An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells

Surgical repair in humans after traumatic nerve injury provides limited functional neural regeneration in adults

(2017) Winnie A. Palispis et al.   EXPERIMENTAL NEUROLOGY

Stem Cell Transplantation for Peripheral Nerve Regeneration: Current Options and Opportunities

(2017) Liangfu Jiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Engineered neural tissue with Schwann cell differentiated human dental pulp stem cells: potential for peripheral nerve repair?

(2017) Kathleen Sanen et al.   Journal of Tissue Engineering and Regenerative Medicine

Human Neural Stem Cell Therapy for Chronic Ischemic Stroke: Charting Progress from Laboratory to Patients

(2017) John D. Sinden et al.   STEM CELLS AND DEVELOPMENT

Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study

(2016) Dheeraj Kalladka et al.   LANCET

Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair

(2016) Kulraj Singh Bhangra et al.   Stem Cells International

Peripheral nerve regeneration: Experimental strategies and future perspectives

(2015) Alessandro Faroni et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat sciatic nerve

(2015) Melanie Georgiou et al.   BIOMATERIALS

Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves

(2015) Anne-Laure Cattin et al.   CELL

Optimising contraction and alignment of cellular collagen hydrogels to achieve reliable and consistent engineered anisotropic tissue

(2015) Caitriona O’Rourke et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Allogenic benefit in stem cell therapy: cardiac repair and regeneration

(2015) R. Al-Daccak et al.   TISSUE ANTIGENS

Peripheral Nerve Reconstruction after Injury: A Review of Clinical and Experimental Therapies

(2014) D. Grinsell et al.   Biomed Research International

Clinical-Grade Human Neural Stem Cells Promote Reparative Neovascularization in Mouse Models of Hindlimb Ischemia

(2013) Rajesh Katare et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Engineered neural tissue for peripheral nerve repair

(2013) Melanie Georgiou et al.   BIOMATERIALS

In Vivo and in Vitro Characterization of the Angiogenic Effect of CTX0E03 Human Neural Stem Cells

(2013) Caroline Hicks et al.   CELL TRANSPLANTATION

Human dental pulp stem cells can differentiate into Schwann cells and promote and guide neurite outgrowth in an aligned tissue-engineered collagen construct in vitro

(2013) Wendy Martens et al.   FASEB JOURNAL

Advances in peripheral nerve regeneration

(2013) Jami Scheib et al.   Nature Reviews Neurology

A systematic review of animal models used to study nerve regeneration in tissue-engineered scaffolds

(2012) Diana Angius et al.   BIOMATERIALS

Effect of modulating macrophage phenotype on peripheral nerve repair

(2012) Nassir Mokarram et al.   BIOMATERIALS

Regenerative effect of adipose tissue-derived stem cells transplantation using nerve conduit therapy on sciatic nerve injury in rats

(2012) Bai-Shuan Liu et al.   Journal of Tissue Engineering and Regenerative Medicine

Allotransplanted Neurons Used to Repair Peripheral Nerve Injury Do Not Elicit Overt Immunogenicity

(2012) Weimin Liu et al.   PLoS One

Experimental and Clinical Evidence for Use of Decellularized Nerve Allografts in Peripheral Nerve Gap Reconstruction

(2012) Mark Szynkaruk et al.   TISSUE ENGINEERING PART B-REVIEWS

The relationship between nerve conduction velocity and fiber morphology during peripheral nerve regeneration

(2012) Masayoshi Ikeda et al.   Brain and Behavior

Neuronal Differentiation of Human Adipose Tissue–Derived Stem Cells for Peripheral Nerve Regeneration In Vivo

(2011) Thomas Scholz   ARCHIVES OF SURGERY

FDA approved guidance conduits and wraps for peripheral nerve injury: A review of materials and efficacy

(2011) S. Kehoe et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Implantation Site and Lesion Topology Determine Efficacy of a Human Neural Stem Cell Line in a Rat Model of Chronic Stroke

(2011) Edward J. Smith et al.   STEM CELLS

Next Generation Nerve Guides: Materials, Fabrication, Growth Factors, and Cell Delivery

(2011) Juliet H.A. Bell et al.   TISSUE ENGINEERING PART B-REVIEWS

Biomaterials for the Development of Peripheral Nerve Guidance Conduits

(2011) Alexander R. Nectow et al.   TISSUE ENGINEERING PART B-REVIEWS

Repairing injured peripheral nerves: Bridging the gap

(2010) Ronald Deumens et al.   PROGRESS IN NEUROBIOLOGY

Automated, serum-free production of CTX0E03: a therapeutic clinical grade human neural stem cell line

(2009) R. J. Thomas et al.   BIOTECHNOLOGY LETTERS