Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics

Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex

(2016) Jason R. Gerstner et al.   BMC GENOMICS

Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma

(2015) Xiting Yan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rationale, design and methods for the 22 year follow-up of the Western Australian Pregnancy Cohort (Raine) Study

(2015) Leon M. Straker et al.   BMC PUBLIC HEALTH

The revised 2014 GINA strategy report

(2015) Louis-Philippe Boulet et al.   CURRENT OPINION IN PULMONARY MEDICINE

Novel concepts in airway inflammation and remodelling in asthma

(2015) Sejal Saglani et al.   EUROPEAN RESPIRATORY JOURNAL

Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations

(2015) Stephen J. Teach et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation

(2015) Priya Rajavelu et al.   JOURNAL OF CLINICAL INVESTIGATION

The immunology of asthma

(2015) Bart N Lambrecht et al.   NATURE IMMUNOLOGY

Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication

(2015) Yury A. Bochkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities

(2014) S. Vallath et al.   EUROPEAN RESPIRATORY JOURNAL

The cell biology of asthma

(2014) David J. Erle et al.   JOURNAL OF CELL BIOLOGY

Normalization of RNA-seq data using factor analysis of control genes or samples

(2014) Davide Risso et al.   NATURE BIOTECHNOLOGY

A GM-CSF/IL-33 Pathway Facilitates Allergic Airway Responses to Sub-Threshold House Dust Mite Exposure

(2014) Alba Llop-Guevara et al.   PLoS One

Deficiency of gp91phoxInhibits Allergic Airway Inflammation

(2013) Carla M. Sevin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Constitutive HER2 Signaling Promotes Breast Cancer Metastasis through Cellular Senescence

(2013) P. D. Angelini et al.   CANCER RESEARCH

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

(2013) Klaus Bønnelykke et al.   NATURE GENETICS

TH2, allergy and group 2 innate lymphoid cells

(2013) Paula Licona-Limón et al.   NATURE IMMUNOLOGY

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

(2013) Simon Anders et al.   Nature Protocols

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

AGR2 Is Induced in Asthma and Promotes Allergen-Induced Mucin Overproduction

(2012) Bradley W. Schroeder et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations

(2012) Philip H. Quanjer et al.   EUROPEAN RESPIRATORY JOURNAL

Pathway analysis of genome-wide association study on asthma

(2012) Gwan Gyu Song et al.   HUMAN IMMUNOLOGY

Viral infections and atopy in asthma pathogenesis: new rationales for asthma prevention and treatment

(2012) Patrick G Holt et al.   NATURE MEDICINE

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

E-cadherin gene polymorphisms in asthma patients using inhaled corticosteroids

(2011) D. Ierodiakonou et al.   EUROPEAN RESPIRATORY JOURNAL

Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo

(2011) Anthony Bosco et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Periostin Regulates Goblet Cell Metaplasia in a Model of Allergic Airway Inflammation

(2011) S. Sehra et al.   JOURNAL OF IMMUNOLOGY

Randomized Trial of Omalizumab (Anti-IgE) for Asthma in Inner-City Children

(2011) William W. Busse et al.   NEW ENGLAND JOURNAL OF MEDICINE

The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation

(2011) S Post et al.   THORAX

E-cadherin: gatekeeper of airway mucosa and allergic sensitization

(2011) Martijn C. Nawijn et al.   TRENDS IN IMMUNOLOGY

Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma

(2010) Timothy D. Le Cras et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma

(2010) Biju Thomas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of viral respiratory infections in asthma and asthma exacerbations

(2010) William W Busse et al.   LANCET

Decreased activation of inflammatory networks during acute asthma exacerbations is associated with chronic airflow obstruction

(2010) A Bosco et al.   Mucosal Immunology

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation of Neuregulin 1β1–Induced MUC5AC and MUC5B Expression in Human Airway Epithelium

(2009) Rachel Kettle et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype

(2009) R. H. Dougherty et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma

(2009) L. G. Wood et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Elucidation of asthma phenotypes in atopic teenagers through parallel immunophenotypic and clinical profiling

(2009) Elysia M. Hollams et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Network Modeling Approach to Analysis of the Th2 Memory Responses Underlying Human Atopic Disease

(2009) Anthony Bosco et al.   JOURNAL OF IMMUNOLOGY

Severe Exacerbations and Decline in Lung Function in Asthma

(2008) Paul M. O'Byrne et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels

(2008) Amanda R. Hajek et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Insights into the Organization of Biochemical Regulatory Networks Using Graph Theory Analyses

(2008) Avi Ma'ayan   JOURNAL OF BIOLOGICAL CHEMISTRY

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

(2008) Edy Y Kim et al.   NATURE MEDICINE