TSG-6 secreted by human umbilical cord-MSCs attenuates severe burn-induced excessive inflammation via inhibiting activations of P38 and JNK signaling

Alpha-Pinene Exhibits Anti-Inflammatory Activity Through the Suppression of MAPKs and the NF-κB Pathway in Mouse Peritoneal Macrophages

(2015) Dae-Seung Kim et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Anti-inflammatory effect of Impatiens textori Miq. extract via inhibition of NLRP3 inflammasome activation in in vitro and in vivo experimental models

(2015) Xiao Sun et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-Inflammatory Protein Tumor Necrosis Factor-α–Stimulated Protein 6 (TSG-6) Promotes Early Gingival Wound Healing: An In Vivo Study

(2015) Stacy R. Beltran et al.   JOURNAL OF PERIODONTOLOGY

Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation

(2015) Song-Xue Guo et al.   Journal of Translational Medicine

Negative feedback–defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL

(2015) Benshang Li et al.   NATURE MEDICINE

The selective mGluR5 agonist CHPG attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells

(2015) Jun-Ling Qiu et al.   NEUROCHEMISTRY INTERNATIONAL

Mesenchymal stem cells alleviate airway inflammation and emphysema in COPD through down-regulation of cyclooxygenase-2 via p38 and ERK MAPK pathways

(2015) Wen Gu et al.   Scientific Reports

Tumor necrosis factor-inducible gene 6 promotes liver regeneration in mice with acute liver injury

(2015) Sihyung Wang et al.   Stem Cell Research & Therapy

Alert Cell Strategy: Mechanisms of Inflammatory Response and Organ Protection

(2014) Noboru Hatakeyama et al.   CURRENT PHARMACEUTICAL DESIGN

Mesenchymal stem cells inhibit lipopolysaccharide-induced inflammatory responses of BV2 microglial cells through TSG-6

(2014) Yi Liu et al.   Journal of Neuroinflammation

Human Umbilical Cord Mesenchymal Stem Cells Transplantation Promotes Cutaneous Wound Healing of Severe Burned Rats

(2014) Lingying Liu et al.   PLoS One

Acid Sphingomyelinase Serum Activity Predicts Mortality in Intensive Care Unit Patients after Systemic Inflammation: A Prospective Cohort Study

(2014) Matthias Kott et al.   PLoS One

Effects of Soluble Epoxide Hydrolase Deficiency on Acute Pancreatitis in Mice

(2014) Ahmed Bettaieb et al.   PLoS One

TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo

(2014) Ryang Hwa Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basic fibroblast growth factor/vascular endothelial growth factor in the serum from severe burn patients stimulates the proliferation of cultured human umbilical cord mesenchymal stem cells via activation of Notch signaling pathways

(2013) Ling-Ying Liu et al.   Journal of Trauma and Acute Care Surgery

Immediate splenectomy down-regulates the MAPK–NF-κB signaling pathway in rat brain after severe traumatic brain injury

(2013) Weihua Chu et al.   Journal of Trauma and Acute Care Surgery

Angiotensin II Produces Nociceptive Behavior through Spinal AT1 Receptor-Mediated p38 Mitogen-Activated Protein Kinase Activation in Mice

(2013) Wataru Nemoto et al.   Molecular Pain

Administration of TSG-6 improves memory after traumatic brain injury in mice

(2013) Jun Watanabe et al.   NEUROBIOLOGY OF DISEASE

IFN-γ Stimulated Human Umbilical-Tissue-Derived Cells Potently Suppress NK Activation and Resist NK-Mediated Cytotoxicity In Vitro

(2013) Cariosa Noone et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal Stem Cells Attenuate Peritoneal Injury through Secretion of TSG-6

(2012) Nan Wang et al.   PLoS One

High-Mobility Group Box-1 Induces Proinflammatory Cytokines Production of Kupffer Cells through TLRs-Dependent Signaling Pathway after Burn Injury

(2012) Xu-Lin Chen et al.   PLoS One

How mesenchymal stem cells interact with tissue immune responses

(2012) Yufang Shi et al.   TRENDS IN IMMUNOLOGY

Novel mechanism for mesenchymal stem cells in attenuating peritoneal adhesion: accumulating in the lung and secreting tumor necrosis factor α-stimulating gene-6

(2012) Nan Wang et al.   Stem Cell Research & Therapy

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation

(2011) Darwin J Prockop et al.   MOLECULAR THERAPY

Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6

(2011) Gavin W. Roddy et al.   STEM CELLS

Mesenchymal stem cells: Paracrine signaling and differentiation during cutaneous wound repair

(2010) Anne M. Hocking et al.   EXPERIMENTAL CELL RESEARCH

Burns as a model of SIRS

(2010) Punam Dahiya   Frontiers in Bioscience-Landmark

Mesenchymal stem cell transplantation modulates neuroinflammation in focal cerebral ischemia: Contribution of fractalkine and IL-5

(2010) Abdullah Md. Sheikh et al.   NEUROBIOLOGY OF DISEASE

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Mechanisms involved in the therapeutic properties of mesenchymal stem cells

(2009) Lindolfo da Silva Meirelles et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Role of p38 MAPK in Burn-Induced Intestinal Barrier Breakdown

(2009) Todd W. Costantini et al.   JOURNAL OF SURGICAL RESEARCH

Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy

(2008) Massimiliano Gnecchi et al.   CIRCULATION RESEARCH