioengineered Tissue Microenvironments: Characterization of Mechanics, Structure, and Transport

(2014) Elizabeth E. Antoine et al.   TISSUE ENGINEERING PART B-REVIEWS

Mechanical offloading of incisional wounds is associated with transcriptional downregulation of inflammatory pathways in a large animal model

(2014) Michael Januszyk et al.   Organogenesis

Microcryogels as injectable 3-D cellular microniches for site-directed and augmented cell delivery

(2013) Wei Liu et al.   Acta Biomaterialia

Porous Implants Modulate Healing and Induce Shifts in Local Macrophage Polarization in the Foreign Body Reaction

(2013) Eric M. Sussman et al.   ANNALS OF BIOMEDICAL ENGINEERING

The effect of porosity of a biphasic ceramic scaffold on human skeletal stem cell growth and differentiationin vivo

(2013) Alexander Aarvold et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Characterizing the micro-scale elastic modulus of hydrogels for use in regenerative medicine

(2013) Chad D. Markert et al.   Journal of the Mechanical Behavior of Biomedical Materials

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of IGF-1 pathway in lung fibroblast activation

(2013) Chi F Hung et al.   RESPIRATORY RESEARCH

Mechanotherapy: revisiting physical therapy and recruiting mechanobiology for a new era in medicine

(2013) Chenyu Huang et al.   TRENDS IN MOLECULAR MEDICINE

The first systematic analysis of 3D rapid prototyped poly(ε-caprolactone) scaffolds manufactured through BioCell printing: the effect of pore size and geometry on compressive mechanical behaviour andin vitrohMSC viability

(2013) M Domingos et al.   Biofabrication

Severe hidradenitis suppurativa treatment using platelet-rich plasma gel and Hyalomatrix

(2013) Fabio Nicoli et al.   International Wound Journal

Rat an experimental model for burns: A systematic review

(2012) Jorge Kiyoshi Mitsunaga Junior et al.   Acta Cirurgica Brasileira

The mechanical memory of lung myofibroblasts

(2012) Jenna L. Balestrini et al.   Integrative Biology

Student award winner in the undergraduate category for the society of biomaterials 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012

(2012) Anna K. Blakney et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Insulin-Like Growth Factor-1 Promotes Wound Healing in Estrogen-Deprived Mice: New Insights into Cutaneous IGF-1R/ERα Cross Talk

(2012) Elaine Emmerson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Treating a collagen scaffold with a low concentration of nicotine promoted angiogenesis and wound healing

(2012) Pham Hieu Liem et al.   JOURNAL OF SURGICAL RESEARCH

Promotion of diabetic wound healing by collagen scaffold with collagen-binding vascular endothelial growth factor in a diabetic rat model

(2012) Qian Tan et al.   Journal of Tissue Engineering and Regenerative Medicine

Substrate stiffness influences TGF-β1-induced differentiation of bronchial fibroblasts into myofibroblasts in airway remodeling

(2012) YANLING SHI et al.   Molecular Medicine Reports

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

The influence of prefreezing temperature on pore structure in freeze-dried β-TCP scaffolds

(2012) Liulan Lin et al.   PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

(2012) Wanjin Hong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Oxygen levels and the regulation of cell adhesion in the nervous system

(2012) Kathryn L. Crossin   Cell Adhesion & Migration

Construction of the recellularized corneal stroma using porous acellular corneal scaffold

(2011) Jianhui Xiao et al.   BIOMATERIALS

Injectable polyurethane composite scaffolds delay wound contraction and support cellular infiltration and remodeling in rat excisional wounds

(2011) Elizabeth J. Adolph et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Collagen-Gelatin Scaffold Impregnated with bFGF Accelerates Palatal Wound Healing of Palatal Mucosa in Dogs

(2011) Artem Ayvazyan et al.   JOURNAL OF SURGICAL RESEARCH

Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing

(2011) Karen H.L. Kwan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

In Vitro Cartilage Tissue Engineering Using Adipose-Derived Extracellular Matrix Scaffolds Seeded with Adipose-Derived Stem Cells

(2011) Ji Suk Choi et al.   TISSUE ENGINEERING PART A

Genetic Analyses of Integrin Signaling

(2010) S. A. Wickstrom et al.   Cold Spring Harbor Perspectives in Biology

The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

(2009) Ciara M. Murphy et al.   BIOMATERIALS

Freeze-dried acellular dermal matrix graft: Effects of rehydration on physical, chemical, and mechanical properties

(2009) Marco C. Bottino et al.   DENTAL MATERIALS

TGF-β-induced fibroblast activation protein expression, fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM

(2009) He Chen et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Integrin-linked kinase is an adaptor with essential functions during mouse development

(2009) Anika Lange et al.   NATURE

Novel Freeze-Drying Methods to Produce a Range of Collagen–Glycosaminoglycan Scaffolds with Tailored Mean Pore Sizes

(2009) Matthew G. Haugh et al.   TISSUE ENGINEERING PART C-METHODS

Hair Follicle Stem Cells Are Specified and Function in Early Skin Morphogenesis

(2008) Jonathan A. Nowak et al.   Cell Stem Cell

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

(2008) Peter F Davies   Nature clinical practice. Cardiovascular medicine

In vivo measurements of the elastic mechanical properties of human skin by indentation tests

(2007) C. Pailler-Mattei et al.   MEDICAL ENGINEERING & PHYSICS