FOXL2, GATA4, and SMAD3 Co-Operatively Modulate Gene Expression, Cell Viability and Apoptosis in Ovarian Granulosa Cell Tumor Cells

Essential but differential role of FOXL2wt and FOXL2C134W in GDF-9 stimulation of follistatin transcription in co-operation with Smad3 in the human granulosa cell line COV434

(2013) David Nonis et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Betaglycan Alters NFκB-TGFβ2 Cross Talk to Reduce Survival of Human Granulosa Tumor Cells

(2013) Maree Bilandzic et al.   MOLECULAR ENDOCRINOLOGY

Molecular Pathogenesis of Granulosa Cell Tumors of the Ovary

(2012) Stacey Jamieson et al.   ENDOCRINE REVIEWS

Discovery of novel protein partners of the transcription factor FOXL2 provides insights into its physiopathological roles

(2012) David L'Hôte et al.   HUMAN MOLECULAR GENETICS

Adult ovarian granulosa cell tumor transcriptomics: prevalence of FOXL2 target genes misregulation gives insights into the pathogenic mechanism of the p.Cys134Trp somatic mutation

(2012) B A Benayoun et al.   ONCOGENE

The Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours

(2012) Roseanne Rosario et al.   PLoS One

GATA4 Deficiency Impairs Ovarian Function in Adult Mice1

(2011) Antti Kyrönlahti et al.   BIOLOGY OF REPRODUCTION

Minireview: Roles of the Forkhead Transcription Factor FOXL2 in Granulosa Cell Biology and Pathology

(2011) Margareta D. Pisarska et al.   ENDOCRINOLOGY

Transcription factor FOXL2 protects granulosa cells from stress and delays cell cycle: role of its regulation by the SIRT1 deacetylase

(2011) Bérénice A. Benayoun et al.   HUMAN MOLECULAR GENETICS

Prognostic significance of FOXL2 mutation and mRNA expression in adult and juvenile granulosa cell tumors of the ovary

(2011) Emanuela D'Angelo et al.   MODERN PATHOLOGY

GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis

(2010) Antti Kyrönlahti et al.   ENDOCRINE-RELATED CANCER

Activin A Regulates Porcine Follicle-Stimulating Hormone β-Subunit Transcription via Cooperative Actions of SMADs and FOXL2

(2010) Pankaj Lamba et al.   ENDOCRINOLOGY

Vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 are highly expressed in ovarian granulosa cell tumors

(2010) Anniina Färkkilä et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary

(2010) Stacey Jamieson et al.   MODERN PATHOLOGY

Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W)

(2010) J-H Kim et al.   ONCOGENE

Aromatase Is a Direct Target of FOXL2: C134W in Granulosa Cell Tumors via a Single Highly Conserved Binding Site in the Ovarian Specific Promoter

(2010) Nicholas I. Fleming et al.   PLoS One

Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation

(2009) N. Henriette Uhlenhaut et al.   CELL

Smad1-Smad5Ovarian Conditional Knockout Mice Develop a Disease Profile Similar to the Juvenile Form of Human Granulosa Cell Tumors

(2009) Brooke S. Middlebrook et al.   ENDOCRINOLOGY

The forkhead transcription factor FOXL2 is expressed in somatic cells of the human ovary prior to follicle formation

(2009) K. Duffin et al.   MOLECULAR HUMAN REPRODUCTION

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

(2009) Sohrab P. Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

GATA-4 Regulates Bcl-2 Expression in Ovarian Granulosa Cell Tumors

(2008) Antti Kyrönlahti et al.   ENDOCRINOLOGY

Aberrant Expression of Ovary Determining Gene FOXL2 in the Testis and Juvenile Granulosa Cell Tumor in Children

(2008) Nicolas Kalfa et al.   JOURNAL OF UROLOGY

GATA4 Is a Direct Transcriptional Activator of Cyclin D2 and Cdk4 and Is Required for Cardiomyocyte Proliferation in Anterior Heart Field-Derived Myocardium

(2008) A. Rojas et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of the GATA Family of Transcription Factors in Endocrine Development, Function, and Disease

(2008) Robert S. Viger et al.   MOLECULAR ENDOCRINOLOGY

Activin signals via SMAD2/3 between germ and somatic cells in the human fetal ovary and regulates kit ligand expression

(2007) Shiona M. Coutts et al.   DEVELOPMENTAL BIOLOGY