Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa: a connection between quorum sensing and c-di-GMP

Terrein performs antitumor functions on esophageal cancer cells by inhibiting cell proliferation and synergistic interaction with cisplatin

(2017) Yanqing Wu et al.   Oncology Letters

Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model

(2017) Jing Luo et al.   PLoS One

Quorum sensing signal–response systems in Gram-negative bacteria

(2016) Kai Papenfort et al.   NATURE REVIEWS MICROBIOLOGY

Using Surface Enhanced Raman Scattering to Analyze the Interactions of Protein Receptors with Bacterial Quorum Sensing Modulators

(2015) Celina Costas et al.   ACS Nano

Development of Potent Inhibitors of Pyocyanin Production in Pseudomonas aeruginosa

(2015) Laura C. Miller et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phenazine virulence factor binding to extracellular DNA is important for Pseudomonas aeruginosa biofilm formation

(2015) Theerthankar Das et al.   Scientific Reports

A Drug-Repositioning Screening Identifies Pentetic Acid as a Potential Therapeutic Agent for Suppressing the Elastase-Mediated Virulence of Pseudomonas aeruginosa

(2014) Mia Gi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthetic (+)-terrein suppresses interleukin-6/soluble interleukin-6 receptor induced-secretion of vascular endothelial growth factor in human gingival fibroblasts

(2014) Hiroki Mandai et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Diguanylate cyclase NicD-based signalling mechanism of nutrient-induced dispersion byPseudomonas aeruginosa

(2014) Ankita Basu Roy et al.   MOLECULAR MICROBIOLOGY

The hierarchy quorum sensing network in Pseudomonas aeruginosa

(2014) Jasmine Lee et al.   Protein & Cell

10 x '20 Progress--Development of New Drugs Active Against Gram-Negative Bacilli: An Update From the Infectious Diseases Society of America

(2013) H. W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Applying insights from biofilm biology to drug development — can a new approach be developed?

(2013) Thomas Bjarnsholt et al.   NATURE REVIEWS DRUG DISCOVERY

Terrein induces apoptosis in HeLa human cervical carcinoma cells through p53 and ERK regulation

(2013) YUWARAT PORAMEESANAPORN et al.   ONCOLOGY REPORTS

A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

(2013) C. T. O'Loughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control

(2013) S. T. Rutherford et al.   Cold Spring Harbor Perspectives in Medicine

Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis

(2012) Dimpy Kalia et al.   CHEMICAL SOCIETY REVIEWS

A Tangled Web: Regulatory Connections between Quorum Sensing and Cyclic Di-GMP

(2012) D. Srivastava et al.   JOURNAL OF BACTERIOLOGY

Pyocyanin Promotes Extracellular DNA Release in Pseudomonas aeruginosa

(2012) Theerthankar Das et al.   PLoS One

Thiolactone modulators of quorum sensing revealed through library design and screening

(2011) Christine E. McInnis et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Microtiter Dish Biofilm Formation Assay

(2011) George A. O'Toole   Jove-Journal of Visualized Experiments

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP

(2010) P. V. Krasteva et al.   SCIENCE

Bacterial Quorum-Sensing Network Architectures

(2009) Wai-Leung Ng et al.   Annual Review of Genetics

Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

(2009) MARIA VAN GENNIP et al.   APMIS

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

(2009) N. Barraud et al.   JOURNAL OF BACTERIOLOGY

Covalent Inhibition of Bacterial Quorum Sensing

(2009) Neri Amara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Connecting Quorum Sensing, c-di-GMP, Pel Polysaccharide, and Biofilm Formation in Pseudomonas aeruginosa through Tyrosine Phosphatase TpbA (PA3885)

(2009) Akihiro Ueda et al.   PLoS Pathogens

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Acquired vancomycin resistance in clinically relevant pathogens

(2008) Guido Werner et al.   Future Microbiology

Tolerance of dormant and active cells in Pseudomonas aeruginosa PA01 biofilm to antimicrobial agents

(2008) Jaeeun Kim et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY