TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in mice

Immunomodulatory effects of soluble factors secreted by feline adipose tissue-derived mesenchymal stem cells

(2017) Hyung-Kyu Chae et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

TSG-6 Secreted by Human Adipose Tissue-derived Mesenchymal Stem Cells Ameliorates DSS-induced colitis by Inducing M2 Macrophage Polarization in Mice

(2017) Woo-Jin Song et al.   Scientific Reports

Canine adipose tissue-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating T cells in rats

(2016) Hyun-Wook Kim et al.   Journal of Veterinary Science

Therapeutic Potential of Secreted Molecules Derived from Human Amniotic Fluid Mesenchymal Stem/Stroma Cells in a Mice Model of Colitis

(2016) E. Legaki et al.   Stem Cell Reviews and Reports

Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis

(2016) Tae-Hoon Shin et al.   Cell Death & Disease

TSG-6 secreted by human umbilical cord-MSCs attenuates severe burn-induced excessive inflammation via inhibiting activations of P38 and JNK signaling

(2016) Lingying Liu et al.   Scientific Reports

Therapeutic Potential of Secreted Molecules Derived from Human Amniotic Fluid Mesenchymal Stem/Stroma Cells in a Mice Model of Colitis

(2016) E. Legaki et al.   Stem Cell Reviews and Reports

Intraperitoneal injection (IP), Intravenous injection (IV) or anal injection (AI)? Best way for mesenchymal stem cells transplantation for colitis

(2016) Min Wang et al.   Scientific Reports

Human mesenchymal stromal cells exert HGF dependent cytoprotective effects in a human relevant pre-clinical model of COPD

(2016) Helen Kennelly et al.   Scientific Reports

Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism

(2016) Anoop Babu Vasandan et al.   Scientific Reports

Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-α Stimulated Gene/Protein 6

(2016) Zhigang He et al.   Scientific Reports

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mesenchymal Stem Cells Recruit Macrophages to Alleviate Experimental Colitis Through TGFβ1

(2015) Weixin Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine

(2015) Emanuela Sala et al.   GASTROENTEROLOGY

Human Umbilical Cord Blood Mesenchymal Stem Cell-Derived PGE2and TGF-β1 Alleviate Atopic Dermatitis by Reducing Mast Cell Degranulation

(2015) Hyung-Sik Kim et al.   STEM CELLS

Changes in Foxp3-Positive Regulatory T Cell Number in the Intestine of Dogs With Idiopathic Inflammatory Bowel Disease and Intestinal Lymphoma

(2015) S. Maeda et al.   VETERINARY PATHOLOGY

Potential therapeutic utility of mesenchymal stem cells in inflammatory bowel disease in mice

(2014) Ahmed G. Abdel Salam et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

(2014) Ying Wang et al.   NATURE IMMUNOLOGY

Equine Mesenchymal Stem Cells Inhibit T Cell Proliferation Through Different Mechanisms Depending on Tissue Source

(2014) Danielle D. Carrade Holt et al.   STEM CELLS AND DEVELOPMENT

Human Umbilical Cord Blood Mesenchymal Stem Cells Reduce Colitis in Mice by Activating NOD2 Signaling to COX2

(2013) Hyung–Sik Kim et al.   GASTROENTEROLOGY

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

(2013) Dan Knights et al.   GUT

TSG-6 Released from Intradermally Injected Mesenchymal Stem Cells Accelerates Wound Healing and Reduces Tissue Fibrosis in Murine Full-Thickness Skin Wounds

(2013) Yu Qi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Analysis using canine peripheral blood for establishing in vitro conditions for monocyte differentiation into macrophages for Leishmania chagasi infection and T-cell subset purification

(2013) Kelvinson Fernandes Viana et al.   VETERINARY PARASITOLOGY

Mesenchymal stem cells alleviate TNBS-induced colitis by modulating inflammatory and autoimmune responses

(2013) Qian-Qian Chen   WORLD JOURNAL OF GASTROENTEROLOGY

Systemic Infusion of Bone Marrow-Derived Mesenchymal Stem Cells for Treatment of Experimental Colitis in Mice

(2012) Xiao-Wen He et al.   DIGESTIVE DISEASES AND SCIENCES

Transplantation of Mesenchymal Stem Cells Promotes an Alternative Pathway of Macrophage Activation and Functional Recovery after Spinal Cord Injury

(2012) Hideaki Nakajima et al.   JOURNAL OF NEUROTRAUMA

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

The gut microbiota in IBD

(2012) Chaysavanh Manichanh et al.   Nature Reviews Gastroenterology & Hepatology

Intraperitoneal but Not Intravenous Cryopreserved Mesenchymal Stromal Cells Home to the Inflamed Colon and Ameliorate Experimental Colitis

(2012) Morgana T. L. Castelo-Branco et al.   PLoS One

Mesenchymal Stem Cells Attenuate Peritoneal Injury through Secretion of TSG-6

(2012) Nan Wang et al.   PLoS One

Human Mesenchymal Stem/Stromal Cells Cultured as Spheroids are Self-activated to Produce Prostaglandin E2 that Directs Stimulated Macrophages into an Anti-inflammatory Phenotype

(2012) Joni H. YlÖstalo et al.   STEM CELLS

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Mice Trinitrobenzene Sulfonic Acid (TNBS)-Induced Colitis

(2011) Lu Liang et al.   CELL TRANSPLANTATION

Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6

(2011) Gavin W. Roddy et al.   STEM CELLS

Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6

(2011) Svitlana Danchuk et al.   Stem Cell Research & Therapy

Human Bone Marrow–Derived Clonal Mesenchymal Stem Cells Inhibit Inflammation and Reduce Acute Pancreatitis in Rats

(2010) Kyung Hee Jung et al.   GASTROENTEROLOGY

Human Gingiva-Derived Mesenchymal Stem Cells Elicit Polarization of M2 Macrophages and Enhance Cutaneous Wound Healing

(2010) Qun-Zhou Zhang et al.   STEM CELLS

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Adipose-Derived Mesenchymal Stem Cells Alleviate Experimental Colitis by Inhibiting Inflammatory and Autoimmune Responses

(2008) Manuel A. González et al.   GASTROENTEROLOGY

Subcutaneous adipose tissue–derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)–induced colitis in rats

(2008) Yugo Ando et al.   INFLAMMATORY BOWEL DISEASES