Periosteal progenitors contribute to load-induced bone formation in adult mice and require primary cilia to sense mechanical stimulation

Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin

(2018) Oriane Duchamp de Lageneste et al.   Nature Communications

Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response

(2018) Behzad Javaheri et al.   Scientific Reports

Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism

(2016) Julia C. Chen et al.   FASEB JOURNAL

Quiescent Bone Lining Cells Are a Major Source of Osteoblasts During Adulthood

(2016) Igor Matic et al.   STEM CELLS

Atypical femoral fracture after receiving antiresorptive drugs in breast cancer patients with bone metastasis

(2016) Seiya Ota et al.   Breast Cancer

The Periosteal Bone Surface is Less Mechano-Responsive than the Endocortical

(2016) Annette I. Birkhold et al.   Scientific Reports

Mechanically stimulated bone cells secrete paracrine factors that regulate osteoprogenitor recruitment, proliferation, and differentiation

(2015) Robert T. Brady et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mesenchymal Cell Contributions to the Stem Cell Niche

(2015) Youmna Kfoury et al.   Cell Stem Cell

Aging Leads to a Dysregulation in Mechanically Driven Bone Formation and Resorption

(2015) Hajar Razi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Highly Selective In Vivo Labeling of Subcutaneous White Adipocyte Precursors with Prx1-Cre

(2015) Joan Sanchez-Gurmaches et al.   Stem Cell Reports

Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment

(2014) Kiminori Yukata et al.   BONE

Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes

(2014) Lee B Meakin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

IL-6 Alters Osteocyte Signaling toward Osteoblasts but Not Osteoclasts

(2014) A.D. Bakker et al.   JOURNAL OF DENTAL RESEARCH

IGF-1 Signaling is Essential for Differentiation of Mesenchymal Stem Cells for Peak Bone Mass

(2014) Janet L. Crane et al.   Bone Research

Periosteum derived stem cells for regenerative medicine proposals: Boosting current knowledge

(2014) Concetta Ferretti   World Journal of Stem Cells

Prx1 and 3.2kb Col1a1 promoters target distinct bone cell populations in transgenic mice

(2013) Zhufeng Ouyang et al.   BONE

Osteocytes: Master Orchestrators of Bone

(2013) Mitchell B. Schaffler et al.   CALCIFIED TISSUE INTERNATIONAL

Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo

(2013) Kristen L. Lee et al.   FASEB JOURNAL

Periosteal cells are a major source of soft callus in bone fracture

(2013) Hiroki Murao et al.   JOURNAL OF BONE AND MINERAL METABOLISM

The Relevance of Mouse Models for Investigating Age-Related Bone Loss in Humans

(2013) R. L. Jilka   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

(2013) Christian Alexandro Clement et al.   Cell Reports

Periosteal-derived cells for bone bioengineering: a promising candidate

(2012) Igor Iuco Castro-Silva et al.   CLINICAL ORAL IMPLANTS RESEARCH

Mechanical regulation of signaling pathways in bone

(2012) William R. Thompson et al.   GENE

Antiresorptive drugs (bisphosphonates), atypical fractures and rebound effect: new evidence of similitude

(2012) Marcus Zulian Teixeira   Homeopathy

Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factor

(2012) Yan Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanosensing by the Primary Cilium: Deletion of Kif3A Reduces Bone Formation Due to Loading

(2012) Sara Temiyasathit et al.   PLoS One

Primary Cilia-Mediated Mechanotransduction in Human Mesenchymal Stem Cells

(2012) David A. Hoey et al.   STEM CELLS

A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells

(2011) David A. Hoey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanobiological regulation of the remodelling cycle in trabecular bone and possible biomechanical pathways for osteoporosis

(2010) Bríanne M. Mulvihill et al.   CLINICAL BIOMECHANICS

Identification of Signaling Pathways Regulating Primary Cilium Length and Flow-Mediated Adaptation

(2010) Tatiana Y. Besschetnova et al.   CURRENT BIOLOGY

Aging changes mechanical loading thresholds for bone formation in rats

(2010) Charles H. Turner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum

(2009) Aya Kawanami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics

(2009) E. J. Arnsdorf et al.   JOURNAL OF CELL SCIENCE

A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow

(2009) Masoud Soleimani et al.   Nature Protocols

The Periosteum as a Cellular Source for Functional Tissue Engineering

(2009) Emily J. Arnsdorf et al.   TISSUE ENGINEERING PART A

Skeletal Cell Fate Decisions Within Periosteum and Bone Marrow During Bone Regeneration

(2008) Céline Colnot   JOURNAL OF BONE AND MINERAL RESEARCH