Overexpression of Wild-Type but Not C134W Mutant FOXL2 Enhances GnRH-Induced Cell Apoptosis by Increasing GnRH Receptor Expression in Human Granulosa Cell Tumors

Discovery of novel protein partners of the transcription factor FOXL2 provides insights into its physiopathological roles

(2012) David L'Hôte et al.   HUMAN MOLECULAR GENETICS

The Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours

(2012) Roseanne Rosario et al.   PLoS One

Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W)

(2010) J-H Kim et al.   ONCOGENE

Functional Exploration of the Adult Ovarian Granulosa Cell Tumor-Associated Somatic FOXL2 Mutation p.Cys134Trp (c.402C>G)

(2010) Bérénice A. Benayoun et al.   PLoS One

Aromatase Is a Direct Target of FOXL2: C134W in Granulosa Cell Tumors via a Single Highly Conserved Binding Site in the Ovarian Specific Promoter

(2010) Nicholas I. Fleming et al.   PLoS One

Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter

(2010) Jean M Escudero et al.   Journal of Ovarian Research

Epidermal Growth Factor-Induced GnRH-II Synthesis Contributes to Ovarian Cancer Cell Invasion

(2009) Song Ling Poon et al.   MOLECULAR ENDOCRINOLOGY

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

(2009) Sohrab P. Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Specificity of the FOXL2 c.402C>G Somatic Mutation: A Survey of Solid Tumors

(2009) Kasmintan A. Schrader et al.   PLoS One

Gonadotropin-releasing hormone (GnRH)-I and GnRH-II induce cell growth inhibition in human endometrial cancer cells: Involvement of integrin beta3 and focal adhesion kinase

(2009) Dong Park et al.   Reproductive Biology and Endocrinology

Gonadotropin-Releasing Hormones I and II Induce Apoptosis in Human Granulosa Cells

(2008) In-Sun Hong et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Structure/function relationships underlying regulation of FOXO transcription factors

(2008) T Obsil et al.   ONCOGENE