A novel phosphoester-based cationic co-polymer nanocarrier delivers chimeric antigen receptor plasmid and exhibits anti-tumor effect

In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers

(2017) Tyrel T. Smith et al.   Nature Nanotechnology

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

(2017) Fengmei Pi et al.   Nature Nanotechnology

Delivery of VP1 siRNA to inhibit the EV71 virus using functionalized silver nanoparticles through ROS-mediated signaling pathways

(2017) Yinghua Li et al.   RSC Advances

Polyethylenimine: a very useful ionic polymer in the design of immobilized enzyme biocatalysts

(2017) Jose J. Virgen-Ortíz et al.   Journal of Materials Chemistry B

Rethinking cancer nanotheranostics

(2017) Hongmin Chen et al.   Nature Reviews Materials

Light-Responsive Biodegradable Nanomedicine Overcomes Multidrug Resistance via NO-Enhanced Chemosensitization

(2016) Jing Fan et al.   ACS Applied Materials & Interfaces

Site-specific integration of CAR gene into Jurkat T cells with a linear close-ended AAV-based DNA vector for CAR-T engineering

(2016) Yun Zhang et al.   BIOTECHNOLOGY LETTERS

Monoclonal antibody-tagged polyethylenimine (PEI)/poly(lactide) (PLA) nanoparticles for the enhanced delivery of doxorubicin in HER-positive breast cancers

(2016) Ning Cui et al.   RSC Advances

Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen Receptor

(2015) James N. Kochenderfer et al.   JOURNAL OF CLINICAL ONCOLOGY

Improving Paclitaxel Delivery: In Vitro and In Vivo Characterization of PEGylated Polyphosphoester-Based Nanocarriers

(2015) Fuwu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

(2015) Daniel W Lee et al.   LANCET

A novel self-assembled sandwich nanomedicine for NIR-responsive release of NO

(2015) Jing Fan et al.   Nanoscale

Degradable polyphosphoester-based silver-loaded nanoparticles as therapeutics for bacterial lung infections

(2015) Fuwu Zhang et al.   Nanoscale

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

(2014) M. L. Davila et al.   Science Translational Medicine

Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers

(2014) Lian Jin et al.   Theranostics

Multi-responsive hydrogels derived from the self-assembly of tethered allyl-functionalized racemic oligopeptides

(2014) Xun He et al.   Journal of Materials Chemistry B

Nanoparticles: Detection of Single Nanoparticles and Lentiviruses Using Microcavity Resonance Broadening (Adv. Mater. 39/2013)

(2013) Linbo Shao et al.   ADVANCED MATERIALS

AAV2 production with optimized N/P ratio and PEI-mediated transfection results in low toxicity and high titer for in vitro and in vivo applications

(2013) Xinping Huang et al.   JOURNAL OF VIROLOGICAL METHODS

CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

(2013) R. J. Brentjens et al.   Science Translational Medicine

Synthesis and In Vivo Pharmacokinetic Evaluation of Degradable Shell Cross-Linked Polymer Nanoparticles with Poly(carboxybetaine) versus Poly(ethylene glycol) Surface-Grafted Coatings

(2012) Ang Li et al.   ACS Nano

Rapid and Versatile Construction of Diverse and Functional Nanostructures Derived from a Polyphosphoester-Based Biomimetic Block Copolymer System

(2012) Shiyi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

(2011) M. Kalos et al.   Science Translational Medicine

Immunotherapy of Metastatic Melanoma Using Genetically Engineered GD2-Specific T cells

(2009) E. Yvon et al.   CLINICAL CANCER RESEARCH

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Identification of Gammaretroviruses Constitutively Released from Cell Lines Used for Human Immunodeficiency Virus Research

(2008) Y. Takeuchi et al.   JOURNAL OF VIROLOGY