Phospholipase D1 regulation of TNF-alpha protects against responses to LPS

Oligophrenin1 protects mice against myocardial ischemia and reperfusion injury by modulating inflammation and myocardial apoptosis

(2016) Christina Niermann et al.   CELLULAR SIGNALLING

Platelets induce apoptosis via membrane-bound FasL

(2015) R. I. Schleicher et al.   BLOOD

Phospholipase D2 drives mortality in sepsis by inhibiting neutrophil extracellular trap formation and down-regulating CXCR2

(2015) Sung Kyun Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of oligophrenin1 leads to uncontrolled Rho activation and increased thrombus formation in mice

(2015) A. Fotinos et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The phospholipase D superfamily as therapeutic targets

(2015) Michael A. Frohman   TRENDS IN PHARMACOLOGICAL SCIENCES

Pivotal Role of Phospholipase D1 in Tumor Necrosis Factor-α–Mediated Inflammation and Scar Formation after Myocardial Ischemia and Reperfusion in Mice

(2014) Tanja Schönberger et al.   AMERICAN JOURNAL OF PATHOLOGY

Phospholipase D1 is required for lipopolysaccharide-induced tumor necrosis factor-α expression and production through S6K1/JNK/c-Jun pathway in Raw 264.7 cells

(2014) Cheong-Hae Oh et al.   CYTOKINE

Cellular and Physiological Roles for Phospholipase D1 in Cancer

(2014) Yi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase D1 Plays a Key Role in TNF-α Signaling

(2014) Swaminathan Sethu et al.   JOURNAL OF IMMUNOLOGY

The role of platelets in sepsis

(2014) Cornelis van ’t Veer et al.   THROMBOSIS AND HAEMOSTASIS

Pharmacological Inhibition of Phospholipase D Protects Mice From Occlusive Thrombus Formation and Ischemic Stroke—Brief Report

(2013) David Stegner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Phospholipase D1 Has a Pivotal Role in Interleukin-1 -Driven Chronic Autoimmune Arthritis through Regulation of NF- B, Hypoxia-Inducible Factor 1 , and FoxO3a

(2013) D. W. Kang et al.   MOLECULAR AND CELLULAR BIOLOGY

Deficiencies of the Lipid-Signaling Enzymes Phospholipase D1 and D2 Alter Cytoskeletal Organization, Macrophage Phagocytosis, and Cytokine-Stimulated Neutrophil Recruitment

(2013) Wahida H. Ali et al.   PLoS One

Intracellular cyclophilin A is an important Ca2+ regulator in platelets and critically involved in arterial thrombus formation

(2012) M. Elvers et al.   BLOOD

Whole-Blood Thrombin Generation Monitored with a Calibrated Automated Thrombogram-Based Assay

(2012) M. Ninivaggi et al.   CLINICAL CHEMISTRY

Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes

(2012) Chunfa Huang et al.   EXPERIMENTAL CELL RESEARCH

iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against Listeria and Responses to LPS

(2012) D. R. McIlwain et al.   SCIENCE

Extracellular protein disulfide isomerase regulates feedback activation of platelet thrombin generation via modulation of coagulation factor binding

(2011) K. JURK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Phospholipase D2 Mediates Acute Aldosterone Secretion in Response to Angiotensin II in Adrenal Glomerulosa Cells

(2010) Haixia Qin et al.   ENDOCRINOLOGY

Non-synonymous single-nucleotide polymorphisms associated with blood pressure and hypertension

(2010) K-W Hong et al.   JOURNAL OF HUMAN HYPERTENSION

Phospholipase D2 Ablation Ameliorates Alzheimer's Disease-Linked Synaptic Dysfunction and Cognitive Deficits

(2010) T. G. Oliveira et al.   JOURNAL OF NEUROSCIENCE

Phospholipase D1 Mediates TNFα-Induced Inflammation in a Murine Model of TNFα-Induced Peritonitis

(2010) Swaminathan Sethu et al.   PLoS One

SEPSIS-ASSOCIATED DISSEMINATED INTRAVASCULAR COAGULATION AND THROMBOEMBOLIC DISEASE

(2010) Nicola Semeraro et al.   Mediterranean Journal of Hematology and Infectious Diseases

Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells

(2009) David A. Foster   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Thrombocytopenia and thrombosis in disseminated intravascular coagulation (DIC)

(2009) C. S. Kitchens   Hematology-American Society of Hematology Education Program

Cleavage of phospholipase D1 by caspase promotes apoptosis via modulation of the p53-dependent cell death pathway

(2008) Y H Jang et al.   CELL DEATH AND DIFFERENTIATION